Proxibarbal - Active Substances. Instruction and Application, Dosage

Name: Proxibarbal

The Latin name of the substance Proxibarbal

Proxibarbalum (genus Proxibarbali)

Chemical name: 5- (2-hydroxypropyl) -5- (2-propenyl) -2,4,6 (1H, 3H, 5H) -pyrimidinetrione

Formula - C10H14N2O4

Therapeutic substances Proxibarbal - anxiolytics

The nosological classification (ICD-10)

G43 Migraine
K25 Gastric ulcer
K26 Duodenal Ulcer
N94.3 syndrome premenstrual tension
N95.1 menopausal and menopausal status of women
R51 Headache

CAS code - 2537-29-3

Characteristics substance Proxibarbal
The white crystalline powder and odorless. Slightly soluble in water, soluble in alcohol, ether, chloroform and methylene chloride.

PharmacologyMode of action - a sedative, tranquilizing.

It regulates the function of the reticular formation, the hypothalamus and the autonomic nervous system. It inhibits the action of neurotransmitters excitement intensifies the effects of GABA. Reduces neurovegetative disorders accompanying psychosomatic disorders. It eliminates anxiety, restlessness, irritability, vasomotor headache (including migraine). It has a regulating effect with autonomic dysfunction. Stabilizing effect on the CNS after 4-10 days after initiation of therapy.

When ingestion rapidly and completely absorbed from the gastrointestinal tract. Cmah reached after 30 minutes. Easily it passes through the blood-tissue barriers, including GEB. It is metabolized in the liver. Report mostly kidneys.

Application of the substance Proxibarbal

Headache vasomotor origin, migraine, neurosis, psychopathy, vegetative lability somatic disorders, premenstrual syndrome, menopausal disorders, gastric ulcer and duodenal ulcer (in the complex therapy).

Contraindications

Hypersensitivity, kidney and liver failure, pregnancy, breast-feeding.

Restrictions of application of Proxibarbal

Children under 18 years of age (safety and efficacy have not been determined).

Pregnancy and breast-feeding
Contraindicated during pregnancy. At the time of treatment should stop breastfeeding.

Side effects of Proxibarbal substance 

Dizziness, somnolence, dyspepsia, allergic reactions; long-term use - addiction and drug dependence.

Interaction

It enhances the effects of (each) other sedatives (including alcohol).

Overdose of Proxibarbal

In case of overdose possible drowsiness.

Dosing and Administration of Proxibarbal

Inside, 50-100 mg 3 times a day for 4-6 weeks.

Precautions substance Proxibarbal
Be wary appoint elderly and debilitated patients, children with depression. It should not be used in combination with other drugs sedatives.

Should not be used during the drivers of vehicles and people skills relate to the high concentration of attention.

Trading names of drugs with Proxibarbal working substance

Trade Name Index 

Ipronal