Instruction for use: Feloran 25
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Active substance Diclofenac
ATX Code M01AB05 Diclofenac
Pharmacological group
NSAIDs - Acetic acid derivatives and related compounds
Nosological classification (ICD-10)
M06.9 Other specified rheumatoid arthritis
Rheumatoid arthritis,Pain syndrome in rheumatic diseases, Pain in rheumatoid arthritis, Inflammation in rheumatoid arthritis, Degenerative forms of rheumatoid arthritis, Children's rheumatoid arthritis, Exacerbation of rheumatoid arthritis, Acute articular rheumatism, Rheumatic arthritis, Rheumatic polyarthritis, Rheumatoid arthritis, Rheumatic polyarthritis, Rheumatoid arthritis, Rheumatoid arthritis of active course, Rheumatoid arthritis, Rheumatoid polyarthritis, Acute rheumatoid arthritis, Acute rheumatism
M08 Juvenile [juvenile] Arthritis
Juvenile arthritis, Juvenile chronic polyarthritis, Juvenile chronic arthritis, Juvenile rheumatoid arthritis, Arthritis juvenile chronic
M10 Gout
Exacerbation of gout, Acute articular attack with gout, Acute gouty attack, Gouty attack, Recurrent gout attacks, Chronic gout
M13.0 Unspecified polyarthritis
Polyarthritis, Inflammatory diseases of joints, Nonspecific polyarthritis, Exchange polyarthritis, Polyarthritis, Polyarthropathy, Subchronic polyarthritis, Chronic polyarthritis, Pain with osteoarthritis, Polyarthritis of unclear etiology
M13.9 Arthritis, unspecified
Arthritis,Purulent arthritis (non-infectious), acute Arthritis,Pain in acute inflammatory diseases of the musculoskeletal system,Pain in chronic inflammatory diseases of the musculoskeletal system,The pain in osteoarthritis, Inflammation in osteoarthritis, Inflammatory arthropathy, Inflammatory and degenerative joint diseases, Inflammatory disease of the musculoskeletal system, Inflammatory joint disease, Inflammatory diseases of the musculoskeletal system, destructive arthritis, The disease of the musculoskeletal system, Diseases of the musculoskeletal system, Diseases of the musculoskeletal system and connective tissue, Infections musculoskeletal system, monoartrit, Non-infectious arthritis, rheumatic arthritis, Osteoarthritis, Acute inflammation of the musculoskeletal tissue, Acute inflammatory diseases of the musculoskeletal system, Acute inflammatory condition of the musculoskeletal system, Acute arthritis, Acute osteoarthritis, Post-traumatic osteoarthritis, Reactive arthritis, Chronic inflammatory diseases of the joints, Chronic arthritis, Chronic inflammatory arthritis, Chronic inflammation of the inner layer of the joint capsule, Chronic inflammation of the joint capsule,Chronic inflammatory disease of the joints, Exudative arthritis
M15-M19 Osteoarthritis
M16 Coxarthrosis [arthrosis of the hip joint]
Hip osteoarthritis
M45 Ankylosing spondylitis
Ankylosing spondylarthrosis, Marie-Strumpel disease, Ankylosing spondylitis, Pain syndrome in acute inflammatory diseases of the musculoskeletal system, Pain syndrome in chronic inflammatory diseases of the musculoskeletal system, Bechterew's disease, Ankylosing spondylitis, Diseases of the spinal column, Rheumatic spondylitis, Bechterew-Marie-Strumpel disease
M47 Spondylosis
Spondyloarthrosis, spondylarthrosis, Diseases of the spinal column, spondylosis
M54.4 Lumbago with sciatica
Pain in the lumbosacral spine, Lumbago, Sciatica, Lumbar syndrome
M60 Myositis
Myositis, Fibrositis Fibromyositis, Inflammatory disease of soft tissues
M71 Other bursopathies
Bursitis, Bursopathy, Diseases of soft tissues, Osteoarthritis in musculo-articular diseases, Inflammatory disease of soft tissues, Subacute bursitis
M77.9 Other unspecified
Capsule, Periarthritis, Tendonitis, Tendopathy, Periarthropathy
M79.0 Other unspecified rheumatism
Degenerative rheumatic disease, Degenerative and rheumatic diseases of the tendons, Degenerative rheumatic diseases, Localized forms of rheumatism of soft tissues, Rheumatism, Rheumatism with a pronounced allergic component, Rheumatism of the articular and extraarticular, Rheumatic attack, Rheumatic complaints, Rheumatic diseases, Rheumatic disease of the spine, Relapses of rheumatism, Articular and extra-articular rheumatism, Articular and muscular rheumatism, Articular rheumatism, Articular syndrome with rheumatism, Chronic rheumatic pain, Chronic articular rheumatism, Rheumatoid diseases, Rheumatic diseases of the intervertebral disc
M79.2 Neurology and neuritis, unspecified
