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DR. DOPING

Instructions

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Instruction for use: Psorcutan

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Active substance Calcipotriol

ATX code D05AX02 Calcipotriol

Pharmacological group

dermotropic means

Nosological classification (ICD-10)

L40 Psoriasis

Chronic psoriasis with diffuse plaques, Generalized psoriasis, Psoriasis of the scalp, Psoriasis of the scalp, Generalized form of psoriasis, Psoriasis dermatitis, Psoriasis complicated by erythroderma, Invalidative psoriasis, Isolated psoriatic plaque, Exfoliative psoriasis, Psoriatic Erythroderma, Psoriasis with eczematosis, Hyperkeratosis in psoriasis,Inverse psoriasis,Psoriasis eczematous, Dermatosis of psoriasis, Psoriasis of the genitals, Psoriasis with lesions of hairy areas of skin, Erythrodermal psoriasis, Chronic psoriasis of the scalp, Chronic psoriasis, Ordinary psoriasis, Refractory psoriasis, Kebner phenomenon, Scaly lichen

Composition and form of release

1 g of ointment or cream contains calcipotriol 50 μg; in tubes of 30 grams, in a box of 1 tuba.

1 ml of solution for external use - 50 mg; in bottles of 30 and 60 ml, in the box 1 bottle.

pharmachologic effect

The pharmacological action is antipsoriatic.

Normalizes the proliferation and differentiation of keratinocytes.

Pharmacokinetics

When topical skin application absorbs no more than 1% calcipotriol. Part of the absorbed quantity undergoes rapid biotransformation in the liver with the formation of low-activity metabolites. The resorbed drug is excreted by the kidneys and intestines

Indication

Psoriasis.

Contraindications

Hypersensitivity, a progressive stage of psoriasis, pustular psoriasis, diseases accompanied by impaired calcium metabolism, severe kidney and liver damage.

pregnancy and lactation

Not recommended during pregnancy. Breastfeeding mothers should stop breastfeeding during treatment.

Side effects

In rare cases: skin irritation (itching, burning or redness); can be marked dermatitis (face, perioral region).

Dosing and Administration

Ointment, cream: applied to the affected skin 1-2 times a day. The maximum daily dose is 15 g (not more than 100 g per week). The course should not exceed 1 year.

Solution: Apply 2 times a day to the affected areas of the scalp and lightly rub (no more than 60 ml per week). When used simultaneously with cream or ointment, the total dose of calcipotriol should not exceed 5 mg per week (ie 60 ml of solution and 30 g of cream or ointment, or 30 ml of solution and 60 g of cream or ointment). The duration of treatment depends on the clinical picture.

Overdose

Symptoms: the development of hypercalcemia.

Treatment: it is necessary to interrupt treatment and weekly monitor the serum calcium level.

Precautionary measures

It is not recommended to use simultaneously with salicylic acid and preparations containing it. Appointment to patients younger than 18 years is possible only in short courses, and in the event that other drugs do not bring a satisfactory result. It is necessary to avoid getting the solution on mucous or healthy skin areas. Do not apply to the skin except for the border of hair growth.

special instructions

Treatment with Psorcutan can be combined with photochemotherapy (PUVA) and selective phototherapy (SFT).

storage conditions

At temperatures below 25 ° C.

Keep out of the reach of children.

Shelf life

2 years.

Do not use after the expiry date printed on the package.

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