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Instructions

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Instruction for use: Arutimol

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Active substance Timolol

ATX Code S01ED01 Timolol

Pharmacotherapeutic group:

Beta-blockers

Ophthalmic tools

The nosological classification (ICD-10)

H40 Glaucoma

glaucoma intervention., Afakicheskaya glaucoma, narrow-angle glaucoma, Chronic glaucoma, Chronic open-angle glaucoma, Wide-angle glaucoma

H40.1 Primary open-angle glaucoma

open-angle glaucoma, Open-angle glaucoma, Primary glaucoma, pseudoexfoliation glaucoma, Elevated IOP

H40.2 Primary angle-closure glaucoma

closure Glaucoma, Glaucoma with a narrow angle of anterior chamber, Angle-closure glaucoma, Acute angle-closure glaucoma, An acute attack of angle-closure glaucoma, Elevated intraocular pressure angle-closure glaucoma, Chronic angle-closure glaucoma

Structure and Composition

Eye drops 0.25 ml of 1%

timolol maleate 3.42 mg

(Corresponds to 2.5 mg of timolol)

Excipients: Benzalkonium chloride - 0.03 mg (as a preservative); povidone; edetate disodium dihydrate; sodium dihydrogen phosphate dihydrate; sodium monohydrogen phosphate dodecahydrate; water for injections

in vials-droppers of 5 ml; in box 1 bottle.

0.5% eye drops 1 ml

timolol maleate 6.83 mg

(Corresponding to 5 mg timolol)

Excipients: Benzalkonium chloride - 0.03 mg (as a preservative); povidone; edetate disodium dihydrate; sodium dihydrogen phosphate dihydrate; sodium monohydrogen phosphate dodecahydrate; water for injections

in vials-droppers of 5 ml; in box 1 bottle.

pharmachologic effect

antiglaucoma.

Beta-adrenoceptor blocking and reduces the secretion of aqueous humor, reducing the intraocular pressure.

Pharmacokinetics

Well absorbed by the retina and the nasal mucosa, it is excreted in the urine.

Clinical pharmacology

In topical application the intraocular pressure decreases after 20 minutes, the maximum effect - in 2-3 hours duration - 24 hours.

Indications

Glaucoma (all forms).

Contraindications

Hypersensitivity, severe obstructive airways disease, sinus bradycardia, AV block, heart failure, severe allergic rhinitis.

Pregnancy and breast-feeding

When used in the I trimester of pregnancy must be weighed the possible benefits and potential risk.

Side effects

Nausea, diarrhea, weakness and fatigue, disorientation, hallucinations, respiratory failure, bradyarrhythmia, hypotension, bronchospasm, reduction of tear secretion, blepharitis, conjunctivitis, keratitis, allergic reactions, tachyphylaxis.

Interaction

Compatible with miotocs and carbonic anhydrase inhibitors.

Dosing and Administration

Kongungualno. At the beginning of therapy instilled 1 drop preparation Arutimol 0.25 or 0.5% in the diseased eye two times a day.

If the intraocular pressure is normal with regular use, the dosage should be limited to 1 times daily 1 drop of the drug.

Arutimol treatment is carried out, as a rule, for a long time. Suspension or dosage change be made only by order of the physician.

Storage conditions

In the dark place at a temperature no higher than 25 C.

Keep out of the reach of children.

Shelf-life

3 years. After opening the vial 6 weeks.

Do not use beyond the expiration date printed on the package.

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