Instruction for use: Acenocumarol

Dosage form: tablets

Active substance: Acenocoumarolum

ATX

B01AA07 Acenocumarol

Pharmacological groups

Anticoagulants

The nosological classification (ICD-10)

I21 Acute myocardial infarction: Myocardial infarction in the acute phase; Acute Myocardial Infarction; Myocardial infarction with pathologic Q wave and without; Myocardial infarction complicated by cardiogenic shock; Infarction left ventricular; Transmural myocardial infarction; Myocardial infarction netransmuralny (subendocardial); Netransmuralny myocardial infarction; Subendocardial myocardial infarction; The acute phase of myocardial infarction; Acute myocardial infarction;Sub-acute phase of myocardial infarction; Subacute phase of myocardial infarction; Thrombosis of the coronary arteries (the arteries); Threatened myocardial infarction; Myocardial infarction without Q wave

I74 Embolism and arterial thrombosis: Thrombosis of effort (stress); Arterial thrombosis; Arteriothrombosis; Subacute and chronic arterial thrombosis; Subacute thrombosis of peripheral arteries; Postoperative thrombosis; Vascular thrombosis; Vascular embolism; Thrombosis of aortocoronary shunt; Arterial thrombosis; Thrombosis of arteries; Coronary artery thrombosis; Coronary thrombosis; Thrombosis of blood vessels; Thrombosis with ischemic stroke; Thrombosis with general surgical operations; Thrombosis in Oncology Operations; Vascular thrombosis; Thrombus formation in the postoperative period; Thrombotic complications; Thromboembolic diseases; Thromboembolic syndrome; Thromboembolic complication in the postoperative period; Thromboembolism of arteries; Partial vascular thrombosis; Embolism; Embolism of arteries

I82 Embolism and thrombosis of other veins: Recurrent venous thrombosis; Postoperative thrombosis; Venous thrombosis; Acute venous thromboembolism; Recurrent vein thrombosis; Venous thrombosis; Thrombosis of veins of internal organs; Venous thrombosis; Deep vein thrombosis; Thrombosis of blood vessels; Vascular thrombosis; Thrombosis of veins; Deep vein thrombosis; Thromboembolic diseases; Thromboembolism of veins; Severe venous thrombosis; Embolism; Embolism of veins; Thromboembolic complications

R07.2 Pain in the heart: neuroses of the heart; Myocardial ischemic pain; Pain syndrome in myocardial infarction; cardialgia; cardioneurosis; Cardiac syndrome; Pain in cardiac patients; Cardialgia on background dyshormonal myocardial dystrophy; Functional cardialgia; Psevdostenokardiya; pericardial pain

Composition and release form

Acenocoumarol 4 mg

In bottles of 60 pcs .; In the box 1 bottle.

Pharmachologic effect

Mode of action - Anticoagulant.

The inhibition of the synthesis of factors II, VII, IX and X.

Pharmacokinetics

Well absorbed in the gastrointestinal tract, Cmax in the blood - 1-8 hours after ingestion. The association with blood plasma albumins is over 90%.

Clinical Pharmacology

Hypoprothrombinemia occurs 36-48 hours after ingestion and persists for several days.

Indications for Acenocumarol

Phlebothrombosis, pulmonary embolism, coronary thrombosis (prophylaxis).

Contraindications

Hemorrhagic diathesis, intracranial hemorrhage, peptic ulcer of stomach and duodenum, hepatic insufficiency.

Pregnancy and breast-feeding

Contraindicated in pregnancy.

Side effects

Dyspepsia (nausea, vomiting, diarrhea); bleeding.

Dosing and Administration

Inside, squeezed a small amount of fluid, once, on the first day of 6-8 mg, then 4 mg / day under the control of PV (prothrombin index should be within 2-3.5). The frequency of admission is 1 time per day at the same time.

Storage conditions of the drug Acenocumarol

In a dry place, at a temperature of 5-14 ° C.

Keep out of the reach of children.

The shelf life of the drug Acenocumarol

3 years.

Do not use beyond the expiration date printed on the package.