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Anvifen (Acidum aminophenylbutyricum, Aminophenylbutyric acid) - nootropic agent facilitates GABA-mediated transmission of nerve impulses in the central nervous system (direct effect on GABA receptors). Tranquilizing effect combined with an activating effect. It also has antiplatelet, antioxidant and some anticonvulsant effects.
It improves the functional state of the brain due to the normalization of metabolism and its effect on cerebral blood flow (increased volumetric and linear speed, reduces vascular resistance, improves microcirculation, has antiplatelet effect). It extends the latent period and shortens the duration and severity of nystagmus.
No effect on choline and adrenergic receptors. Reduces vasovegetative symptoms (including headache, a feeling of heaviness in the head, sleep disturbances, irritability, emotional lability). In exchange reception improves physical and mental performance (attention, memory, speed and accuracy of sensory-motor reactions).
It reduces the symptoms of fatigue (improves mood, increases the interest and initiative - motivation activities) without sedation or excitation.
Reduces feelings of anxiety, tension and anxiety, normalizes sleep.
In the elderly does not cause CNS depression, muscle-relaxing-effect often absent.
Hypersensitivity, pregnancy, breastfeeding, children under 3 years.
Precautions: during erozivnoyazvennom lesions of the gastrointestinal tract, liver failure.
With prolonged use is necessary to periodically monitor the performance of the liver and peripheral blood functions. Effects on ability to drive and use machines. It should refrain from potentially hazardous activities that require high concentration.
It extends and enhances the effect of hypnotics, narcotic analgesics, antipsychotics, antiparkinsonian and antiepileptic agents.
Inside, after eating, 2-3-week course.
Adults and children from 14 years - 250-500 mg 3 times daily (maximum daily dose - 2500 mg). Children 3-8 years - 50-100 mg three times a day; 8 - 14 - 250 mg 3 times a day.
The single maximum dose in adults and children 14 years of age is 750 mg in patients over 60 years - 500 mg, for children up to 8 years - 150 mg, from 8 to 14 years - 250 mg.
Alcohol withdrawal syndrome: 250-500 mg 3 times a day and 750 mg at night, with a gradual decrease in the daily dose to adult normal.
Treatment of vertigo with vestibular dysfunction and Meniere's disease: 250 mg 3 times a day for 14 days.
Prevention of motion sickness: 250-500 mg once daily, for 1 hour before starting pitching, or when the first symptoms of seasickness.
Antiseasick Anvifen action of the drug increases with increasing dose. When the express manifestation of motion sickness (vomiting, etc.), use of the drug is ineffective Anvifen even at doses of 750-1000 mg.
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