Instruction for use: Basiron AC
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Active substance Benzoyl peroxide
ATX code D01AE01 Bromochloro Salicylicanilide
Pharmacological group - Antiseptics and disinfectants
Composition and form of release
Gel for external use 100 g
benzoyl peroxide aqueous (in terms of benzoyl peroxide anhydrous) 2.5 g
5.0 grams
10.0 grams
auxiliary substances: methacrylic acid copolymer; poloxamer 182; Carbomer 940; glycerol; disodium edetate; docusate sodium; propylene glycol; silicon dioxide colloidal; sodium hydroxide; purified water
in tubes of LDPE for 40 g; in a pack of cardboard 1 tuba.
Description of dosage form
White homogeneous gel.
pharmachologic effect
Pharmacological action - keratolytic, antimicrobial.
Pharmacodynamics
Benzoyl peroxide exhibits antimicrobial activity against Propionibacterium acnes and Staphylococcus epidermidis. It has a keratolytic effect, improves oxygenation of tissues, inhibits the production of sebum in the sebaceous glands.
Pharmacokinetics
Penetration of benzoyl peroxide through the skin is low. The bulk of the benzoyl peroxide is converted to benzoic acid, which after absorption is introduced into the systemic circulation and rapidly excreted by the kidneys. There is no cumulation in the tissues. Dense application of Bazirone AS in therapeutic doses does not lead to side effects of systemic effects.
Indications
Acne.
Contraindications
hypersensitivity to one of the ingredients of the drug;
children under 12 years.
pregnancy and lactation
Controlled clinical trials of the drug during pregnancy and lactation were not conducted. For a long time of clinical use of Baziron AS there were no cases of toxic effects on the fetus or malformations. The use of Baziron AS gel during pregnancy and breastfeeding is possible when the intended benefit to the mother exceeds the potential risk to the fetus.
Side effects
In rare cases: local irritation - redness, peeling, dry skin, burning sensation (it is recommended to reduce the frequency of application); allergic contact dermatitis.
Dosing and Administration
Outwardly. With a gentle touch, apply the gel uniformly to the affected area 1 or 2 times a day (morning and evening) on clean, dry skin. The therapeutic effect develops after 4 weeks of treatment, a persistent improvement after a 3-month treatment.
Repeated treatment is possible after consultation with a doctor.
special instructions
Avoid getting Baziron AS gel on the mucous membranes of the eyes, mouth and nose. In case of accidental ingestion of the drug on mucous membranes, rinse thoroughly with warm water. It is not recommended simultaneous use of funds with exfoliating, drying or irritating effect (for example, products containing alcohol).
Solar and UV irradiation are not recommended, which are an additional cause of skin irritation.
storage Conditions
At a temperature not higher than 25 ° C (do not freeze).
Keep out of the reach of children.
Shelf life
gel for external use 2.5% - 3 years.
gel for external use 2.5% - 2 years.
gel for external use 5% - 3 years.
gel for external use 5% - 2 years.
gel for external use 10% - 3 years.
gel for external use 10% - 2 years.
Do not use after the expiry date printed on the package.