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Dimephosphon (Dimethyloxobuthylphosphonilmethylate) - antiatsidoticheskie displays, membrane, anti-inflammatory and antioxidant properties, normalizes blood flow and metabolism of the brain tissue, reduces cardiac and pulmonary failure, improves the regulation of blood circulation, including cerebral.
Antiatsidoticheskoe action is realized due to the intensification of renal and pulmonary mechanisms regulating acid-base balance, enhance intraorganic blood flow and tissue metabolism, Dimephosphon also reduces the content of lactic and pyruvic acids in brain tissue.
Dimephosphon stabilizes cell membranes, restoring the responsiveness of cerebral vessels, improving the function of the cerebral hemispheres and brain stem, reduces the depth of impaired consciousness and restores the sleep-wake cycle, the reflexes, the arc of which are closed by stem sections, reduces the severity of pyramidal, cerebellar, vestibular, visual and hearing disorders.
Antioxidant action is carried out by preventing the activation of lipid peroxidation and increase the activity of antioxidant enzymes in the brain tissue.
Dimephosphon enhances energy processes in the brain either directly acting directly on the mitochondria, and indirectly, by stimulating the pituitary-thyroid system, increasing consumption of tissues of the thyroid hormones, which is accompanied by the activation energy and catabolic processes in the mitochondria of cells. Shows properties of certain neurotransmitters (GABA-positive, H-choline and dopaminergic activity).
Dimefosfon reduces cardiac and pulmonary failure, restoring the resistivity of peripheral vascular (arterial and venous).
Dimephosphon improves the regulation of the cerebral circulation, without having pronounced vasodilating effect, but a positive effect on the metabolism of the brain tissue when ischemia, improves venous outflow. Clinical Efficacy of drugs in various forms of cerebrovascular disease is related to its ability to increase the resistance of nerve cells to ischaemia with a decrease in swelling and, therefore, improvement of microcirculation.
When applied topically Dimephosphon has anti-inflammatory and antiseptic effect, increases the protective function of the skin and mucous membranes.
It normalizes the acid-base status at different etiology Acidosis. Shows membrane stabilizing, anti-inflammatory, immunomodulatory, Antihypoxanth, antimutagenic and radioprotective action inhibits platelet aggregation.
When applied topically, has an antiseptic effect, increases the protective function of the skin and mucous membranes.
Pregnancy and breast-feeding:
Currently, the use of these drugs in pregnancy is insufficient to assess the teratogenic DimefosfonaŽ.S DimefosfonŽ this regard should be used during pregnancy and lactation only if the anticipated benefits of its use outweighs the potential risk to the fetus or breast child.
Animal studies have not revealed the damaging effect on the embryo and its development.
Inside appointed as a solution for adults and children 30 - 50 mg / kg at the reception. When violations of cerebral circulation, and Meniere's syndrome administered 1-4 times during 1-4 weeks.
When the planned neurosurgical operations prescribed for 5 days before and 10-14 days after the operation. With traumatic brain injury treatment duration from 3 weeks to 2 months.
When autonomic dysfunction, diseases of the respiratory acidosis and duration of treatment 3-4 weeks. In atopic asthma in children prescribed for 2-4 weeks.
For the prevention of acute hay fever be taken within 3 weeks before the expected seasonal deterioration and throughout the flowering plant allergen.
External used in infectious and inflammatory and allergic diseases of the skin and the mucous membranes of the solution in the form of dressings, and lotions turundas daily until recovery.
For the prevention of radiation mucositis - gauze moistened with a solution to fit the projection beams of radiation for 20 minutes before exposure dose.
Important notice- the outer box design may vary before prior notice!
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Mexidol injection 5 vials, 5ml per ampul