Amphetamine: Research, Real Effects

A new story about drugs! By tradition, we will examine the drug most unbiased, outside view, so to speak. As for the issue of cigarettes, pay attention not only on the disadvantages and harm which are all so heard, and shall find possible benefit from its use. If your nerves are beginning to be naughty and angry, because like so: plus amphetamine that ?! So let's say right away that propaganda will not, and will be the facts.

What is amphetamine?

This is one of the most powerful psycho-stimulant that were ever created. Kalashnikov assault rifle in the world of stimulants is extremely effective, and, in unskilled hands is dangerous. The word "psychomotor" means action at the same time on the psyche and on the motility, we can say, the entire nervous system is stimulated.

Originally this substance was produced by well-intentioned: the treatment of chronic alcoholism, obesity, depression treatment.

It used in medicine and currently in various forms such as dextro-amphetamine and Levo-amphetamine example. In the US indicated for ADHD, but they have, in the course of such drugs like Adderall and Dexedrine.

How does amphetamine act?

• 1.It increased dopamine. Recall that dopamine is responsible for the motivation and joy. Numerous studies confirm this effect. Amphetamine causes the body to produce more of a neurotransmitter, it even easier to see the process of passing through the cytoplasm inside the cell, one can say lubricates vesicles, which is transported in the balls dopamine. This matter becomes much, but how much? There are a variety of data, depending on the dose and those on whom experienced.

Since 5 mg / kg in rats increased dopamine concentration at 950%. Dosages of 0.2 mg / kg in rats also causes a slight increase in dopamine. Human studies show a serious increase in dopamine in doses of 0.9 mg / kg in the meso-limbic pathways responsible for pleasure, memory and emotions.

• 2.The increase in norepinephrine. Moreover, in percentage terms, growth of more than norepinephrine dopamine.
• 3.Increasing of Serotonin. Serotonin, in experimental rats was increased 5-fold, at doses of 1 mg / 1 kg. There is also compared antidepressants and other drugs. Amphetamine derivative - MDMA, by the way, to increase the concentration of serotonin in the 12 times, at a dose of only 0.3 mg / kg.
• 4.An inhibitor of the reuptake of monoamines. Amphetamine partially blocks the reuptake of dopamine, serotonin and norepinephrine, in addition to the main output. Ie it is not only the "swings" substances, but also prolongs their life, their use by the body.

Now we focus on the pros and cons. Immediately it is worth saying that many will begin to bomb and will write that the fake research, etc.

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Pros of amphetamine:

+ Briefly improves intellectual abilities, especially - RAM. On this subject there is a lot of research.

One of them is carried out not so long ago, in July 2015. In it there is evidence that lower doses of psychostimulants act solely as cognitive enhancers and have virtually no side effects. In another study compared cocaine, amphetamine, caffeine and modafinil in different dosages. And it is also confirmed psychostimulants cognitive effects at low doses and high frequency of side effects at higher doses.

Therapeutic dosage of amphetamine - 50 mg, for reference.

Important clarification: When taken regularly, these effects are much weaker!

+ Real treat for ADHD in Western countries. ADHD - this unusual disorder in which will be a separate release. The use of stimulants at course intake in these patients improves the functioning of the brain, stimulates the growth of nerve. There is real data that ESP intake amphetamines over 2 years in patients with ADHD does not result in destruction of the brain, but rather on the contrary, while they have no dependencies.

Can you imagine if an ordinary person catches dependence through several stages, the patient with ADHD may take years of amphetamine derivatives with benefits for the body!

+ Improved performance, endurance, decreased reaction time, improve memory. Very handy thing in sports and in extreme situations.

I'll tell you about one study of 31 people, average age - 22 years old, 16 women. They have a low level of alcohol consumption, 10 smokers. We can say, ordinary people. They were divided into 3 groups: placebo, 10 mg of amphetamine, 20 mg of AMP. Self testing was quite interesting and revealing, from which you can make far-reaching conclusions.

The bottom line: people had to memorize words and pictures, which in turn were divided into neutral, positive and negative. The results make us think! What amphetamine improves short-term memory are nothing new, but almost no reaction to the neutral words and pictures.

Think! If we amphetamine could not force a person to remember something he was not interesting, then, most likely, no stimulant can not. And every time you'll strain your head, you should refer to the project with interest, not give a fuck.

Cons and harm of amphetamine

First of all, we recall that the positive effects are possible under normal manufacturing and clinical dosages. Amphetamine is prohibited in almost all countries, this implies the first negative - poor quality of what is sold illegally. As in the famous expression: "fools and roads", the second negative - the consumers, fools, they play with a Kalashnikov assault rifle in the world of drugs, besides collected is not clear how and where.

Now the details:

- Addiction. As has been previously stated, the longer take - the more addiction, tolerance is produced. To achieve previous effects require more substance. And the effects of his bright, it means that in the beginning, develop a psychological dependence, then - physical.

All people have different degrees of tolerance, someone the drug "enslave" in 1-2 reception, someone will last longer.

- General malfunctions of the organism. Because the mechanism of action - amphetamine increases the concentrations of dopamine, norepinephrine and serotonin. He introduces significant changes in the biochemistry of the brain. But if the machine is constantly going at high speed, in the red zone, it is clear where it leads. With amphetamine our brains will not last long, and, above all, break dopaminergic system: mood swings, impaired motor skills, the lack of any motivation and thirst for action.

- Abnormalities in the circulatory system. Here such sores as tachycardia and hypertension. All sorts of terrible pictures "before and after amphetamine" owe much of that paragraph. People often underestimate the cardiovascular diseases, meanwhile, according to statistics, you will die with a probability of 70-80% due to them. Blood performs very important functions including, it delivers nutrients to the cells, cleans and from there all sorts of rubbish. Failure in this system, almost all degrade in the body.

At the end we present a picture of the release of the drug, the comparative characteristic of amphetamine. As such, it is not an amphetamine, cocaine but is analog. And the desire to increase the dosage of strongest among other drugs.

Bottom Line:

- Amphetamine - a very strong stimulant

- Amphetamine works by increasing the production of dopamine, noradrenaline and serotonin. Blocks of reuptake. - Its advantages are: the improvement of short-term memory, increased mobility, stimulation.

Cons: disturbances in the functioning of neurotransmitters, in violation of circulation, the desire to increase the dosage and dependence.

Assuming Amphetamine is not advised, it is illegal, and therefore its quality no one was watching, which means even more side effects.

And if you think about it, there are many legal stimulants, which have much smaller minuses.