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Instruction for use: Propazine solution 2,5% in ampules

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Dosage form: solution for injection for 2.5%

Active substance: Promazine*


N05AA03 Promazine

Pharmacological group:


The nosological classification (ICD-10)

E80 Disorders of porphyrin and bilirubin metabolism: Urokoppororphyria; Late skin porphyria; Functional hyperbilirubinemia; Disturbances of pigmental metabolism; Porphyrin disease; Erythropoietic protoporphyria; Erythropoietic uroporporphia; Symptomatic porphyria

F20 Schizophrenia: Schizophrenic conditions; Exacerbation of schizophrenia; Schizophrenia; Chronic schizophrenia; Dementia praecox; Bleuler's disease; Psychotic discordant; Dementia early; The febrile form of schizophrenia; Chronic schizophrenic disorder; Psychosis of the schizophrenic type; Acute form of schizophrenia; Acute schizophrenic disorder; Cerebral Organic Insufficiency in Schizophrenia; Acute attack of schizophrenia; Schizophrenic psychosis; Acute schizophrenia; Sluggish schizophrenia; Sluggish schizophrenia with apathoabulic disorders; Acute stage of schizophrenia with excitation

F28 Other Inorganic Psychotic Disorders: Affective psychoses; Involutional psychosis; Psychoinstrumental; Psychic senile; Senile psychosis; Structural Involutionary Psychosis; Static psychosis

R11 Nausea and vomiting: Postoperative vomiting; Nausea; Vomiting; Vomiting in the postoperative period; Vomiting medication; Vomiting in the background of radiation therapy; Vomiting uncontrollable; Vomiting in radiation therapy; Persistent vomiting; Indomitable vomiting; Postoperative nausea; Vomiting with chemotherapy; Vomiting of the central genesis; Vomiting with cytotoxic chemotherapy; Persistent hiccups; Repeated vomiting

R50 Fever of unknown origin: Malignant hyperthermia; Hyperthermia malignant

Composition and release form

1 ml of solution for injection contains promazine 25 mg; in the package 5 ampoules of 2 ml.

Pharmachologic effect

Pharmacological action - antihypertensive, antihistamine, neuroleptic, antiemetic, sedative.

Indications Propozine solution 2.5% in ampules

Psychoses, schizophrenia, vomiting with chemo- and radiation therapy, malignant hyperthermia, porphyria.


Alcoholism, shock and coma, organic lesions of the central nervous system, epilepsy, Parkinson's disease, respiratory disorders, breast cancer, liver and kidney disease, prostate adenoma, blood diseases, glaucoma.

Application in pregnancy and lactation


Side effects

Hypotension (up to the collapse), extrapyramidal disorders, dyspeptic disorders, hepatitis, allergic reactions.


Strengthens the effect of alcohol, tranquilizers, analgesics, sleeping pills and narcotic drugs; reduces the effectiveness of bromocriptine and antiparkinsonian drugs.

Dosing and Administration

Adults IM - 10-100 mg every 6-12 hours. The highest daily dose is 2 g. Children older than 12 years - 10-25 mg every 6-12 hours. The highest daily dose is 1 g.

Precautionary measures

Use with caution in children under 12 years.

Conditions for storage of Propazine solution 2,5% in ampules

In the dark place.

Keep out of the reach of children.

Shelf life of the drug Propazine solution 2,5% in ampules

1 years.

Do not use after the expiry date printed on the package.

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