Instruction for use: Pentoxyl

Trade name of the drug – Pentoxylum

The Latin name of the substance Pentoxyl

Pentoxylum (genus. Pentoxyli)

Chemical name

4-Methyl-5-hydroxymethyluracil

Gross formula

C6H8N2O3

Pharmacological groups:

Regenerants and reparants

Stimulators of hematopoiesis

The nosological classification (ICD-10)

D72 Other disorders of white blood cells: Lymphocytopenia; Hereditary neutropenia

D84.9 Unspecified Immunodeficiency: Pneumonia in immunodeficient states; Autoimmune disease; Autoimmune diseases; Severe immunodeficiency; immune deficiency; Immunodeficiency; immunodeficiency diseases; Immunodeficiency states due to surgery; Immunotherapy for cancer; Immunomodulation; Infections in patients with weakened immune systems; Correction of immune deficiency; Correction of immunodeficiencies; Correction of a weakened immune system; Correction of a weakened immunity in immunodeficient states; Violation of immunity; Violation of the immune status; Immune System Disorders; Primary immunodeficiency; Maintaining immunity; Lowering the body's defenses; Lowering the immunity; Lowering the immunity of colds and infectious diseases; The decrease of the immune status; Lowered resistance to infections; Lowered resistance to infections and colds; Lowered resistance; Immunosuppression; Predisposition to colds; acquired immune deficiencies; Radiation immunodeficiency; The development of immunodeficiency; Immune dysfunction syndrome; immunodeficiency syndrome; primary immunodeficiency syndrome; Reducing the body's defenses; Immunosuppression; Reduced immune defense; Reducing local immunity; Reducing the total body resistance; The decrease in cell-mediated immunity; Reduced resistance to infections in children; Reducing the body's resistance; Reduced resistance; reduced immunity; Status immunodeficiency; Stimulation of the processes of nonspecific immunity; Heavy selective secondary immunodeficiency; immunity Oppression; Primary immunodeficiency

J03.9 Acute tonsillitis, unspecified (angina agranulocytic): Throat infections; Acute tonsillitis; Angina; Follicular tonsillitis; Angina alimentary-hemorrhagic; Secondary sore throat; Sore throat primary; Angina follicular; Inflammatory diseases of the tonsils; Catarrhal angina; Lacunar angina; Acute Sore Throat; Tonsillitis; Tonsillitis acute; Tonsillar angina; Follicular sore throat; Bacterial tonsillitis

J98 Other respiratory disorders

K05.4 Periodontal disease: Alveolar pyorrhea; Amphodontosis; Chronic parodontosis; Superficial and deep periodontitis; Pyorrhea

T52.1 Toxic effect of benzene: Benzene intoxication; Intoxication with benzene; Chronic intoxication with benzene; Chronic benzene poisoning

CAS Code

147-61-5

Characteristics of the substance Pentoxyl

The pyrimidine derivative. White crystalline powder with a faint smell of formaldehyde. Very little soluble in water, soluble in solutions of caustic alkalis, practically insoluble in ethanol.

Pharmacology

Mode action - Immunostimulating, leukopoietic.

Stimulates the synthesis of nucleic acids, leukopoiesis, antibody formation, phagocytosis. Accelerates the processes of cellular regeneration, promotes the healing of wounds, has an anti-inflammatory effect.

There are data on the effectiveness of use in patients with trophic ulcers, burns, bone fractures, peptic ulcer of the stomach and duodenum. Effective in the treatment of chronic pancreatitis, incl. In children, due to stimulation of reparative processes in the pancreas (Rimarchuk GV, 1999). Along with other immunomodulators used in the treatment of herpesvirus infection, but not earlier than the 21st day with acute and 14th day with a recurrent process (Khakhalin LN, 2000). It is possible to use in order to increase the general resistance of the organism when carrying out complex antigen-specific immunoprophylaxis (immunocorrection).

Application of the substance Pentoxyl

Leukopenia, agranulocyte angina, alimentary-toxic aleukia, intoxication with benzene, infectious and inflammatory diseases of the respiratory system (often recurrent), immunodeficiency states, periodontitis (as part of combination therapy).

Contraindications

Hypersensitivity, hemoblastosis, leukemia, lymphogranulomatosis, malignant neoplasms of the bone marrow.

Side effects of the substance Pentoxyl

Headache, dizziness, dyspeptic phenomena, allergic reactions.

Routes of administration

Inside.