Instruction for use: Bismuth subnitrate (Bismuthi subnitras)

Chemical name

Bismuth hydroxide nitrate oxide

Pharmacological group

Antiseptics and disinfectants

Gastroprotectors

Nosological classification (ICD-10)

K21.0 Gastro-oesophageal reflux with oesophagitis

Reflux gastritis, Reflux esophagitis, Erosive and ulcerative esophagitis

K25 Gastric ulcer

Helicobacter pylori, Pain syndrome in gastric ulcer, Pain syndrome in gastric ulcer and duodenal ulcer, Inflammation of the gastric mucosa, Inflammation of the gastrointestinal mucosa, Benign gastric ulcer, The disease of the stomach and duodenum, asotsiirovannoe with Helicobacter pylori, Aggravation gastroduodenita on the background of peptic ulcer, Exacerbation of peptic ulcer, The aggravation of gastric ulcer, The organic gastrointestinal disease, Peptic ulcer of the stomach and duodenum, Postoperative gastric ulcer, Recurrent ulcers, Symptomatic gastric ulcers, Chronic inflammatory disease of the upper gastrointestinal tract, associated with Helicobacter pylori, Helicobacter pylori eradication, Erosive and ulcerative lesions of the stomach, Erosive lesions of the stomach, The erosion of the gastric mucosa, Peptic ulcer disease, Stomach ulcer, Gastric lesion, Ulcerative lesions of the stomach, Symptomatic ulcers of the stomach and duodenum

K26 Duodenal Ulcer

Pain with duodenal ulcer, Pain syndrome in gastric ulcer and duodenal ulcer, The disease of the stomach and duodenum, asotsiirovannoe with Helicobacter pylori, Exacerbation of peptic ulcer, The worsening of duodenal ulcer, Peptic ulcer of the stomach and duodenum, Relapse of duodenal ulcers, Symptomatic ulcers of the stomach and duodenum, Helicobacter pylori eradication, Erosive and ulcerative lesions of the duodenum, Erosive-ulcerative lesions of duodenal ulcers associated with Helicobacter pylori, Erosive lesions of the duodenum, Duodenal ulcer, Ulcerative lesions of the duodenum]

K29 Gastritis and duodenitis

Aggravation gastroduodenita on the background of peptic ulcer, duodenitis

K52 Other noninfectious gastroenteritis and colitis

senile Bowel Syndrome, sigmoid, Gastroenteritis noninfectious, gastroenterocolitis, Colitis, Colitis non-dysenteric, Colitis noninfectious, Colitis is a chronic, Colitis is a chronic non-infectious, Local enteritis, sigmoid noninfectious, Chronic inflammatory bowel disease, Chronic inflammatory disease of the small intestine, Chronic enterocolitis, Chronic atrophic gastroenteritis, Chronic gastroenteritis, Chronic colitis, Chronic enterocolitis, Enteritis, non-infectious enteritis, Enterocolitis chronic noncommunicable, colon disease

L30.9 Dermatitis, unspecified

Allergic dermatoses complicated by a secondary bacterial infection, Anal eczema, Bacterial maturation, Varicose Eczema, Venous dermatitis, Inflammation of the skin, Inflammation of the skin upon contact with plants, Inflammatory Skin Diseases, Inflammatory skin reactions, Inflammatory processes of the skin, Hypostatic dermatitis, Fungal Eczema, Fungal dermatosis, Dermatitis, Dermatitis is stagnant, Dermatitis and eczema in the anal area, Dermatitis acute contact, Perianal dermatitis, Dermatosis, Dermatosis of the scalp, Dermatosis of psoriasis, Dermatosis with persistent itching, Dermatoses, Dermatoses itchy, Other itching dermatoses, Significant eczematous manifestations, Itching with, dermatoses, Itching eczema, True eczema, Skin reaction to insect bites,Skin itching with dermatosis, Constitutional eczema, Weeping eczema, Drowsing inflammatory skin disease, Dying Infectious-Inflammatory Skin Disease, Non-allergic dermatitis, Nummular eczema, Acute contact eczema, Acute inflammatory skin disease, Acute dermatosis, Acute severe dermatosis, Perianal dermatitis, Superficial dermatosis, Subacute Contact Eczema, Simple dermatitis, Occupational dermatitis, Psychogenic dermatosis, Bubble dermatitis of newborns, Pustular eruptions, Irritation and redness of the skin, Low-flammable eczema, Dry atrophic eczema, Dry eczema, Toxic dermatitis, Ear eczema like dermatitis, Chronic eczema, Chronic dermatosis, Chronic common dermatosis, Scaly papular dermatosis, Eczema, Eczema anal region, Eczema of the hands, Eczema Contact, Eczema lichenized, Eczema Nummular, Eczema acute, Eczema acute contact, Eczema subacute, Eczematous dermatitis, Eczema-like rashes, Ecome exogenous, Endogenous eczema, Gluteal dermatitis, Restricted itchy dermatitis

L98.4 Chronic skin ulcer, not elsewhere classified

Secondary-infected trophic ulcers, Long-lasting non-healing skin ulcer, Ulceration of the skin, Cutaneous ulcer, Wet sore ulcers, Chronic ulcers, Chronic skin ulcers, Chronic skin ulcer, Ulcers coughing, Septic ulcer

R23.4 Skin structure changes

Cracks in the skin, Erosion, Postpone, Decreased skin elasticity, Violation of keratinization processes, Age-related skin changes, Cracks in the skin, Increased dryness of the skin

Code CAS 1304-85-4

Characteristics of Bismuth subnitrate

A mixture of BiNO3 (OH) 2, BiONO3 and BiOOH, which is a white amorphous or fine crystalline powder. Virtually nerastvorim in water and alcohol, easily soluble in hydrochloric acid.

Pharmacology

Pharmacological action - anti-inflammatory, adsorptive, antacid, dermatoprotective, astringent, antimicrobial.

Coagulates proteins with the formation of dense albumin. Forms on the surface of the mucous membrane of the gastrointestinal tract a protective film of denatured proteins, has a vasoconstrictive effect, reduces the local inflammatory process, suppresses the growth and development of Helicobacter pylori. The severity of antacid effects is small.

Application of Bismuth subnitrate

Inflammatory diseases of the skin and mucous membranes (dermatitis, ulcers, erosion, eczema); gastroduodenitis, gastric ulcer and duodenal ulcer, reflux esophagitis, enteritis, colitis.

Restrictions for use

Hypersensitivity, renal failure.

Side effects

Headache, edema of the eyelids and gums, vesicles and pigmentation in the tongue, nausea, vomiting, methemoglobinemia.

Interaction

Compatible with anticholinergic, spasmolytic drugs, often used for peptic ulcer of the stomach and duodenum. With the simultaneous administration of tetracyclines, the formation of nonabsorbable complexes is possible.

Routes of administration

Inside, externally.