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Instruction for use: Prozac

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Dosage form: capsules

Active substance: Fluoxetine*


N06AB03 Fluoxetin

Pharmacological groups:


The nosological classification (ICD-10)

F32 Depressive episode: Adynamic subdepression; Astheno-adynamic subdepressive states; Asthenoadressive disorder; Astheno-depressive disorder; Asthenodepressive state; Astheno-depressive state; Major Depressive Disorder; Vyaloapatichesky depression with retardation; Double Depression; Depressive pseudodement; Depressive illness; Depressive mood disorder; Depressive disorder; Depressive mood disorder; Depressive state; Depressive disorders; Depressive syndrome; Depressive syndrome larviated; Depressive syndrome in psychoses; Depressed masks; Depression; Depression Depletion; Depression with the phenomena of inhibition within the framework of cyclothymia; Depression is smiling; Involutional depression; Involutionary melancholy; Involutional depression; Manic-depressive disorder; Masked Depression; Melancholic Attack; Neurotic depression; Neurotic depression; Shallow Depression; Organic depression; Organic depressive syndrome; Simple depression; Simple melancholic syndrome; Psychogenic depression; Reactive depression; Reactive depression with moderate psychopathological symptoms; Reactive depressive states; Reactive depression; Recurrent depression; Seasonal depressive syndrome; Severostatic depression; Senile Depression; Symptomatic Depression; Somatogenic depression; Cyclotymic depression; Exogenous depression; Endogenous depression; Endogenous Depressive Conditions; Endogenous Depression; Endogenous depressive syndrome

F42 Obsessive-compulsive disorder: Obsessive-compulsive syndrome; Obsessive compulsive states; Obsessive-compulsive syndrome; The Obsession Syndrome; The obsession neurosis; Obsessive-compulsive neurosis; Obsessions

F50.2 Nervous Bulimia: Bulimic Neurosis; Bulimia; Wolf hunger; Kinorexia

Composition and release form

1 capsule contains fluoxetine 20 mg (in the form of hydrochloride); in a cardboard box 1 blister for 14 pcs.

1 soluble tablet - 20 mg; in a cardboard box 2 blisters for 14 pcs.

Pharmachologic effect

Pharmacological action - antidepressant.

Blocking the reverse capture of serotonin by neurons of the brain.

Indications for the Prozac

Depression, bulimia nervosa, obsessive-compulsive disorder (obsessive thoughts and actions).



Application in pregnancy and lactation

Not recommended for pregnancy and lactation.

Side effects

At the beginning of therapy and with increasing doses, anxiety and irritability, sleep disturbances, drowsiness, headache, nausea may appear; less often - vomiting and diarrhea. Perhaps the development of anorexia and a decrease in body weight, as well as the appearance of hyponatremia, especially in elderly patients. Rarely, the onset of convulsive seizures. Possible allergic reactions in the form of skin rash, itching, chills, fever, pain in the muscles, joints.


Incompatible with MAO inhibitors (from the moment of stopping the intake of MAO inhibitors before the start of therapy should be at least 14 days, after the abolition of fluoxetine, a new method of MAO inhibitors is allowed, at least, after 5 weeks). Changes the level of lithium in the blood. In combination with tryptophan and phenytoin, the risk of side effects increases.

Dosing and Administration

Inside, with depression, the initial dose is 20 mg / day. Increase in the dose (in the absence of clinical effect) is possible in a few weeks, after consulting a doctor. Doses over 20 mg / day are taken in 2 divided doses. Patients with severe impairment of liver or kidney function are recommended to reduce the daily dose. With bulimia nervosa - daily dose of 60 mg (in 3 divided doses). The maximum daily dose should not exceed 80 mg. In obsessive-compulsive disorders, 20-60 mg / day.

Storage conditions for Prozac

In the dark place at a temperature of 15-30 ° C.

Keep out of the reach of children.

Shelf life of Prozac

tablets are soluble 20 mg - 2 years.

capsules 20 mg - 3 years.

Do not use after the expiry date printed on the package.

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