Flucostat – General information

Why take Flucostat?

Systemic effects

Unlike the local means of "thrush", produced in the form of creams, suppositories or vaginal capsules Flucostat acts inside the body and eliminates the Candida fungus not only from the surface of the vaginal mucosa, but throughout its thickness, including microfolds, and with external genital organs. Flucostat eliminate pathogens "thrush", and also other possible habitat of the fungus, for example, in the gut and oral cavity, employees often reservoirs Candida spp, -. thereby minimizing the risk of re-exacerbation of disease after treatment.

Accuracy

Due to its highly specific properties of the drug, "thrush" Flucostat operates solely on fungal cells, and does not suppress the vital activity of bacteria that are members of the normal flora of the gastrointestinal tract and the vagina. Receiving Flucostat does not lead to the development of dysbiosis.

Quick results

Fluconazole (the active ingredient of the drug Flucostat) can quickly eliminate the symptoms of acute uncomplicated "thrush", characteristic of him:

achievement of maximum concentrations within 2 hours after administration;
rapid relief of the state - the average time of the beginning of the disappearance of symptoms for 24 hours;
rapid resolution of symptoms of the disease - the average time of complete disappearance of symptoms is 2 days.

To eliminate the disease symptoms in the majority of women with acute "thrush" just enough to receive one capsule Flucostat 150 mg.

Easement

Flucostat Treatment is often more convenient and comfortable, in comparison with vaginal (local) agents against "thrush":

Unlike candles Flucostat can be used immediately at the first manifestation of unpleasant symptoms, "thrush";
Start treatment at any day of the menstrual cycle, including monthly.
Flucostat capsule can be taken at any time - day or night.
The drug can be taken regardless of dietary regime - fasting, during or after meals.
The drug is simple and easy enough to get the capsule out of the blister and swallow it, washed down with the required amount of water.

The favorable safety profile

Flucostat can be taken with any method of contraception. Unlike local medicines "thrush", with oil-based Flucostat not able to break the integrity of latex contraceptive (condom or diaphragm). It is also confirmed that no oral fluconazole lowers estradiol - a main component of oral hormonal contraceptives, and hence does not reduce their contraceptive properties.

Quality

Flucostat produced according to strict European EU GMP quality standards at the first Russian company included in the European EudraGMP data base.

Manufacturer Flucostat constantly improved and checks the quality of production and raw ingredients in accordance with the latest technological advances.

Bioequivalence Flucostat original fluconazole proved and confirmed by clinical studies.

Reliability Flucostat action checked a long history of its use, as well as the positive experience of the use of millions of women in Russia. Please pay attention to Bronhalamin.

01.Flucostat
Flucostat - modern antifungal broad-spectrum, highly active against Candida genus fungi, pathogens "thrush". The active substance is fluconazole Flucostat, thanks to which is achieved therapeutic results when using the drug.

02.fluconazole
Fluconazole is recognized throughout the world gynecologists "gold standard" in the treatment of vulvovaginal candidiasis ("thrush"). Its efficacy and safety are proven by numerous studies conducted in various countries around the world. Currently, fluconazole is the only antifungal agent for oral administration, which is approved by WHO (World Health Organization) and CDC (Center for Disease Control and Prevention of sexually transmitted infections, USA) for the treatment of "thrush".

03.Quality
Manufacturer Flucostat company "Otisifarm" is constantly being improved and checks the quality of production and raw ingredients in accordance with the latest technological advances. The result of this was the acquisition in 2009 production site preparation Flucostat European certificate of GMP (certificate š ZV / LV / 2009 / 001H), testifying to its compliance with international quality standards. The company "Otisifarm" is currently the only Russian company registered in the European database.

How does Flucostat acts?
The fungus genus of Candida, causing "thrush", is always present in their natural reservoirs: the oral cavity and pharynx, in the mucous membranes of the gastrointestinal and urogenital tracts. Each fungal cell is an independent organism, within which there is a chain of "building" process, aimed at its livelihood and implemented with the help of special enzymes.

