Instruction for use: Posterisan forte

Dosage form: Ointment for rectal and external use; Rectal suppositories

ATX

C05AX Hemorrhoids and anal cracks for topical use others

Pharmacological group

Other immunomodulators

The nosological classification (ICD-10)

I84 Hemorrhoids: Painful hemorrhoidal nodes; External hemorrhoids; Internal hemorrhoids; Inflammation of hemorrhoids; Exacerbation of hemorrhoids; Chronic bleeding hemorrhoids; Acute hemorrhoidal attack

K60 Crack and fistula of anus and rectum area: Anal fissure; Acute anal fissure; Paraproctitis chronic; Perianal fissure; Surface fissure of anus; Fistulas of the rectum; Rectum crack; Anal cracks; Cracks in the anus; Rectal cracks; Chronic anal fissures; Chronic periproctitis; Watchdog

K62.8.0 * Anterior papillitis: Anopapillitis

L29.0 Anus of the anus: Anal eczema; Anal itching; Anogenital itching; Dermatitis and eczema in the anal area; Perianal dermatitis; Itching anal; Anogenital itching; Itching of the anorectal region; Itching in the genital and anus; Itching in the anus; Eczema anal region; Perianal dermatitis

L29.3 Anogenital itching, unspecified: Itching in the genital and anus; Anal itching; Anogenital itching; Genital itching; Anogenital itching; Itching of the anorectal region; Itching of the vulva; Itching of the genitals; Perianal dermatitis

Composition and release form

Ointment 1 g

Microbial cells of Escherichia coli killed by phenol 500 million

Hydrocortisone (in 166.7 mg of an aqueous suspension) 2.5 mg

Auxiliary substances: lanolin; Vaseline (yellow) or paraffin (yellow, soft); phenol

In tubes of aluminum (with applicator) for 25 grams, complete with an applicator; In the box 1 tuba.

Suppositories rectal 1 supp.

Microbial cells of Escherichia coli killed by phenol 1000 million

Hydrocortisone (in 387.1 mg of an aqueous suspension) 5 mg

Excipients: solid fat; Macrogolglycerol; Hydroxystearate; Acetylcysteine; Phenol (preservative); Ethylenediaminetetraacetate disodium salt

In the blistere 5 pcs .; In the box 2 blisters.

Pharmachologic effect

Mode of action - anti-inflammatory, immunostimulating, antiallergic, antipruritic, regenerative.

It forms a specific and stimulates nonspecific immunity.

Pharmacodynamics

Combined drug, which consists of two active components - a suspension of bacterial culture containing inactivated bacteria and their metabolic products, and hydrocortisone. It stimulates the T-system of immunity, increases the phagocytic activity of leukocytes and cells of the reticuloendothelial system, increases the role of a number of humoral factors of nonspecific immunity (induces the formation of cytokines), enhances the formation of antibodies at the site of exposure. Concentrated lipopolysaccharides of cell membranes and metabolites of Escherichia coli of various strains, incl. Resistant to the action of antibiotics and other antibacterial agents, lead to an increase in local tissue resistance to the effects of pathogenic microflora. Hydrocortisone (contained in a small dose) supplements the effect of a suspension of bacterial culture due to anti-inflammatory, antiallergic and antipruritic action, which is manifested in a decrease in exudation, normalization of the permeability and tone of blood vessels, reduction of edema, hyperemia, itching, stimulation of regeneration of damaged tissues.

Indication of the drug Posterisan forte

Hemorrhoids (mainly suppositories); Dermatitis and eczema in the anus (ointment); Anal and genital itching; Allergic skin lesions (ointment); Anopapillitis, cracks in the anal region, incl. Painful (ointment), conditions after operations on the anorectal area (to stimulate wound healing). It is recommended mainly in acute cases.

Contraindications

Hypersensitivity to phenol, specific lesions of the anogenital area (including tuberculosis, syphilis, gonorrhea, mycoses, viral diseases).

Application of pregnancy and breastfeeding

Use with caution in the first trimester of pregnancy.

Side effects

Rarely - allergic reactions (associated with the use of phenol as a preservative). With prolonged use in high doses, it is impossible to exclude the development of systemic effects characteristic of GCS.

Dosing and Administration

Externally, rectally. Apply a thin layer on the affected area in the morning and evening, as well as after each bowel movement. For a deeper introduction of the ointment into the anal canal, a screw applicator can be used. Suppositories rectal in the acute period of the disease are used for 2-3 pcs. per day. After eliminating the subjective symptoms of the disease, the affected area continues to be lubricated once a day or injected 1 supp. 1 time per day for several days. If the drug is used to treat chronic dermatitis, then after the disappearance of skin manifestations it is recommended to prolong therapy for another 1-2 weeks. It is possible to combine the use of ointments and suppositories. After the completion of the course of treatment to fix the therapeutic effect, it is advisable to use the preparation (ointments or suppositories) that does not contain hydrocortisone for another 2-3 weeks.

Manufacturer

Dr. Kade, Germany

Storage conditions of the drug Posterisan forte

In dry, the dark place at a temperature of 0-25 ° C.

Keep out of the reach of children.

Shelf life of the drug Posterisan forte

Ointment for rectal and external use - 3 years.

Suppositories rectal - 2 years.

Do not use after the expiry date printed on the package.