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Instruction for use: Optalgin

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Active substance Metamizole sodium

ATX Code N02BB02 Metamizole sodium

Pharmacological group

NSAIDs - Pyrazolones

Nosological classification (ICD-10)

K13.7 Other and unspecified lesions of oral mucosa

Aspirin burn of the oral mucosa, Gum pain when wearing dentures, Inflammation of the mouth, Inflammation of the oral mucosa, Inflammation of the oral mucosa after radiation therapy, Inflammation of the oral mucosa after chemotherapy, Inflammation of the oral mucosa, Inflammation of the mucous membranes of the mouth, Inflammatory diseases of the oral cavity, Inflammatory process of pharynx, Disease of the oral mucosa, Injuries to the oral cavity and larynx, Injuries of the oral mucosa, Trophic diseases of the oral mucosa, Erosive-ulcerative periodontal disease, Erosive-ulcerative lesion of the oral mucosa, Erotic mucous membrane of the oral cavity, Erotic-ulcerative periodontal lesions, Erotic-ulcerative lesions of the oral mucosa, Radio-epileleitis, Irritation from dental prostheses, Irritation of the oral mucosa with dentures and braces, Oral cavity, When wearing dentures

N94.6 Dysmenorrhea Unspecified

Pain during menstruation, Functional disorders of the menstrual cycle, Menstrual cramps, Emmeniopathy, Pain during menstruation, Painful menstrual irregularities, algomenorrhea, algomenoreya, Pain smooth muscle spasm, Pain spasm of smooth muscles (renal and biliary colic, intestinal spasms, dysmenorrhea), Pain spasm of smooth muscles of internal organs (kidney and biliary colic, intestinal spasms, dysmenorrhea), Disalgomenoreya, dysmenorrhea, Dysmenorrhea (essential) (Exfoliative), menstrual disorder, menstruation painful, metrorrhagia, Violation of the menstrual cycle, Menstrual irregularities, Prolaktinzavisimoe menstrual disorders, Prolaktinzavisimoe menstrual dysfunction, Pain spasm of smooth muscles of internal organs, Spasmodic dysmenorrhea, Primary disalgomenoreya

R50 Fever of unknown origin

Malignant hyperthermia, Hyperthermia malignant

R51 Headache

Pain in the head, Cephalgia, Pain with sinusitis, Pain in the back of the head, Painful headache, Headache of vasomotor genesis, Headache of vasomotor origin, Headache with vasomotor disorders, Headache, Neurological headache, Serial headache

R52.2 Other constant pain

Pain syndrome, rheumatic origin, Pain at vertebral lesions, Pain in the chamber, Pain for burns, Pain syndrome weak or moderate, Perioperative pain,Moderate to severe pain, Moderately or weakly expressed pain syndrome, Moderate to severe pain, Ear pain of otitis, Neuropathic pain, neuropathic pain

Composition and form of release

1 tablet, 1 ml solution for oral administration (25 drops) or 1 ml solution for injection contain metamizole sodium 500 mg, in a package of 10 pcs., In bottles of 10 ml or in ampoules of 2 ml, in a package of 5 pcs. respectively.


Moderate and severe pain (headache, dental, with dysmenorrhea), fever.


Hypersensitivity to pyrazolone derivatives in anamnesis, age (up to 3 months).

pregnancy and lactation

Safety of use in pregnancy is not established.

Side effects

Disorders of the gastrointestinal tract (nausea, vomiting, etc.), agranulocytosis, rashes on the skin, anaphylactic shock.


Strengthens chlorpromazine hypothermia.

Dosing and Administration

Inside for 1-2 tablets or 25-50 drops of the solution no more than 4 times a day. Children 3-5 months - 3-5 drops, 6-24 months - 5-10 drops, 3-7 years - 10-20 drops, 8-11 years - 15-30 drops, 12-14 years - 20-40 drops not more than 4 times a day. Children younger than 3 months of the appointment of the drug inside is not recommended. If necessary, in this appointment should be applied to 1 drop 3 times a day. In severe pain syndrome injected in / m deep in a single dose of 2-5 ml per day; multiplicity of administration up to 3 times a day. If necessary, it can be injected intravenously slowly in a single dose of 0.5-2 ml; the frequency of administration is up to 3 times a day. Maximal doses: single dose - 1 g, daily - 3 g.

Precautionary measures

Be wary appoint in pregnancy, patients with an increased risk of developing hypersensitivity reactions, such as patients with bronchial asthma, chronic urticaria, as well as in the presence of anamnestic information about intolerance of other analgesics and antirheumatic drugs. Patients with high fever require careful observation.

Storage conditions

Keep out of the reach of children.

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