Therapeutic effect Flucostat

Flucostat blocks one of these enzymes, hindering the "building" process within the fungal cell. Caught without the necessary components, a cell ceases to multiply, grow and eventually dies. Thus, Flucostat not only inhibits the growth and multiplication of fungal cells, but also leads to their death, thus eliminating the root cause of "thrush".

From inside the body Flucostat creates and maintains a high concentration of active substance in almost all tissues of the organism and environments, including any possible Flucostat reservoirs provides a therapeutic fluconazole concentrations not only in the walls of the vagina, but also in vaginal secretions. Created concentration of the drug from yeast several times higher than the concentration required to suppress the life and death of fungus Candida albicans cells. This achieves the reliability of the therapeutic effect and minimize the risk of recurrence, "thrush" Flucostat after treatment.

What is thrush?

"Thrush" - so in common parlance is called vaginal candidiasis - mucosal disease of the female reproductive organs due to overgrowth of yeast fungi genus Candida. "Thrush" is not a disease, sexually transmitted. Vaginal candidiasis in women can occur regardless of the presence or absence of sexual activity.

"Thrush" - a common disease and is familiar to almost every woman. According to some estimates, about 75% 1 of women suffer at least one episode of "thrush", and 50% of them stated at least one relapse (second episode).

Fungi of the genus Candida Natural reservoirs

This type of fungus present in the body most healthy people - on the skin, the mucous membranes of the gastrointestinal (mouth, intestine) and urogenital tracts. Under normal circumstances, Candida does not manifest itself and "living in harmony" with other members of the normal microflora of the human body. For example, Candida fungi, are often part of the normal microflora in the vagina, and in small amounts they do not harm. However, under the influence of various unfavorable factors the delicate balance of microflora can be broken, thus triggering increased growth and reproduction of Candida. In turn, this may lead to the development of symptoms of vaginal candidiasis.

Symptoms of thrush
There are several signs of "thrush" in women. You may experience any one or more of them simultaneously.

Itching in the crotch area
Vaginal discharge
Burning and pain when urinating
Pain and discomfort during intimacy

It is important to remember that these signs of "thrush" in women as discharge and itching can be caused not only by vaginal candidiasis, but also a number of other sexual infections. The most commonly observed symptoms of the above for the following diseases: bacterial vaginosis, candidiasis ( "thrush"), trichomoniasis.
TEST FOR POSSIBLE cause of vaginal discharge
In order to establish the reasons for discharge, pass this test. However, remember that the results are only preliminary. Put the correct diagnosis, adequate therapy, to establish the duration of treatment and monitor its effectiveness may only doctor.

Causes of thrush and risk factors

The reasons why some adult women are more likely to develop vaginal candidiasis, to date not been fully explored. It is only important to understand that "thrush" - it is always a consequence of the disease, - a consequence of any external factors impacting on the body, or a consequence of the internal changes taking place in it.

Reducing the body's defenses
If your body is weak or you are constantly experiencing stress, this may adversely affect the state of the immune system that normally prevents the development of many infectious diseases. This means that your body is no longer able to so effectively with various pathogens, including pathogens, "thrush". Lowered immunity may contribute to chronic wasting disease (extensive burns, trauma, anemia, etc..), The deficit in the diet of protein, vitamins and several other states. In some cases, lower immunity and can certain medications, such as for example, steroids (hormones) or immunosuppressants, as well as several methods of treatment - radiotherapy or chemotherapy. Helping patients who have had an organ transplant or cancer patients, these medications at the same time increase the likelihood of their Candida infection.

Pregnancy
"Thrush" in pregnancy there are two to three times more often than in the female population as a whole. It was from the onset of pregnancy, many women are faced with the problem of "thrush" for the first time. This is due to the fact that during the pregnancy hormone levels in a woman's body changes, which is reflected in the condition of the vaginal mucosa. These changes create ideal conditions for the growth and reproduction of Candida fungi in it and, therefore, contribute to the development of symptoms, "thrush".

