Neuroleptics, Antipsychotics. Part 6

It is time to continue to acquaint you with the contents of the mental magic suitcase. Believe me, there is a lot of interesting and in addition to neuroleptics, but it just started to talk about them, it is necessary to read out all (or almost all) of the list. Again, a large psychiatry without this class of drugs does: think of how psychiatric patients lived before the advent of neuroleptics.

Olanzapine. Zyprexa, Egolanza, Zalasta, Parnasan - just as it is generic not only called names. To distinguish it from Risperidone is that if the first prefers to act first on hallucinations, and the second - already on nonsense, here everything is just the opposite. Favorite target of Olanzapine - it's just crazy designs. And because all sorts of conspiracy theories, reinforced belief in the evil machinations of the neighbors, the total control of Zog and other entertaining constructing sick mind, he crushes fascinated with the bulldozer mania. In addition, it is not bad effect on the phenomenon of motor and ideational automatism - that is, such as it seems to the patient that his thoughts and actions of someone manages, or his thoughts are open to all associates.

By the way, with mania, Olanzapine is also doing well - apparently due to its ability to jump ideas and went hawking thinking, as well as to undermine the view of your own drop dead; mood itself (in the case of mania - the radiant) it does not directly affect.

In addition, Olanzapine reduces the appearance of several so-called negative symptoms of schizophrenia. The same quality, although to a lesser extent, has Risperidone. It can be used in microdozes for obsessive-compulsive disorder. You can try Phenibut.

All this, coupled with a pretty good tolerability, make an attractive drug for the treatment - especially in the beginning when the disease only manifests. Again, the antipsychotic olanzapine syndrome rarely cries - even less than risperidone. But ... Side effects he still has. And one of the most frequent and unpleasant - a set of weights. Especially when its reception in high doses. Less frequently (and less than risperidone) causes an increase in the drug blood levels of prolactin (and associated male gynecomastia, breast augmentation and isolating from it in women and other unpleasant effects). The risk of diabetes is also present, but also less than that of risperidone.

Amisulpride. Solian aka limipranil. In contrast, olanzapine, stronger effect on hallucinations than delirium. Although paranoid (ie one in which hallucinations and delusions are interrelated and combined) symptoms crushes too bad. In terms of effects on hallucinations superior and risperidone, and in some cases more effective than haloperidol, which, as I said, for decades has been the benchmark in this regard.

Another sphere of influence - negative symptoms, emotional and volitional defect. First of all - in schizophrenic patients. Therefore Solian often given in cases where delusions and hallucinations, like, little or practically no, but the emotional and volitional defect had time to develop, and determine the lion's share of the picture of the disease.

Sometimes used Solian and severe depression - in combination with antidepressants, naturally. It is because of his ability to stir up the emotional and volitional and act on the ideas of worthlessness and meaninglessness so drag out a miserable existence. He found the use and obsessive-compulsive disorder - although in microdozes as olanzapine.

Side effects - neuroleptic syndrome that amisulpride is less than haloperidol, but just as often, if not more often, compared to risperidone. The level of prolactin in the blood Solian may also increase, and it happens more often than in the case of risperidone, and the effect of this act all the time, while there is its receiving.