Instruction for use: Anandron
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ATX code L02BB02 Nilutamide
Pharmacological group
Androgens, antiandrogens
Antineoplastic hormonal agents and hormone antagonists
Nosological classification (ICD-10)
C61 Malignant neoplasm of prostate
Adenocarcinoma of the prostate, Hormone-dependent prostate cancer, Hormone-Resistant Prostate Cancer, Malignant tumor of prostate, Malignant neoplasm of prostate, Carcinoma of the prostate, Locally-distributed non-metastatic prostate cancer, Locally advanced prostate cancer, Locally spread prostate cancer, Metastatic prostatic carcinoma, Metastatic prostate cancer, Metastatic hormone-resistant prostate cancer, Non-metastatic prostate cancer, Incompatible prostate cancer, Prostate Cancer, Prostate cancer, Common prostate cancer, Testosterone-Depot Prostate Cancer
Composition and form of release
1 tablet contains nilutamide 50 mg; In a blister of 15 pcs., In a box of 6 blisters.
pharmachologic effect
Pharmacological action - antiandrogenic, antitumor.
It blocks the androgen receptors.
Indications
Metastatic prostate cancer.
Contraindications
Hypersensitivity, anemia, impaired liver function.
Side effects
Nausea, vomiting, disruption of accommodation, interstitial pulmonary syndrome, anemia.
Interaction
Strengthens the effects of propranolol, chlordiazepoxide, diazepam, theophylline, blocking their microsomal oxidation; Is incompatible with alcohol (antabuse effect).
Dosing and Administration
Inside, 300 mg / day for 4 weeks, then maintenance therapy - 150 mg / day.
Precautionary measures
Treatment should be discontinued if symptoms of pulmonary involvement, unexplained abdominal pain, signs of jaundice, increased serum transaminase levels (3-fold compared to normal), or a decrease in hemoglobin. It is necessary to refrain from drinking and driving.
storage Conditions
At a temperature not exceeding 25 ° C.
Keep out of the reach of children.
Shelf life of Anandron
3 years.
Do not use after the expiry date printed on the package.