Infection of the intestine

The yeast Candida species are quite common inhabitants of the gastrointestinal tract. At 10-25% observed absolutely healthy asymptomatic carriage of fungi in the oral cavity, and have 65-80% - in the intestine. Failure to comply with the rules of hygiene, mushrooms from the bowel can infect the mucous membrane of the vagina. From the anus, they can enter the vagina, if after a bowel movement movements wiped from back to front, or during intimate hygiene water jet and hand movements will be directed to the same same way. Fungi from the gastrointestinal tract may be a factor contributing to relapse "thrush".

Usage of Antibiotics
Antibiotics - it's drugs, which suppress the vital activity of bacteria that are the cause of many infectious diseases. Most often they are used in the treatment of pneumonia, bronchitis, tonsillitis, cystitis and other diseases. However, besides suppressing life activity of pathogenic microorganisms, antibiotics also leads to the death of the bacteria which are part of the normal flora of the human body, including vaginal microflora. For example, antibiotics cause the death of lactobacilli that normally restrain excessive growth and reproduction of fungi in the genus Candida vagina. Being "without control", the mushrooms begin to behave aggressively and vigorously proliferate, causing the development of symptoms of "thrush".

Diabetes
When diabetes is marked high level of glucose (sugar), not only in the blood and urine, but also in the cells of the vaginal epithelium and mucous secretions. The increased sugar content contributes to a change in the pH of the vaginal secretion. The normal pH of vaginal secretion within the range of 3.8 to 4.2, i.e. It is acidic. In diabetes the pH of the vaginal secretion becomes more acidic, which favors excessive growth and reproduction of yeast fungi of the genus Candida. That's why women with diabetes are more prone to the development of "thrush". Please be aware that the risk of candidiasis is also increased in a number of other endocrine disorders (thyroid gland, adrenal glands, decreased ovarian function, and others.).

Damage to tissues of the vagina

Any damage to the external genitalia, resulting, for example, as a result of friction too tight or uncomfortable underwear, bath towel to use hard or during sexual intercourse, increase the risk of "thrush".

Among the other factors contributing to the development of the uro-genital candidiasis, it should be noted: frequent change of sexual partners, use of tampons, spermicidal foams, perfume soap, bath foam, intimate sprays and deodorants, overreliance vaginal showers and syringing, especially with the addition of chemicals . All of them are able to change the acidity of the vaginal secretions, and also cause damage to delicate tissues of the vagina.

Admission combined contraceptive

Combined contraceptives contain in their composition hormones - estrogen and progesterone, which change the level of its own hormones in a woman's body. High doses of progesterone in the blood can have a negative effect on the immune system, and increase estrogen levels - it leads to the accumulation in the cells of the vaginal mucosa of glycogen, which is a good breeding ground for fungi. Thus, the amount of Candida in the vagina is directly dependent on the level of these hormones. That is why oral contraceptives containing even minimal doses of hormones, increases the risk of "thrush" in adult women.

Symptoms "thrush" in women may increase the week before menstruation, which is also due to changes in estrogen levels. Thus, the hormonal changes that occur in women before menstruation, during menopause may also be a possible cause of the uro-genital candidiasis in some of them.

Prolonged wearing of close, tight-fitting clothes
Fungi of the genus Candida loves heat and moisture. Such conditions are created in the crotch with a constant wearing tight fitting underwear made of synthetic fabrics - nylon panties kombi-dress, tights and OE fabrics from which they are made, bad leak air and allow the skin to "breathe", creating a sort of "greenhouse effect". Fever stimulates sweating. However, due to the disturbed air moisture does not evaporate and remains on the skin surface. In addition, we should not forget that close underwear as a result of friction can cause the formation of micro traumas.

Forms of thrush

Uncomplicated form
It occurs in 95% of cases and usually occurs in women with normal immunity appears sharp and characterized by mild to moderately severe clinical signs of disease. This form of "thrush" characteristic, including for new-onset disease episode.
Episodic or infrequent exacerbations (at least 4 per year)
Mild to moderate symptoms
Against the background of normal immunity or absence of other co-morbidities

Complicated form
It is quite rare, characterized by frequent repeated exacerbations with severe signs of "thrush"; This form of the disease usually occurs in debilitated, malnourished women, diabetes mellitus, or general decline in immunity).
Recurrences are more than 4 episodes per year
Severe symptoms
Against the background of diabetes, exhaustion, reduced immunity during pregnancy.

