Instruction for use: Sibazon solution for injections 0,5%

Trade name of the drug – Sibazon solution for injections 0,5%

Active substance: Diazepamum (genus. Diazepami)

Chemical name: 7-Chloro-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one

Dosage Form: solution for injection

Composition of Sibazon solution for injections 0,5%

One ampoule 2 ml solution for injection contains 10 mg of diazepam; pack of 10.

Pharmacotherapeutic group: Anxiolytics

ATX Code

N05BA01 Diazepam

The nosological classification (ICD-10)

F20 Schizophrenia: Dementia praecox; Bleuler's disease; Sluggish schizophrenia; Sluggish schizophrenia apatoabulicheskimi with disabilities; Exacerbation of schizophrenia; The acute stage of schizophrenia with excitement; The acute form of schizophrenia; Acute schizophrenia; Acute schizophrenic disorders; An acute attack of schizophrenia; Psychosis discordant; Schizophreniform psychosis; Dementia early; Febrile form of schizophrenia; Chronic schizophrenia; Chronic schizophrenic disorders; Cerebral organic deficiency in schizophrenia; Schizophrenic state; Schizophrenic psychosis; Schizophrenia.

F48 Other neurotic disorders: Neurosis; Neurological diseases; Neurotic disorders; Neurotic state; Psychoneurosis; Anxious-neurotic state; Chronic neurotic disorders; Emotional reactive disorder.

F48.0 Neurasthenia: Asthenic form of neurasthenia; Asthenoneurotic state; asthenoneurotic disorder; Influenza young workaholics; Flu of yuppie; neurotic disorders; neurasthenic state; neurasthenic syndrome.

F60 Specific personality disorders: The antisocial personality; Psychopathic personality; Psychopathy; Psychopathy excitable type; Psychopathy and psychopathic state; Psychopathy hysterical type; Psychopathy with a predominance of anxiety and worry; Inhibited personality; mood variability; Psychic lability; Emotional shut off; Emotional detachment; Mood changes; mood lability; Instability emotional background; Mixed emotional disorders; Status of emotional stress; Emotional lability; Emotional tension; Emotional instability; Emotional instability; Mood disorders; Mood disorders; mood disorders; Depressed mood; The deterioration of sentiment; mood swings;Hysterical neurosis; Hysterical seizures; Hysterical; Hysteria; Mass (epidemic) hysteria; Fainting hysterical; Hysterical personality.

Pharmacological Properties of Sibazon solution for injections 0,5%Pharmachologic effect

Mode of action - tranquilizing.
Excited benzodiazepine receptors activates potentiates GABAergic system and inhibitory effects of GABA.

Pharmacodynamics

Soothing and anti-anxiety effects are due to the influence of benzodiazepine receptors of the limbic system; muscle relaxant and anticonvulsant - inhibition of spinal reflexes.

Indications for Sibazon solution for injections 0,5%

Neuroses - and psychopathic disorders with stress, anxiety, fear; psychosis, agitation, convulsions, epilepsy, alcohol withdrawal.

Contraindications for Sibazon solution for injections 0,5%

Severe renal failure, myasthenia gravis. Not recommended in the I trimester of pregnancy. Lactating women should abandon breastfeeding.

Sibazon solution for injections 0,5% Dosage and Administration

In / in, in / m. The average single dose - 10 mg (2 ml of 0.5% solution), the average daily - 30 mg. The maximum single dose - 30 mg daily - 70 mg.

Side effect of Sibazon solution for injections 0,5%

Drowsiness, fatigue, headaches, allergic reactions.

Interaction

Enhances deprimic effects of neuroleptics, antidepressants, sedatives, hypnotics, analgesics and anesthetics.

Overdose of Sibazon solution for injections 0,5%

Symptoms: drowsiness, sedation reflexes possible - coma.
Treatment: symptomatic. The specific antidote - flumazenil.

SPECIAL INSTRUCTIONS for Sibazon solution for injections 0,5%

Patients should abstain from alcohol. It is necessary to consider the possible slowing of the rate of reaction.

Storage conditions of Sibazon solution for injections 0,5%

In the dark place at a temperature no higher than 5 ° C.

Keep out of the reach of children.

Shelf life of Sibazon solution for injections 0,5%

3 years.
Do not use beyond the expiration date printed on the package.

Conditions of supply of Sibazon solution for injections 0,5% from pharmacies
On prescription.