Instruction for use: Limontar

Trade name of the drug – Limontar

International nonproprietary name Citric acid + Succinic acid

Limontar reduces the toxic effect of alcohol. It stimulates the production of energy in the cell, activates the functions of organs and tissues, thereby it’s able to improve pregnancy course, fetal growth and development.

Pharmacotherapeutic group: Metabolic drug

ATC code: À15

Pharmacological properties:

Limontar acts as a tissue metabolic regulator, enhances the oxidation-reduction processes and the production of ATP; as a result, it has antioxidant and anti-hypoxic properties and is able to:

activate functions of organs and tissues;

increase reactivity of the organism;

enhance mental and physical efficiency;

enhance pregnancy course, fetal growth and development;

increase secretion of the gastric acid, production of hydrochloric acid, enhance an appetite;

decrease the toxic effect of alcohol.

Effect of Limontar occurs in 10-20 min after the intake.

Pharmacokinetics

Citric and succinic acid are completely metabolized into water and carbon dioxide; their accumulation in the organism doesn’t occur.

Indications

Limontar is used: as a drug for increasing of non-specific reactivity of the pregnant women organism, enhancing their adaptation and compensation abilities for prevention of hypoxia complications, fetus hypotrophy, and pregnancy loss. It is used for prevention of alcohol intoxication; in treatment of acute alcohol intoxication of mild or medium severity for decreasing of the toxic effect of alcohol and post-toxic disorders; in complex therapy of dipsomania in patients with alcohol addiction; for complex treatment of asthenovegetative disorder (common weakness, decreasing of efficiency, loss of appetite) at a periods of alcohol abstinence syndrome. Limontar is also used as a test-breakfast in analysis of secretory and acid-forming gastric functions (diagnostic utility of Limontar and that of histamine are equal).

Contraindications

Hypersensitivity, arterial hypertension, ischemic heart disease (including angina pectoris), glaucoma, gastroduodenal ulcer in acute stage, late gestosis (severe grade).

Limontar Dosage and administration:

Limontar is administered orally before meals. The tablet should be grinded up and dissolved in water with a small pinch of baking soda before intake. The mineral water can be used for dissolving.

For pregnant women: 1 tablet once a day for 10 days in the first trimester (at 12-14 weeks of gestation) and in the second trimester (at 24-26 weeks of gestation). In the third trimester Limontar is prescribed 10-25 days before delivery. The total dose of Limontar during pregnancy is 5.0-7.5 g.

For prevention of alcohol intoxication: 1 tablet in 20-60 minutes before alcohol ingestion.

During acute alcohol intoxication: 1 tablet 2-4 times a day every 1-2.5 hours.

For relief of dipsomania: 1 tablet 3-4 times a day for 4-10 days, either alone or in combination with conventional treatment.

For the “test-breakfast” in analysis of secretory and acid-forming gastric functions: 1 tablet, previously dissolved in 10-15 ml of water, orally on an empty stomach.

In case of feeling of heaviness in the epigastrium: Limontar is administered after meal.

Adverse reactions

Pain in the epigastrium (usually this phenomenon subside in 3-5 min without any treatment), increased secretion of gastric juice may occur. In persons who are prone to high blood pressure, blood pressure may increase after intake of the drug.

Dosage form

50 mg + 200 mg soluble tablets.

Blister with 30 tablets in cardboard pack together with the patient information leaflet.

Storage conditions

Store in a dry place at a temperature under 25 °C, protect from light.

Keep out of the reach of children.

Shelf life

3 years. Do not use after labeled expiration date.

Prescription status

No prescription required.