How to treat thrush

And whether it is necessary to cure thrush infection?

The bad habit of many - to hide our heads in the sand and waving his hand to the disease, in the hope that it in any way be held by itself. Unfortunately, "thrush" does not pass on their own! Attempts to overcome the "yeast" by the frequent hygiene, cleaning the douches and bring only temporary relief, and the state of masking the symptoms. However, this is not an indication that the disease has passed, since it is not eliminated the main cause of the disease - a fungus Candida albicans, which is excessive multiplication and leads to the development of symptoms of vaginal candidiasis. Lull means "thrush" only temporarily receded, and its causative agent of hiding for a short time to remind about themselves with renewed vigor in the most unexpected moment. Without adequate treatment, aimed at eliminating the real cause of the disease, "thrush" is able to go into a chronic relapsing form, with frequent repeated exacerbations during the year. To cope with this form of the disease is much more complicated, it may take a lot of time and effort. To run the situation and avoid the development of complications must be confirmed as soon as possible presumptive diagnosis and start the right treatment, "thrush" in the first episode of the disease, as well as the occasional case of aggravation.

Stages of treatment "thrush" in women

1 True diagnosis
2 Selection of the optimal therapy agents capable of providing the full elimination of fungi of the genus Candida not only genital mucosa, but also in other places of their possible habitats in the body
3 Laboratory confirmation of the destruction of the pathogen and its absence after treatment
4 Compliance measures aimed at preventing a recurrence of the disease and maintaining a healthy balance of microflora in the intimate feminine.

Methods for the treatment of thrush

Folk remedies
"Thrush" is known since ancient times. Even then, she brought a little trouble not the fair sex. Since then, than just not trying to fight the disease unfortunate women. Some recipes "folk" medicine came before us. Some of them can be found in women's forums dedicated to discussing the issue and "thrush" treatment at home: douching decoction of the bark of oaks, chamomile flowers, marigold, garlic and other plants; use baking soda solution, intravaginal administration tampon with yogurt and many others. Treatment of "thrush" folk remedies based on the change in the pH of the vaginal environment and establishing therein conditions unfavorable to the growth and reproduction of fungal cells. In addition to the inconvenience of their preparation and application, for the most part, folk remedies for "thrush" in any way are active only at the time of direct use in the treatment of genital tract mucosa. They are not fixed and held on the surface of the vagina, and therefore does not have a prolonged action. Among other things operate traditional medicine only in the most superficial layers of the mucous membrane of the vagina, while the fungus causing "thrush" can reproduce not only on the surface but also in the deeper layers, and reside in other natural reservoirs - by oral mucosa or bowel canvases. Therefore, traditional medicines from "thrush", prepared by women at home, can only temporarily relieve the condition, reduce the severity of symptoms, but can not eliminate the cause of the disease, and, as a consequence, and to solve the problem. By the way, do not feel at all the recipes of traditional medicine, because many of them have for themselves no evidence that could confirm their effectiveness. You do not need to take risks and experiment. A more reasonable when the first symptoms of disease immediately consult a doctor and qualified medical care!

MEDICINES
When set and confirm the diagnosis of "thrush", experts use special group of medicines called "antifungals". The very definition of the profile says their actions - have anti-fungal properties inhibit the growth, division, multiplication and cause the death of fungal cells, including fungi genus Candida, which cause "thrush". The active ingredient of such preparations are molecules designed and synthesized through advances in science, medicine and pharmacy. All of them have passed clinical trials and proven antifungal activity in vitro, and also confirmed the efficacy and safety in animal and human studies. A variety of antifungal drugs "thrush" differ from each other in the active agent, the breadth of the spectrum of antifungal activity, antifungal activity and strength of the release form. Many of them are included in clinical guidelines, both domestic and international, protocols and standards of care.

That they are guided by the doctors prescribed treatment. In some cases, a specialist may prescribe a combined preparation, which in addition to the anti-fungal components are present and other molecules. Typically, such agents are recommended for mixed pathology caused by bacterial and fungal flora.

