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DR. DOPING

Instructions

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Instruction for use: Pregnyl

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Active substance: Chorionic gonadotropin

ATX code G03GA01 Chorionic gonadotropin

Pharmacological group

Hormones of the hypothalamus, pituitary gland, gonadotropins and their antagonists

Nosological classification (ICD-10)

E23.0 Hypopituitarism

Kalmann's syndrome, Infantilism pituitary, Dwarfism is cerebral-pituitary, Cachexia pituitary, Cachexia diencephalo-pituitary, Anovulatory disorders, Symmonds disease, Secondary hypogonadism in men, Secondary hypogonadotropic hypogonadism, Hypogenitalism, Hypogonadism, Hypogonadism hypogonadotropic, Hypogonadism of the pituitary, Hypogonadism in men, Hypogonadotropic hypogonadism, Hypopituitarism, Pituitary insufficiency, Lack of growth in children with hypopituitarism, Pangypopituitarism, Primary hypogonadism, Primary hypogonadotropic hypogonadism, Shihan Syndrome, Shihina's Syndrome, Symmonds-Glinsky disease, Laron's dwarfism, Sheena's Syndrome, Syndrome of a fertile eunuch

E23.6.0 * Adiposogenital Syndrome

Adiposogenital Syndrome

E25 Adrenogenital disorders

Macroghenytozomy in boys, Adrenogenital syndrome, Decreased function of the sex glands, Congenital dysfunction of the adrenal cortex, Apera-Halle Syndrome, Crook-Apera-Halle Syndrome

E28 Ovarian dysfunction

Dysfunction of the sex glands, Abnormal ovarian function, Non-functioning ovaries, Primary dysfunction of the ovaries, Decreased function of the sex glands, Estrogen insufficiency

E29 Testicular dysfunction

Hypofunction of gonads in men, Androgenic dysfunction, Dysfunction of the sex glands, Dysfunction of gonads in men, Underdevelopment of the genitals in men, Primary hypogonadism in men

E30.0 Delay in puberty

Later sexual development, Sexual maturation later

N46 Male infertility

Azoospermia, Asthenospermia, Infertility, Infertility male, Marriage is infertile, Dispersion, Violations of spermatogenesis, Oligoastenozoospermia III-IV stage, Oligoastenospermia, Oligozoospermia, Oligospermia, Disorders of testicular functions, Spermatogenesis disorders, Inhibition of spermatogenesis, Yang syndrome

N94.6 Dysmenorrhea Unspecified

Pain during menstruation, Functional disorders of the menstrual cycle, Menstrual cramps, Emmeniopathy, Pain during menstruation, Painful menstrual irregularities, algomenorrhea, algomenoreya, Pain smooth muscle spasm, Pain spasm of smooth muscles (renal and biliary colic, intestinal spasms, dysmenorrhea), Pain spasm of smooth muscles of internal organs (kidney and biliary colic, intestinal spasms, dysmenorrhea), Disalgomenoreya, dysmenorrhea, Dysmenorrhea (essential) (Exfoliative), menstrual disorder, menstruation painful, metrorrhagia, Violation of the menstrual cycle, Menstrual irregularities, Prolaktinzavisimoe menstrual disorders, Prolaktinzavisimoe menstrual dysfunction, Pain spasm of smooth muscles of internal organs, Spasmodic dysmenorrhea, Primary disalgomenoreya

N97 Female infertility

Female infertility in anovulation, Hyperprolactinemic infertility, Hyperprolactinaemia with infertility, Endocrine infertility, Infertility due to hypothalamic-pituitary dysfunction, Infertility infertility, Infertility, Infertility on the background of hyperprolactinaemia, Functional infertility, Marriage is infertile, Infertility of ovarian genesis, Stimulation of the growth of a single follicle

Composition and form of release

1 ampoule with lyophilized powder for the preparation of the injection solution contains human chorionic gonadotropin 500, 1500 or 5000 IU; In a planar cell pack complete with a solvent in ampoules of 1 ml, in a box of 3 sets.

pharmachologic effect

Pharmacological action - gonadotropic.

Stimulates the production of testosterone (in men), estrogens and progesterone after ovulation (in women). Enhances steroidogenesis in the sex glands.

Indications

In men, hypogonadotropic hypogonadism, impaired spermatogenesis, delay in puberty in case of insufficient gonadotropic function of the pituitary gland, cryptorchidism; In women - induction of ovulation and superovulation, incl. Before puncturing the follicles, maintaining the function of the yellow body.

Contraindications

Androgen-dependent tumors (including suspected).

Side effects

Rarely - skin rash; In men, sodium and water retention (when taking high doses). After treatment, there is an increased risk of miscarriage or the development of multiple pregnancies.

Dosing and Administration

Injectively. With hypogonadotropic hypogonadism, dyspermia, delay in rates of puberty in men - 1000-2000 IU 2-3 times a week; When cryptorchidism, children under the age of 6 years - 500-1000 IU 2-3 times a week, over 6 years - 1500 ME 2-3 times a week; Course - 6 weeks, if necessary, can be repeated. To induce ovulation after treatment with humegonom - 5000-10000 IU, once, to maintain the function of the yellow body - 5000-10000 IU 1-3 times (within 9 days after ovulation / puncture of the follicles).

Precautionary measures

They are cautiously prescribed to boys in the prepubertal period, as well as to patients with heart failure, renal dysfunction, arterial hypertension, epilepsy, migraine (including if they have an anamnesis). The drug is recommended to be canceled in case of development of the syndrome of ovarian hyperstimulation.

Storage Conditions

In the dark place at a temperature of 2-15 ° C.

Keep out of the reach of children.

Shelf life

3 years. 5 years solvent

Do not use after the expiry date printed on the package.

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