Instruction for use: Crystepin

Active substance: Dihydroergocristine + Clopamide + Reserpine

ATX Code C02LA51 reserpine and diuretics combinations with other drugs

Pharmacotherapeutic group:

Sympatholytics in combinations

Diuretics in combination

The nosological classification (ICD-10)

I10 Essential (primary) hypertension

Hypertension, Arterial hypertension, Arterial hypertension crisis course, Essential Hypertension

Primary hypertension, Arterial hypertension, complications of diabetes, hypertension, The sudden increase in blood pressure, Hypertensive disorders of blood circulation, hypertensive condition, hypertensive crises, hypertension, arterial Hypertension, malignant Hypertension, Hypertonic disease, Hypertensive crisis, Hypertension, accelerated hypertension, malignant hypertension, The aggravation of hypertensive disease, Transient hypertension, Isolated systolic hypertension

I15 Secondary hypertension

Arterial hypertension, complications of diabetes, hypertension, The sudden rise in blood pressure, Hypertensive disorders of blood circulation, hypertensive condition, hypertensive crises, hypertension, arterial hypertension, malignant hypertension, Hypertensive crisis, Hypertension, accelerated hypertension, malignant hypertension, hypertensive crisis, The aggravation of hypertensive disease, Transient hypertension, hypertension, Arterial hypertension, Arterial hypertension crisis course, renovascular hypertension, symptomatic hypertension, renal hypertension, Renovascular hypertension, Symptomatic hypertension

Structure and Composition

1 tablet contains Klopamid 5 mg, 0.1 mg of reserpine and dihydroergocristine 0.58 mg; in blister 15 pcs., in box 2 of the blister.

pharmachologic effect

antihypertensive.

Blocks sympathetic impulses (mediator release and the postsynaptic membrane aktseptsiyu), which leads to reduction in vascular smooth muscle tone, reduce heart work, reduce peripheral vascular resistance; diuretic activity.

Indications

Hypertension mild to moderate severity.

Contraindications

Hypersensitivity (including to the individual components), hypokalemia, expressed human liver and kidney condition after recent myocardial infarction, depression (including history), exacerbation of peptic ulcer disease; pregnancy, lactation (should abandon breastfeeding).

Side effects

Feeling tired, muscle weakness, headache, diarrhea phenomenon, orthostatic hypotension, electrolyte disturbances (particularly hypokalemia).

Interaction

It reduces the effect of indirect anticoagulants, oral hypoglycemic agents; enhances - cardiac glycosides.

Dosing and Administration

Inside. Initially, 1 tablet per day, if necessary, the dose can be increased to 2 tablets per day; maintenance dose is 1 tablet a day every day or every other day.

Precautionary measures

Be wary appoint diabetes, gout. During treatment, it is recommended foods containing potassium (fruits, vegetables, fish); should not engage in activities that require attention (including vehicle control).

Storage conditions

In a dry, dark place at a temperature of 10-25 ° C.

Keep out of the reach of children.

shelf life

3 years.

Do not use beyond the expiration date printed on the package.