By way of the use of antifungal drugs by women from "thrush" are divided into two major groups:
1) applied topically (local action of drugs) - are inserted vaginally;
2) used inside (systemic effects of drugs) - are taken orally.

Each group of products has its own characteristics, which will be discussed below. The main thing to remember, no matter what the drug was prescribed by a doctor, it should only purchase at the pharmacy. This guarantees the quality, and hence the success of the treatment.

The preparations of local action
The traditional form of the release of many gynecological drugs are vaginal suppositories. "Thrush" in this case is no exception. In the treatment of vaginal candidiasis is also quite common to use the funds introduced into the vagina - vaginal tablets, creams, ovules or candles from "thrush". Their advantages are: the action purely on location problems, a low level of systemic side effects on the body and a relatively good therapeutic results. However, in the process of melting under the effect of human body temperature, vaginal agents can not provide a uniform distribution of active substance throughout the mucosal surfaces. This creates an environment conducive to the preservation of reservoirs of infection, predisposing to relapse of the disease.

Also local drugs acting locally operate only on the mucosal surface and can not cope with a fungus that lives on not only the surface of the vaginal mucosa, but also in the deeper layers of it.

In addition, vaginal agents do not eliminate the fungal cells with the external female genitalia, referred to as the vulva (vaginal vestibule, large and small labia, perineal skin and pubic area). And even more so they can not have any effect on the fungi of the genus Candida, live on the mucous membranes of the mouth and intestines. Surviving fungi can be one of the possible causes of repeated "thrush" episodes .1

That is why often the treatment of "thrush" local action of the drug effect of their application is not sufficiently resistant and reliable results necessary to use combination therapy with simultaneous application immediately 3 funds: vaginal suppositories, tablets for oral administration and external anti-fungal cream. In addition, you should know about a number of possible purely technical inconveniences associated with the use of means of local action.

DISADVANTAGES AND LIMITATIONS OF USE DRUGS LOCAL ACTION

DEPENDENCE OF PHASE OF WOMEN'S CYCLE

Treatment creams, vaginal tablets and candles against "thrush" is recommended only after the end of menstruation, while the main symptoms of the disease (the painful itching and burning sensation) or appear significantly worse just a few days before it starts. This is due to increased growth and reproduction of Candida species during the period of the cycle. Therefore it is better if treatment is initiated in these days, and the therapeutic effect of the drugs will be maintained and during menstruation.

DISCOMFORT

The introduction of the drug into the vagina requires adherence to certain rules of personal hygiene (a minimum of hand washing before and after the installation of candles). For many women, vaginal self administration of the drug with an applicator or a finger is associated with unpleasant sensations and discomfort. Already being inside, candles against "thrush" can cause side effects such as a local irritant.

Under the influence of the human body temperature, the consistency of creams and suppositories from "thrush" often becomes a liquid. They may spread, smearing the bottom and / or linen. Given this fact, intravaginal agents are recommended for the night.

LIMITATION OF SEXUAL ACTIVITY
Intravaginal drug disposition implies the restriction of sexual activity, which can create a certain tension in the relationship with the partner.

Reducing the Effects of contraception
Oil-based creams and candles against "thrush" is able to damage the structure of latex barrier contraceptives (condoms and diaphragms) and, accordingly, reduce its contraceptive effect.

Incompatibility with a tampon
In the treatment of vaginal preparations of "thrush" is not desirable to simultaneously use tampons. Their surface is able to absorb part of the drug, reducing the effectiveness of the treatment.

Duration of treatment
The course of treatment "thrush" candles and vaginal creams in most cases is quite long, averaging about one week. Therefore, the daily use of the drug should be remembered for a long period of time. Despite the long course of treatment, signs of "thrush" in women usually become significantly less visible in the first days of the start of the drug, so many refuse further use. This may cause a recurrent infection.

Preparations of systemic effects

They constitute a means for controlling "thrush" in the form of capsules or tablets, intended for ingestion. They are usually swallowed, drinking plenty of water.

