Instruction for use: Sodium oxybutyrate solution for injections 20%

Dosage form: solution for intravenous administration of 20%

Active substance: Sodium oxybutirate

ATX

N01AX Anesthetics common others

Pharmacological groups:

Anesthetic means

Antihypoxants and antioxidants

Composition and release form

1 ampoule with 10 ml solution for injection contains sodium oxybutyrate 2 g; in the package 10 pcs.

Pharmachologic effect

Pharmacological action - anesthesia, miorelaksiruyuschee, anti-shock, nootropic, central, antihypoxic, hypnotic, sedative.

It activates metabolic processes in the tissues of the brain, heart, and retina. Stimulates GABAergic transmission of excitation in the central nervous system.

Pharmacodynamics

Increases the contractility of the myocardium, improves microcirculation, increases glomerular filtration (stabilizes kidney function in conditions of blood loss). Increases the resistance of the body, incl. brain, myocardium, retina to oxygen deficiency.

Pharmacokinetics

With iv administration, up to 70% of the drug is excreted from the blood for 2-3 hours.

Indications Sodium oxybutyrate injection 20%

Non-anional anesthesia (introductory and basic, with low-traumatizing operations, with operative delivery, for "rest" for parturient women, for increasing the resistance of the mother and fetus to hypoxia, in elderly patients with hypotension and hypovolemia, in shock), open-angle glaucoma, neuroses, neurosis-like conditions , intoxication and traumatic injuries of the central nervous system, insomnia, narcolepsy.

Contraindications

Hypokalemia, myasthenia gravis.

Application in pregnancy and lactation

Contraindicated in late toxicosis of pregnancy with arterial hypertension.

Side effects

Motor and speech excitement (upon withdrawal from anesthesia); nausea, vomiting; with rapid on IV the introduction - convulsions.

Interaction

Strengthens the effect of analgesic and anesthetic drugs.

Dosing and Administration

IV, slowly (1-2 ml / min), 0.05-0.12 g / kg. The contents of the bottle are previously diluted in 50-100 ml of a 5-40% solution of glucose.

Precautionary measures

With a rapid on IV the introduction of a violation of the rhythm of breathing.

Storage conditions for Sodium oxybutyrate solution for injections 20%

In the dark place.

Keep out of the reach of children.

Shelf life of Sodium oxybutyrate solution for injections 20%

4 years.

Do not use after the expiry date printed on the package.