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Instructions

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Instruction for use: Nefluan

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Active substance Neomycin + Fluocinolone acetonide + Lidocaine

ATX code G04BX Preparations for the treatment of urological diseases others

Pharmacological group

Glucocorticosteroids in combinations

Nosological classification (ICD-10)

I84 Hemorrhoids

Painful hemorrhoids, External hemorrhoids, Internal hemorrhoids, Inflammation of hemorrhoids, Aggravation of hemorrhoids, Chronic bleeding hemorrhoids, Acute hemorrhoidal attack

K60 Fissure and fistula of anus and rectum

Anal fissure, Acute anal fissure, paraproctitis chronic, perianal crack, Surface anal fissure, Fistulas of the rectum, Crack rectum, Cracks anal area, Cracks anus, Cracks rectum, Chronic anal fissures, Chronic periproktit, Sentry bump

K62.8.1 * Proctitis

Atrophic proctitis, Anusitis

K94 * Diagnosis of gastrointestinal diseases

Liver-spleen scan is, The visualization of the liver using invasive methods, Isotope hepatoscintigram, Celiocentesis, examination of the liver, Magnetic resonance imaging of the liver, Computed tomography of the liver, Esophageal manometry, Anoscopy, Visualization of biliary tract, liver ultrasound visualization, Gastroscopy,degassing bowel before diagnostic studies, degassing intestine before X-rays, Diagnosis of the gastrointestinal tract, Diagnosis of bleeding from the small intestine, Diagnosis of focal lesions of the liver, Diagnosis secretory capacity and gastric acid-function, Diagnostic procedures on the colon, duodenal intubation, duodenoscopy, Instrumental examinations of the abdominal cavity, Intraoperative cholangiography, Irrigoscopy, The study of gastric secretion, GI study, Investigation of acid-forming function of the stomach, The study of gastric secretory function,Colonoscopy, Monitoring the effectiveness of lithotripsy, Determining the degree of hypersecretion of duodenal ulcer, Preparation for diagnostic tests, Preparing to X-ray and instrumental methods of investigation of the abdominal cavity, Preparing to X-ray and ultrasound of the abdominal cavity, Preparing to X-ray or endoscopic gastrointestinal investigations, Preparing to X-ray study of the gastrointestinal tract with contrast, Preparing to X-ray study of the gastrointestinal tract with barium, Preparing to X-ray examination and ultrasound of the abdomen, Preparing to X-ray examination and ultrasound of the abdomen, Preparation for ultrasound and X-ray examination of the abdominal cavity, Preparation for endoscopic examination of the lower large intestine,Preparation for endoscopic or X-ray examination of the lower intestine, Prepare to lower GI endoscopy, Preparation of the colon to the instrumental and radiological investigations, Preparation of the colon to the x-ray and endoscopy, sigmoidoscopy, rectoscopy, GI Radiography, X-ray diagnosis of esophageal achalasia,Radiology gastrointestinal diseases, Radiology of the digestive tract, Rentgenocontrast study biliary tract, Rentgenocontrast study GI, X-ray diagnosis of the gastrointestinal tract, X-ray gastrointestinal studies, X-ray examination of the duodenum and gall bladder, X-ray examination of the stomach, X-ray examination of the biliary tract and gall bladder, X-ray study of the gastrointestinal tract, X-ray examination of the esophagus, retrograde cholangiopancreatography, Endoscopic Retrograde pankreatoholangiorentgenografiya, Sonography of the digestive tract, hepatosplenography, Ultrasonography of the abdomen, Functional X-ray diagnostics for diseases of the stomach,Functional X-ray diagnosis with bowel diseases,cholangiography, Cholangiography in cholelithiasis, cholangiopancreatography, cholecystography,esophagoscopy, Endoscopic retrograde pancreato, Endoscopic retrograde cholangiopancreatography, Endoscopic intervention, Endoscopic examinations of the digestive system, Endoscopic examination of the lower large intestine, GI Endoscopy, endoscopy, ERCP, Panendoskopiya

N30 Cystitis

urethrocystitis, recurrent cystitis, fibrous cystitis, cystopyelitis, Exacerbation of chronic cystitis, Acute bacterial cystitis