Tablet encapsulated drugs against "thrush" have a systemic effect. They operate from inside the body, creating a high concentration of active substances in many tissues and environments, including urinary tract organs. Due to the action of the system, they eliminate the fungi Candida spp. not only with the vaginal mucosa surface, but throughout its thickness, including microfolds, and with external genital bodies.2.

Furthermore, systemic medications eliminate pathogens "thrush", and other potential habitat of the fungus, for example, in the gut and oral cavity, employees often reservoirs Candida albicans. Thereby minimizing the risk of re-exacerbation of disease after lecheniya3.

With the help of some funds to cure an acute episode of "thrush", you can just once. Undoubtedly, it is very convenient. So modern drug is Flucostat. In most cases, uncomplicated acute forms of "thrush" is enough to receive one capsule 150 mg.

SHOULD partner BE TREATED?

Quite often, after the doctor has confirmed the diagnosis of a woman "thrush", there is a question regarding the need for and feasibility of the treatment of the sexual partner. You should know - "thrush" is not a disease, sexually transmitted. Symptoms "thrush" may occur in a woman, regardless of the presence or absence of sexual activity. But can there be a "thrush" in men? And if so, how to be treated?

Experts do not exclude the possibility that the fungus of the genus Candida can be transmitted to the woman to the man during genital contact. In most cases, getting fungal cells on the penis of the partner does not lead to any consequences for men. Only in a few cases may develop Candida balanitis and / or balanoposthitis. However in women with recurrent "thrush" partner can be a source of regular reinfection.

It is also a certain risk of infection exists for oral-genital and anal-genital contact. In the first case, the source may be a fungal cell of oral mucosa, which is very susceptible to the fungus Candida is often because their natural reservoir. In the second case of the disease are the source of fungal cells from the intestinal mucosa - an ampoule of the rectum. Thus, a woman may pass the fungal infection to a sex partner or be infected by men.

Treatment of men set out in the following cases:

- For partners Women with recurrent "thrush", ie in the presence of 4 or more episodes of exacerbations during the calendar year
- In the presence of clinical symptoms of the disease (cheesy plaque on the glans penis, itching, burning).

How to treat pregnant women with "thrush"?
Pregnancy - one of the common causes that provoke the development of yeast infections in women. Moms, treatment of vaginal candidiasis usually shows outer dosage forms (ointments, gels, suppositories).

Thrush in pregnancy is dangerous for the health of not only women, but also the future baby. It is therefore important even at the planning stage both spouses conduct a full examination. If necessary, even before conception, pre-cure all diseases, including "thrush" which can affect the course of pregnancy, the formation of the fetus and the future health of your baby. This important control of cure by repeated tests. Flucostat - a tool that is suitable for both men and women. In most cases, to eliminate the symptoms of "thrush" enough reception 1-2 Flucostat 150 mg capsules.

Flucostat FAQ

Q. My first time there was a thrush, and I took a capsule Flucostat 150 mg. Flucostat help me or not?

A. Take Flucostat follows the established physician diagnosis of vulvovaginal candidiasis.
Currently, the following regimens are recommended for the treatment of vulvovaginal candidiasis:
1.Odnokratny 150 mg Flucostat. It is recommended for the treatment of uncomplicated forms of the disease with mild to moderate symptoms - usually, this is the first episode of the disease caused or vulvovaginal candidiasis with rare exacerbations (no more than 3 exacerbations per year).
2.Dvukratny reception Flucostat 150 mg with an interval of 72 hours (on the 1st and 4th day). When vulvovaginal candidiasis with severe symptoms (intense itching, burning, swelling of the external genitalia).
3.Shema 3-fold application Flucostat (150 mg 1-4-7 days). It is recommended for recurrent yeast form, which is characterized by frequent repeated exacerbations (4 or more episodes per year). However, in recurrent form of the disease after the disappearance of symptoms of the disease designate another additional maintenance therapy (Flucostat 150 mg 1 time per week for up to 6 months).
The cause of the disease and prescribe appropriate treatment scheme can qualified gynecologist. It is important to know that without the elimination of the predisposing factors of the disease, the treatment of recurrent vulvovaginal candidiasis may be ineffective.

