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Instructions

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Instruction for use: Jodostin

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ATX Code H03CA Potassium Jodid

Active substance Potassium Jodid

Pharmacological group

Inorganic iodine preparation [Thyroid and parathyroid hormones, their analogs and antagonists (including antithyroid agents) / 67 /]

Nosological classification (ICD-10)

E01 Thyroid gland diseases associated with iodine deficiency and similar conditions

Hormonal deficiency of the thyroid gland due to iodine deficiency in the body, Goiter endemic, Iodine deficiency alimentary state, Iodine deficiency disease, Iodine Deficiency, Endemic cretinism

Composition and form of release

1 tablet, coated, contains potassium iodide 0.1308 mg, which corresponds to 0.1 mg of iodine; In a planar cell pack of 20 or 50 pcs., In a cardboard bundle 5 or 2 packs, respectively.

pharmachologic effect

Pharmacological action - filling iodine deficiency.

Prevents the development of endemic goiter, normalizes the production of thyroid hormones.

Pharmacodynamics

In the thyroid gland, it is oxidized to elemental iodine, which is used to iodize tyrosine with conversion to mono and diiodotyrosine, the precursors of thyroid hormones.

Pharmacokinetics

Absorbed in the small intestine and distributed in the intracellular space. It accumulates, in addition to the thyroid gland, in the salivary and mammary glands, the stomach.

Indication of the drug Jodostin

Prophylaxis of goiter (endemic, relapse after strumectomy, etc.) and iodine deficiency during pregnancy; Treatment of diffuse euthyroid goiter and other iodine deficiency conditions in children and adults.

Contraindications

Hypersensitivity to iodine, manifest hyperthyroidism, subclinical hyperthyroidism (for doses exceeding 150 mcg / day), herpetiform dermatitis; Toxic adenoma and nodular goiter (for doses exceeding 300 mcg / day, except for preoperative therapy for the purpose of blocking the thyroid gland), hypothyroidism (except for cases caused by severe iodine deficiency), thyroid cancer, including a suspect.

pregnancy and lactation

possible

Side effects

On the part of the digestive tract: metallic taste in the mouth, vomiting, diarrhea, diarrhea.

Allergic reactions: dermatitis (exfoliative, vesicular, etc.), Quincke's edema, iodine fever, iodine acne, edema of the salivary glands, rhinitis.

Other: hyperthermia, anxiety, headache, hyperthyroidism (when used at doses exceeding 300 μg / day), goiter and hypothyroidism (at doses above 1 mg / day).

Interaction

Weaken the action of thyreostatics. With the simultaneous use in high doses with potassium-sparing diuretics, the risk of hyperkalemia, with lithium-goitre and hypothyroidism increases. Perchlorate and thiocyanate inhibit the absorption of iodine by the thyroid gland.

Dosing and Administration

Inside, after eating, squeezed a lot of liquid, once a day. Prevention of endemic goiter: adults and adolescents - 100-200 mcg / day, newborns and children under 14 years - 50-100 mcg / day, with pregnancy and lactation - 150-200 mcg / day. Prevention of recurrence of goiter after surgical removal: 100-200 μg daily. Treatment of euthyroid goiter: adults - 150-200 mcg / day; Newborns, children and adolescents - 100-200 mcg / day.

Precautionary measures

Before the beginning of treatment it is necessary to exclude malignant lesion of the thyroid gland.

storage Conditions

In dry, the dark place at a temperature of no higher than 25 C.

Keep out of the reach of children.

Shelf life

3 years.

Do not use after the expiry date printed on the package.

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