Instruction for use: Polyoxidinum

Dosage form: Solution for infusions

Active substance: Kalii iodidum +Natrii chloridum+ Polyaethylenglycolum

ATX

B05AA Blood substitutes and blood plasma preparations

Pharmacological group

Substitutes for plasma and other blood components in combinations

Composition and release form

Solution for infusion - 1 liter

Polyethylene glycol 15 g

Sodium chloride 9 g

Potassium iodide 0.5 g

Water for injection 1000 ml

In bottles for blood substitutes of 200 and 400 ml.

Pharmachologic effect

Mode of action - Antiplatelet, antishock, plasma-substituting, normalizing rheological properties of blood.

Dosing and Administration

IV by stream infusion or by drop infusion. Adults in a dose of 400-800 ml per administration, children - 15-20 ml / kg of body weight; If necessary, the amount can be increased: adults up to 1200 ml, children up to 30 ml / kg body weight. The rate of administration is determined by the patient's condition, blood pressure and venous pressure, heart rate, hematocrit. With the normalization of hemodynamic parameters, it is advisable to switch to the drop method of administration. With blood loss more than 500-700 ml and severe anemia, the infusion of the drug is combined with blood transfusion. As the central venous pressure increases, the dose and rate of administration of the drug are reduced.

For prophylaxis of an operational shock, the drug is administered intravenously, drip by an adult at a speed of 60-80 drops per min, children - 30-40 drops per minute with a transition to a jet in the event of a fall in blood pressure.

In operations using the apparatus of artificial circulation, the drug is used as a hemodilution to fill the device (40-60% perfusion solution).

Manufacturer

OJSC "Biosintez", Russia.

Storage conditions of the drug Polyoxidinum

In a dry place at a temperature of 10-30 ° C. At a temperature of 40-45 ° C - no more than 2 months.

Keep out of the reach of children.

The shelf life of the drug Polyoxidinum

2 years.

Do not use beyond the expiration date printed on the package.