Q. Please tell me Flucostat available on medical prescription?
A. Flucostat drug in pharmacies on prescription. But take Flucostat should be confirmed in the case of the doctor indications for administration of the drug specified in the instructions for use.

Q. Hello, please tell me whether you can take Flucostat during menstruation?
A. The advantage of receiving the drug inside Flucostat is the absence of inconvenience and discomfort, which is usually accompanied by vaginal treatment (Topical) means. Flucostat treatment can begin as soon as there were unpleasant symptoms "thrush", without waiting for the end of menstruation. Take it possible at any time - day or night, regardless of the meal - on an empty stomach or after a meal.

Q. Does Flucostat impact on liver function?
A. According to the instructions for medical use of the drug Flucostat, abnormal liver function (jaundice, hepatitis) refers to a rare side effect of the digestive system. To verify possible contraindications for receiving medication Flucostat you must consult your doctor.

Q. Please tell me, if a man candida balanitis whether to accept or Flucostat it only for women?
A. Indications for Flucostat a man, in case of urogenital candidiasis ( "thrush") he or his partner are:
- The presence of a man signs of Candida balanitis, manifested by white plaque and redness on the penis.
- The presence of his sexual partner recurrent form of vulvovaginal candidiasis ( "thrush" the vagina and external genitalia with a frequency of exacerbation of the mucous membrane - 4 or more times per year).
In the cases listed above administered single dose of 150 mg Flucostat.
Take the drug Flucostat should be confirmed in the case of a doctor diagnosis of urogenital candidiasis.

Q. You can drink alcohol during treatment Flucostat?
A. The effects of alcohol on the efficacy and safety of Flucostat not been assessed, in order to avoid adverse effects on the liver function of alcohol is not recommended during the entire treatment period Flucostat and for 3 days after the last dose Flucostat.

Q. The doctor has diagnosed "thrush" and appointed a vaginal suppositories. Can I replace the candle on Flucostat?
A. For the treatment of thrush (vulvovaginal candidiasis) is used antifungal drugs for systemic and local (candles, intravaginal tablets, creams) therapy. Candles and other dosage forms for intravaginal administration containing antifungal agents are widely used in the treatment of vulvovaginal candidiasis. However, this treatment has several drawbacks. Candles are unevenly distributed throughout the vaginal mucosa and do not eliminate the causative agent from the external genitalia. Also candles and creams have a therapeutic effect only on the surface of the vaginal mucosa, do not affect the mushrooms, located in the deeper layers, and, moreover, have no effect on fungi, localized in the intestine. Thus, after the topical treatment of vulvovaginal candidiasis can be stored reservoirs of infection. The need for long-term treatment (7-10 days), and the inconvenience of using drugs for the topical treatment often causes patients to interrupt treatment. All this increases the risk of recurrence of the disease in their use. In contrast to the local media - reception system Flucostat deprived of all these shortcomings.
The drug is a modern Flucostat antifungal drug for systemic use. Flucostat has high activity against fungi of the genus Candida - Candida pathogens vulvaginita. Within 2 hours after receiving a single 150 mg Flucostat capable of producing high concentrations in the tissues of the vagina, sufficient to eliminate fungi. Thus Flucostat retains its activity for at least 72 hours after administration and is effective not only in the mucosa of the vagina, but also eliminates the fungi of the intestine and the oral cavity.
For the selection of optimal regimens recommend that you re-apply to the doctor. Take the drug Flucostat should be confirmed in the case of a doctor diagnosis of vulvovaginal candidiasis.

Q. You can take during pregnancy Flucostat?
A. Use of the drug in pregnant Flucostat not recommended, except in severe or life-threatening fungal infections, or if the intended effect of the drug is greater than the potential risk to the fetus. When vulvovaginal candidiasis ("thrush") in pregnant women is usually prescribed antifungals local action (for example, vaginal suppositories). We recommend you consult a gynecologist.

