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Instruction for use: Protamin-insulinum SMC

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Active substance Insulin-isophan [pork monocomponent]

ATX Code A10AC03 Pork insulin

Pharmacological group


Nosological classification (ICD-10)Z31.1 Artificial insemination

E10 Insulin-dependent diabetes mellitus

Decompensation of carbohydrate metabolism, Diabetes mellitus, Diabetes insulin sugar, Diabetes mellitus type 1, Diabetic ketoacidosis, Insulin-dependent diabetes, Insulin-dependent diabetes mellitus, Coma hyperosmolar non-ketoacidotic, Labile form of diabetes mellitus, Violation of carbohydrate metabolism, Type 1 diabetes mellitus, Type I diabetes mellitus, Insulin-dependent diabetes mellitus, Type 1 diabetes mellitus

Composition and form of release

1 ml of suspension for injection contains insulin of pork highly purified 40 U; In bottles of 10 ml.

pharmachologic effect

Pharmacological action - hypoglycemic.

Regulates carbohydrate metabolism: lowers the level of glucose in the blood, increases its absorption by tissues.

Clinical Pharmacology

The action begins in 2-4 hours, reaches a maximum after 6-12 hours and lasts 18 hours.


Insulin-dependent diabetes mellitus.


Hypersensitivity, hyperglycemic coma.

Side effects

Allergic reactions, hypoglycemia, lipodystrophy at the injection site.

Dosing and Administration

PC; Doses and number of injections are set individually depending on the general condition of the patient, the severity and characteristics of the course of the disease, as well as the level of daily glucosuria and glycemic profile.


Symptoms: hypoglycemia (hunger, weakness, sweating, tremor, headache, palpitation), in severe cases - hypoglycemic coma (loss of consciousness, convulsions, oppression of cardiac activity).

Treatment: reception of sweet tea or sugar; With hypoglycemic coma - 20-40 ml (up to 100 ml) 40% glucose solution IV (intravenously) struino, glucagon n / k (subcutaneously).

Precautionary measures

Not intended for intravenous (intravenous) administration. With caution appoint patients with coronary insufficiency and impaired cerebral circulation.

special instructions

Before use, the bottle must be heated to room temperature, shaken; Rubber bottle cap wipe with alcohol or iodine.

Storage Conditions

In the dark place at a temperature of 1-10 į C.

Keep out of the reach of children.

Shelf life

2 years.

Do not use after the expiry date printed on the package.

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