Neurotrophins and Gene therapy

What are the functions of neurotrophins? How do they affect the nerve cells in stressful situations? In some pathological conditions of neurotrophic factors are used as a therapeutic agent?

The nerve cells in the body are at the opposite effect of various external factors that promote the survival, development and health of nerve cells and the factors which lead to its deterioration and degeneration conditions. The latter is very often occur during various pathological conditions, such as nervous system diseases, strokes, trauma, and so forth. After these pathological conditions are often used Cerebrolisine, Neuromidine, Meldonium, Semax.

In our body, there are factors that help to stimulate the nerve cells for the active work, to fight. Such factors may include the so-called "neurotrophins" - very hard for the past 50 years, we studied a group of factors that are secreted by acting on nerve cells outside.

The effect of these factors is quite diverse. They are necessary for the formation of nerve connections in the process of development in ontogenesis, to form synaptic contacts to simulate the activity of nerve cells to the correct formation of connections with surrounding cells and much more.