Instruction for use: Caffeine + Paracetamol + Phenylephrine + Pheniramine (Coffeinum+ Paracetamolum+ Phenylephrinum+ Pheniraminum)

Pharmacotherapeutic group:

Anilides in combinations

Stimulants in combinations

H1-antihistamines in combination

Alpha-adrenoceptor agonists in combination

Pharmacology

Pharmacological effect

Combined tool has antipyretic, analgesic, alpha adrenostimuliruyuschee, vasoconstriction and antihistamine action eliminates the symptoms of "colds". Caffeine stimulates the psychomotor centers of the brain, enhances the effect of analgesics, eliminates drowsiness and fatigue, increases physical and mental efficiency, shortens the reaction time, temporarily reduces fatigue and drowsiness. Paracetamol - NSAIDs block COX, mainly in the central nervous system, acting on pain centers and thermoregulation; It has analgesic and antipyretic effect. Phenylephrine - alpha-agonists with a mild vasoconstrictor activity. Pheniramine - blocker of H1-histamine receptors. Narrowing of vessels of the nose, eliminates swelling and hyperemia of the mucous membrane of the nasal cavity, nasopharynx and paranasal sinuses.

Indications

Symptomatic treatment of "colds" diseases, influenza, SARS (and feverish pain, rhinorrhea).

Contraindications

Hypersensitivity, simultaneous reception of others. Message containing substances that are part of the drug, concomitant use of tricyclic antidepressants, MAO inhibitors, beta-blockers, pregnancy, lactation, children's age (15 years).

Precaution

Severe coronary atherosclerosis, hypertension, hyperthyroidism, pheochromocytoma, diabetes, asthma, COPD, deficiency of glucose-6-phosphate dehydrogenase, blood diseases, congenital hyperbilirubinemia (Gilbert syndrome, Dubin-Johnson and Rotor), liver and / or kidney failure, angle-closure glaucoma, prostatic hyperplasia.

Dosage

Inside, 1-2 hours after ingestion, with a large amount of liquid. The recommended dose - 1 sachet 3-4 times a day at intervals of 4-6 hours between the intake of maximum daily dose -. 4 bags. The course of treatment - 5 days.

The contents of 1 sachet pour into a glass, pour hot water and stir until dissolved and drink (if desired, you can add sugar or honey).

Side effect. Allergic reactions: skin rash, pruritus, urticaria, angioedema.

From the nervous system: dizziness, sleep, irritability.

From the CCC: raising blood pressure, tachycardia.

From the digestive system: nausea, vomiting, epigastric pain, dry mouth, hepatotoxic effects.

From the senses: mydriasis, urinary retention, paresis of accommodation, increased intraocular pressure.

From the side of blood: anemia, thrombocytopenia, agranulocytosis, hemolytic anemia, aplastic anemia, methemoglobinemia, pancytopenia.

Other: renal toxicity (papillary necrosis), bronchospasm.

Special instructions

In cases where there is no resorption, pain resulting cake removal can reduce maceration example furatsilina solution.