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Tobropt (Tobramycin) eye drops - is an antibacterial agent used in ophthalmology locally. Antibiotic of the aminoglycoside group, which has a wide spectrum of action, for the treatment of infections of the eyes and its appendages.
A broad-spectrum antibiotic from the aminoglycoside group for topical application in ophthalmology. It acts bacteriostatically, blocking the 30S subunit of the ribosome and disrupting protein synthesis.
Highly active against coagulase-negative, coagulase-positive staphylococci and penicillin-resistant strains (including Staphylococcus epidermidis, Staphylococcus aureus), certain types of streptococci (including beta-hemolytic strains from group A, some non-haemolytic strains, Streptococcus pneumoniae ), Pseudomonas aeruginosa, indole-positive and indole-negative Proteus spp. (including Proteus mirabilis, Proteus vulgaris), Escherichia coli, Klebsiella pneumoniae, Haemophilias influenzae, Haemophilus aegyptius, Enterobacter aerogenes, Moraxella lacunata, Morganella morganii, Acinetobacter calcoaceticus, Neisseria spp. (including Neisseria gonorrhoeae).
Some gentamicin-resistant strains retain high sensitivity to tobramycin.
It is not effective against most strains of streptococcus group D.
Tobramycin penetrates well through the BBB. Systemic absorption during instillation into the conjunctival sac is insignificant.
When instilled into the conjunctival sac, aminoglycosides are found in the therapeutic concentration in the corneal stroma, the anterior chamber, the vitreous humor for 6 hours. Aminoglycosides are not metabolized and are excreted by the kidneys.
The traptrop is for local use only.
The bottle must be closed after each use. To maintain the sterility of the solution, the tip of the pipette should not touch the eye.
Prolonged use of the drug may lead to increased growth of non-susceptible microorganisms (including fungi). It is recommended to sow after the end of treatment if the clinical result is unsatisfactory.
Patients using hard contact lenses should use eye drops only after removing contact lenses. Lenses can be worn 15 minutes after instillation of the drug. During the treatment period, you can not wear soft contact lenses.
With the development of allergic reactions, the drug should be discontinued.
Shake the bottle before use.
Impact on the ability to drive vehicles and manage mechanisms
The use of the drug does not cause increased fatigue and visual impairment and, accordingly, does not affect the ability to drive vehicles and control mechanisms. Patients who temporarily lose visual clarity after application are advised not to drive or work with complicated equipment immediately after instillation of the drug.
The drug should be applied topically 1 drop every 4 hours.
When acute infections can be repeated instillation every 30 minutes or 1 hour.
With a mild infectious process, the drug is instilled in 1-2 drops in the conjunctival sac of the affected eye (or eyes) every 4 hours.
In acute severe infectious process (endophthalmitis), the drug is instilled into the conjunctival sac every 30-60 minutes, as the inflammation decreases, the incidence of instillation is reduced.
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