Instruction for use: Diphenhydramine + Naphazoline (Diphenhydraminum + Naphazolinum)

Pharmacotherapeutic group:

H1-antihistamines in combination

Alpha-adrenoceptor agonists in combination

Ophthalmic agents in combination

Pharmacology

Pharmacological effect

Combined preparation has H1-antihistamine (diphenhydramine) and vasoconstrictor (naphazoline) action. It reduces swelling of the conjunctiva.

Indications

Allergic conjunctivitis.

Contraindications

Hypersensitivity (including to sympathomimetic amines), angle-closure glaucoma, pregnancy, lactation, children's age (up to 2 years).

Precaution

Hyperthyroidism, hypertension, atherosclerosis, arrhythmia, chronic rhinitis, bronchial asthma, adrenal adenoma, advanced age.

Dosage

Enter into the conjunctival sac 1-3 times daily for 1-2 cap.

Side effect

Burning, itching, redness, conjunctival irritation, eye pain, visual disturbances, dry nasal mucosa. Mydriasis, increased intraocular pressure. Described an isolated case of corneal clouding (when used within 7 days of at least 10 times a day), which disappeared after discontinuation of treatment.

Rarely - systemic side effects: drowsiness, palpitations, increased blood pressure, headache, dizziness, nausea.

Overdose

Symptoms: long-term and frequent use in children under 6 years old - CNS depression, hypothermia, prolonged mydriasis, increased blood pressure, tachycardia, coma.

Treatment symptomatic.