Q. Flucostat and fluconazole - one and the same?
A. And Flucostat and Fluconazole is a drug which is an active ingredient fluconazole. The differences between the drugs may be caused by the quality of the substance from which they are made; the list of ingredients and the quality of support that affect the stability and duration of activity of the main active ingredient; quality control level set on the enterprise-manufacturer; Having our own clinical studies have proven the effectiveness of the drug and other factors.

Flucostat is the first drug on the basis of fluconazole domestic production, appeared in the Russian pharmaceutical market. "Pharmstandard" is responsible for the quality and effectiveness of the drug Flucostat. At its production uses only quality European substance. In addition, Flucostat production is carried out in strict accordance with the European GMP quality standard (certified šZV / LV / 2009 / 001H). The presence of the production line of the European GMP certificate testifies to its standards in accordance with the globally recognized quality standard. "Pharmstandard" The company is currently the only Russian company registered in the European database. Flucostat Efficiency confirmed by clinical studies conducted in various leading scientific institutions of the country.

Q. Hello, whether combined oral contraceptives be the cause of "thrush infection"?
A. Indeed, the use of oral contraceptives increases the risk of acute and vulvovaginal candidiasis ( "thrush"). This is due to the fact that the hormones contained in these preparations contribute to the accumulation of glycogen in the cells of the vaginal mucosa. Glycogen, in turn, is a rich nutrient substrate for mushrooms of the genus Candida, agents of vulvovaginal candidiasis.
If you have recurrent form of vulvovaginal candidiasis (4 or more exacerbations per year) and the simultaneous administration of oral contraceptives measures reduce the frequency of recurrence of the disease may include:
1. The use of modern oral hormonal contraceptives with a low content of sex hormones;
2. The use of effective treatments and prevention of recurrence of vulvovaginal candidiasis. When recurrent vulvovaginal candidiasis form (the frequency of exacerbations of the disease, and more than 4 per year) for the treatment of acute drug prescribed reception Flucostat 150 mg 1 time per day with an interval of 72 hours (1, 4 and 7 night)
However, in recurrent form of the disease after the disappearance of symptoms of the disease designate another long course of preventive therapy (Flucostat 150 mg 1 time per week for up to 6 months), which allows to prevent acute vulvovaginal candidiasis with high efficiency.
In the case of the onset of symptoms of vulvovaginal candidiasis in patients receiving oral contraceptives should consult your obstetrician-gynecologist for the selection of the drug with less estrogen component.
Take the drug Flucostat should be confirmed in the case of a doctor diagnosis of vulvovaginal candidiasis.

Q. Tell me, please, when it is the effect of the action Flucostat?
A. Efficiency Flucostat in the treatment of vulvovaginal candidiasis ( "thrush"), including the time of appearance of clinical effect, largely depend on the severity of the disease, the individual characteristics of the patient, the sensitivity of the infectious agent to the drug (resistance of Candida fungi to Flucostat quite rare) . On average, the reduction of symptoms of vulvovaginal candidiasis ( "thrush") can be expected within 2 days after receiving Flucostat drug.
Take Flucostat should be confirmed with a physician diagnosis of vulvovaginal candidiasis. In other inflammatory diseases of the vagina the drug may be ineffective.
In the case of clinical efficacy (eliminate the symptoms of thrush) renting repeated analyzes is not mandatory.

Q. When "thrush" can have sex? Whether it is dangerous for me and my partner?
A. Having sex is not forbidden, but not recommended for "thrush". This is due to the fact that during intercourse to vaginal mucosa appear microcracks that may lead to increased symptoms or exacerbation of vulvovaginal candidiasis. Despite the fact that "thrush" is not a disease, sexually transmitted diseases, however, there is a slight risk of infection during sexual intercourse. Therefore, if you decide to be sexually active during the treatment of vulvovaginal candidiasis, it is necessary to minimize the trauma of vaginal mucosa (including the use of lubricants) as well as the use of condoms. Also, if you have recurrent form of vulvovaginal candidiasis (the frequency of exacerbations and more than 4 times a year), the treatment should receive, and your sexual partner. In this form of the disease higher risk of sexual transmission of Candida ( "thrush" agents), and, as a consequence of infection recurrence after the treatment.