Pain syndrome with neuralgia, Brachialgia, Occipital and intercostal neuralgia, Neuralgia, Neuralgic pain, Neuralgia, Neuralgia of intercostal nerves,Neuralgia of the posterior tibial nerve, Neuritis, Neuritis traumatic, Neuritis, Neurological Pain Syndromes, Neurological contractures with spasms, Acute neuritis, Peripheral neuritis,Post-traumatic neuralgia,Severe pain of a neurogenic nature, Chronic neuritis, Essential neuralgia
N94.0 Pain in the middle of the menstrual cycle
Algomenorea, Painful menstruation, Menalgia, Pain in menstruation
N94.3 Premenstrual tension syndrome
Pronounced premenstrual syndrome, Menstrual psychosomatic disorder, Menstrual syndrome, Premenstrual tension, Premenstrual status, Premenstrual period, Premenstrual syndrome, Menstruation syndrome
R52.2 Other constant pain
Pain syndrome, rheumatic origin, Pain at vertebral lesions, Pain in the chamber, Pain for burns, Pain syndrome weak or moderate, Perioperative pain,Moderate to severe pain, Moderately or weakly expressed pain syndrome, Moderate to severe pain, Ear pain of otitis, Neuropathic pain, neuropathic pain
T08-T14 Injuries to unspecified part of trunk, limb or body region
Composition and form of release
1 tablet, coated with enteric coating, contains diclofenac sodium 25 mg; in a contour acheikova packing 10 pcs., in a box 3 packings.
1 retard tablet, coated with enteric coating, - 100 mg; in a contour acheikova packing 10 pcs., in a box 3 packings.
pharmachologic effect
Pharmacological action - anti-inflammatory, antipyretic, antiaggregational, analgesic.
It blocks cyclooxygenase and inhibits the synthesis of PG (prostaglandins).
Indications
Articular syndrome: rheumatoid arthritis, ankylosing spondylitis, mono- and polyarthritis, incl. juvenile chronic polyarthritis; degenerative joint diseases: arthrosis, coxarthrosis, spondylarthrosis, rheumatic soft tissue damage: periarthritis, bursitis, tenosynovitis, fibrositis, myositis; gout; neuralgia, neuritis, lumboschialgia; post-traumatic syndrome; obstetric-gynecological pain, painful edema and inflammation after surgical interventions.
Contraindications
Hypersensitivity (including to other NSAIDs), blood disorders of unknown origin, peptic ulcer and duodenal ulcer, bronchial asthma, severe disorders of the liver and kidneys, children's age (up to 6 years, for retard tablets - up to 16 years ).
pregnancy and lactation
Contraindicated in the third trimester of pregnancy.
Side effects
On the part of the intestine: nausea, vomiting, diarrhea, ulceration and bleeding in the digestive tract, rarely - lack of appetite, cramps in the abdomen, a feeling of overflow, increased levels of transaminases, hepatitis, jaundice, pancreatitis.
From the side of the central nervous system: dizziness, headache, sleep disturbance, fatigue, irritability, excitability, taste disorder, visual disturbances (double vision), tinnitus, hearing impairment, memory disorders, disorientation, fear, convulsions, tremors and depressions .
On the part of the blood: anemia, leukopenia, agranulocytosis, thrombocytopenia.
From the urinary system: proteinuria, hematuria, interstitial nephritis, nephrotic syndrome.
Allergic reactions: increased photosensitivity, eczema, erythema, pinpoint hemorrhages in the skin, Stevens-Johnson syndrome, Lyell's syndrome, swelling of the face, tongue and throat with narrowing of the respiratory tract, difficulty breathing, asthmatic attack, tachycardia, increased blood pressure, rarely vasculitis, pneumonitis .
Interaction
Reduces the plasma level of digoxin, phenytoin and lithium preparations, weakens the effect of diuretics and hypotensive drugs. Increases the gastro-toxicity of NSAIDs and glucocorticosteroids, potentiates hyperkalemia with the intake of potassium-sparing diuretics, increases the toxic effect on the kidneys of methotrexate and cyclosporine. Acetylsalicylic acid reduces the concentration by 20%.
Dosing and Administration
Inside, not liquid, with a sufficient amount of liquid, during or after a meal. The daily dose is 75-150 mg. For long-term treatment - 75-100 mg per day in 2-3 divided doses. For relief of pain at night and with morning stiffness, combine tablets in the afternoon with 1 table. retard in the evening, before bed. Children older than 5 years - 2-3 mg / kg body weight per day in 2-3 hours.
Tablets retard without chewing and not dividing, according to 1 table. 1 time per day.
Precautionary measures
It is necessary to control the level of sugar in the blood when combined with antidiabetic drugs and the time of blood coagulation against the background of anticoagulants.
storage Conditions
In dry, the dark place at a temperature of 15-21 ° C.
Keep out of the reach of children.
Shelf life
3 years.
Do not use after the expiry date printed on the package.