Instruction for use: KornamI want this, give me price
Trade name of the drug – Kornam
Active substance: Terazosinum
Dosage Form: tablets
Composition (per tablet): 1 tablet contains terazosin monohydrochloride dihydrate in the form of 2 or 5 mg; in blister 10 pcs., in box 2 of the blister.
Drugs affecting the metabolism of the prostate gland and correctors urodynamics
ATX G04CA03 Terazosin
The nosological classification (ICD-10)
I10 Essential (primary) hypertension: hypertension; Arterial hypertension; Arterial hypertension crisis course; Essential Hypertension; Essential hypertension; Essential hypertension; Essential hypertension; Essential hypertension; Primary hypertension; Arterial hypertension, complications of diabetes; The sudden increase in blood pressure; Hypertensive disorders of blood circulation; hypertensive condition; hypertensive crises; arterial Hypertension; malignant Hypertension; Hypertonic disease; hypertensive crises; accelerated hypertension; malignant hypertension; The aggravation of hypertensive disease; Transient hypertension; Isolated systolic hypertension
I15 Secondary hypertension: Arterial hypertension, complications of diabetes; hypertension; The sudden increase in blood pressure; Hypertensive disorders of blood circulation; hypertensive condition; hypertensive crises; hypertension; arterial Hypertension; malignant Hypertension; hypertensive crises; accelerated hypertension; malignant hypertension; The aggravation of hypertensive disease; Transient hypertension; hypertension; Arterial hypertension; Arterial hypertension crisis course; renovascular hypertension; Hypertension symptomatic; Renal hypertension; Renovascular hypertension; renovascular hypertension; Symptomatic hypertension
N40 Hyperplasia of prostate gland: Prostate adenoma; BPH; Prostatauxe; prostate Hypertrophy; Dysuric disorders caused by benign prostatic hyperplasia; Dizuricheskie disorder with benign prostatic hyperplasia; Dysuria with prostate cancer; Benign prostatic giperpalaziya; Benign prostatic hyperplasia; Benign prostatic hyperplasia stages 1 and 2; Benign prostatic hyperplasia I degree; Benign prostatic hyperplasia II degree; Benign prostatic hypertrophy; The disease of the prostate gland; Acute urinary retention related to benign prostatic hyperplasia; Benign prostatic hyperplasia stages 1 and 2 in combination with prostatitis; paradoxical ischuria
Pharmacological Properties of Kornam
Pharmachologic effect - Mode of action - alpha adrenoliticheskoe.
Selectively blocking the alpha 1-adrenergic receptors of smooth muscle of the arterioles and veins, prostatic capsule, bladder neck and upper urethra. It inhibits vasoconstriction, reduces peripheral vascular resistance and venous return, reduces blood pressure. There is no tolerance or reflex tachycardia.
It normalizes urination and improves the symptoms of benign prostatic hyperplasia. No effect on bladder contraction. Urination is improved by 2-4 weeks of therapy. In patients with hypertension treatment of benign prostatic hyperplasia with normal blood pressure does not cause a clinically significant reduction in blood pressure.
It promotes normalization of plasma lipid profile, lowers cholesterol, LDL and very low density. Perhaps the appointment of patients with peripheral arterial angiopathy. It has no side effects on metabolic processes, and can be used in patients with diabetes, asthma, gout.
terazosin treatment reduces left ventricular hypertrophy.
Quickly and completely absorbed from the gastrointestinal tract by ingestion (food intake does not affect the metabolism). Cmax achieved within 1 h is metabolized in the liver.; most of the excreted in the bile. T1 / 2 -. 12 hours Pharmacokinetics in patients with renal insufficiency, the elderly and patients with moderate hypertension does not differ from the pharmacokinetics of the drug in patients with normal blood pressure.
Indications for Kornam
Symptomatic treatment of benign prostatic hyperplasia; monotherapy hypertension mild to moderate treatment in combination with other antihypertensive agents severe hypertension.
Contraindications for Kornam
Hypersensitivity, pregnancy, breastfeeding, child.
Kornam Dosage and Administration
Inside, 1 time a day at bedtime.
In benign prostatic hyperplasia initial dose is 1 mg / day, with a gradual increase to 2, 5 and 10 mg / day to achieve the optimal effect.
When hypertension - an initial dose of 1 mg, then gradually increased, achieving stabilization of blood pressure.
The maximum daily dose of 20 mg.
Pregnancy and breast-feeding
Contraindicated. At the time of treatment should stop breastfeeding.
Side effect of Kornam
Rarely - headache, dizziness, fatigue, sleep disturbance (insomnia or drowsiness), retrograde ejaculation, decreased libido, pain, back pain, rhinitis, nausea, vomiting, constipation or diarrhea. In extremely rare cases - hypersensitivity reactions (rash, pruritus, angioedema). In rare cases - orthostatic hypotension, tachycardia, palpitations, chest pain.
Overdose of Kornam
Treatment: Take the prone position and then head down - symptomatic. Dialysis is ineffective.
The effect of increasing other antihypertensive drugs. In clinical studies, while the use of NSAIDs, antibiotics, anticholinergics / sympathomimetic agents, uricosuric agents, antihistamines, oral lipid-lowering, corticosteroids, antacids, sedative, tranquilizing, diuretic drugs and beta-adrenergic blockers clinically significant effects were detected.
SPECIAL INSTRUCTIONS for Kornam
In order to reduce the risk of hypotension and syncope ortostaticheckoy treatment should start with the lowest dose (gradually increasing in the future) in the supine position and under the supervision of a physician. Not recommended activities requiring attention concentration (driving vehicles, etc.) for 12 hours after the first dose, or increasing after treatment interruption. In controlled clinical trials for the treatment showed a decrease in hematocrit, hemoglobin, white blood cells, blood albumin and total protein.
Storage conditions of Kornam
At a temperature no higher than 25 ° C.
Keep out of the reach of children.
Do not use beyond the expiration date printed on the package.