DMAE or dimethylaminoethanol

DMAE or dimethylaminoethanol in the last few years is gaining rapid popularity in the CIS countries. This addition refers to the group of nootropics that conventionally "safe" and, as a consequence, taken all in a row to achieve a variety of purposes: anti-aging, to improve the metabolic processes in the brain to improve athletic performance. Because the spectrum of the "target audience" this additive is very wide. And thanks to globalization and marketing, it can be assumed that the target audience of this additive does not become less.

What is DMAE

DMAE is a natural nootrop, dietary supplement, found in foods such as salmon and sardines.

Chemical structure of DMAE and choline (vitamin B4) differ slightly. Choline bromide has additional molecule which is attached to the nitrogen molecule. Hence we can say that choline and DMAE - are relatives. A choline, as we know, there are a precursor of acetylcholine, from which then creates the main neurotransmitter responsible for the training.

By the way here's another paradox in the European Union DMAE is sold as Deanol - prescription medicine. In Russia DMAE sells as a dietary supplement.

How does DMAE act?

In the process of digestion, DMAE acts in two ways:

• A.DMAE liver under the influence of methionine becomes choline, which already acts on acetylcholine. Ie it turns out the indirect action.
• B.In the intestine, this additive is directly absorbed into the blood and into the brain, the same acting on acetylcholine. The second embodiment indicates that DMAE faster this enhances neurotransmitter than choline suction from the liver. But this method is considered ineffective. Since this additive, when absorbed from the intestine, little effect on acetylcholine.

After entering the blood DMAE following occurs:

• 1.It passes the blood-brain barrier, enters the brain.
• 2.Raising choline occurs through inhibition of its transport from the bloodstream. When blood choline much - much in its central nervous system, as a result, becomes much and acetylcholine. If we "do not allow the body to flush out the kidneys, liver, intestines," choline from the blood, we increase its efficiency in the brain. But there is also evidence that inhibition of excessive, can harm the unborn child.
• 3.DMAE under the influence of the enzyme betaine homocysteine methyltransferase (BHMT) partially becomes dimethylglycine (DMG), which is used as a stimulant in sport and trimethylglycine (TMG) or betaine, which serves mainly as a hepatoprotective.
• 4.DMAE inhibits / prevents transport and metabolism of choline to phosphocholine and phosphatidylcholine. Phosphatidylcholine is used to generate membranes in CNS cells. This is a very important process, inhibited for a long period of time can cause aging and death of nerve cells. This is unnecessary dilution of the cement with water or sand. Under the terms of the long period of the year refers to regular admission. However, with sufficient Phosphatidylcholine use of conventional food: eggs, nuts, fish, and the negative effect of DMAE is reduced to zero.

Summarized as: DMAE enters the bloodstream through the intestines and the liver. Further, partly produces choline and acetylcholine, partly Dimethylglycine and Trimethylglycine.

Course of DMAE

As already mentioned above, at regular, very long reception, no specific figures can be observed apotoz, the destruction of nerve cells.

It is also not desirable intake for pregnant women because of the inhibition of choline transport (but this study was conducted with mouse embryos). Generally, you can not use unclear terms in a negative context, otherwise people magnified. DMAE - a natural supplement that is part of the fish! But that, in theory, could lead to bad consequences for chronic use. The same can be said about sugar, for example.

Side effects: Hypersensitivity, excitement, insomnia.

The course of DMAE 2 months at 700-1000 mg / day. Divide into 2-3 doses, the last hours of 4-5 to sleep, and then suddenly it will stimulate you) Because DMAE is contained in the food, it would be logical to take it with food, on the other hand, strict framework is not here.

Effects:

• 1.Life Extension. This effect is most know, the experiment was carried out in 1973 on his arm, and they lived longer than their counterparts by 30-50%.
• 2.DMAE improves and synchronizes to a large extent, the transmission of signals between the brain hemispheres on the results of the EEG (the study of the 86th year) This means better brain integrity is not only memory and learning, but also other brain functions. You will not be super-brain, but the brain is like a computer or a fresh website with properly-written code.
• 3.Improves learning. The experiment on children, banal, one giving a pacifier, others DMAE, nobody knew who that, after 3 months the group with DMAE showed the best progress in achievement, the figures are not crazy, but also not an accident. You can also improve learning with Phenylpiracetam, Adrafinil, Phenotropil, Vinpocetine.
• 4.Fatigue, depression decreases. There were 2 similar studies, one of 52 people in the other 100, both groups improved their health.
• 5.Antioxidant effect. Cleaning free radicals. However, it is insignificant.
• 6.Presumably, the increased levels of dopamine. Creates Dimethylglycine and Trimethylglycine. This bundle has the effect of light stimulation and concentration.

To help DMAE

DMAE works fine with a good source of choline, such as lecithin, Choline Alphoscerate or just eat a lot of eggs, nuts and seafood.

Interestingly looks bunch of l-tyrosine (dopamine) and 5 HTP is (serotonin).

Bottom line:

• DMAE - this is a useful supplement for brain health.
• DMAE runs through several channels: acetylcholine, choline, dimethylglycine, dopamine.
• Effects: mild stimulation, improved brain functioning, the struggle with depression.
• Course and Dosage of DMAE: 2 months, 700-1000 mg / day, 2-3 hours, the last 4-5 hours before bedtime.
• Desirable add choline, lecithin, or simply eat well.