N34 Urethritis and urethral syndrome

Buzhirovanie urethra, Gonococcal urethritis, Urethrocystitis, Gonorrheic urethritis, Urethritis, Non-gonococcal urethritis, Negative urethritis, Lesion of the urethra, Acute gonococcal urethritis, Acute gonorrhea urethritis, Acute urethritis, Infection of the urethra, Bacterial nonspecific urethritis, Bacterial urethritis

N999 * Diagnosis of diseases of the genitourinary system

Angiography of the kidneys, Research of excretory function of the kidneys, Ultrasound for the detection of acquired uterine cavity changes, Replacement of fistulous catheters, Diagnosis of amenorrhea, Evaluation of kidney function and their visualization, Cystoscopy, Vesicology, Intrauterine diagnostic procedures, Urological catheterization, Retrograde urography, Angiography with urinary tract disease, Ultrasound examination of female genital organs, Instrumental studies of pelvic organs, MRI of pelvic organs, Pyelography, Small gynecological manipulations, Ultrasound examination of the genitourinary system, Excretory urography, Colposcopy, Radiography of the genitourinary system, Cystourethroscopy, Cytology of the cervix, Cystography, Cystourethrography, Magnetic resonance imaging of the kidneys, Enlargement of the urethra, Retrograde pyelography, Urethroscopy, Ultrasound of female genital organs, Angiography of the kidney, Mictional urethrocystography

Composition and form of release

Gel for topical application 1 g

Lidocaine hydrochloride 25 mg

Neomycin sulfate 5 mg

Fluocinolone acetonide 0.25 mg

Excipients: sodium carboxymethylcellulose; Sodium citrate; Glycerin (glycerol); Propylene glycol; Methylparahydroxybenzoate; Ethylparahydroxybenzoate; Propyl parahydroxybenzoate; Sodium benzoate; purified water

In an aluminum tube of 10 g; In a pack of cardboard 1 tuba.

Description of dosage form

Transparent, homogeneous, almost colorless gel.

Characteristic

Combined drug.

pharmachologic effect

Pharmacological action - anti-inflammatory, antibacterial, locally anesthetic.

Pharmacodynamics

Lidocaine hydrochloride - has a local anesthetic effect.

Neomycin sulfate is an antibiotic from the group of aminoglycosides with bactericidal action, which has a broad spectrum of antibacterial activity against gram-positive cocci, gram-negative rods, and actinomycetes.

Fluorocinolone acetonide is a synthetic SCS, which has an anti-inflammatory effect when applied topically. Does not affect the antibacterial activity of neomycin and enhances the analgesic effect of lidocaine.

Indication

Diagnostic and therapeutic procedures: cystoscopy, bladder catheterization, urethral expansion, colposcopy, sigmoidoscopy, colonoscopy, etc .;

Acute and chronic nonspecific inflammatory diseases of the lower urinary tract: acute cystitis, exacerbation of chronic cystitis, urethritis;

Infectious and inflammatory diseases of the rectum: hemorrhoids, acute anal fissure, crypts, anusitis, inflammatory skin changes with active fistulas of the rectum.

Contraindications

Hypersensitivity to lidocaine (or other anesthetics of the amide series), neomycin, fluocinolone acetonide or to other components of the drug.

Carefully:

children;

Elderly patients and weakened patients.

pregnancy and lactation

The safety of the drug in pregnant women and during lactation has not been studied. Therefore, the use of the drug Nefluan during pregnancy, especially in its early stages, as well as during breastfeeding, is not desirable or should be carefully justified.

Side effects

Allergic reactions, itching, burning sensation, hyperemia.

Dosing and Administration

In the urethra, rectally.

Diagnostic and medical procedures: the contents are squeezed out of the tube directly into the urethra by squeezing the tube and simultaneously massaging the posterior wall of the urethra. Then, a compressor is applied to the urethra, which is removed after 10 minutes, after which endourethral procedures are performed.

To simplify the administration of the drug and relieve the pain that can occur when the metal part of the tube tip touches the pain zones, a plastic extension is attached to the tube, screwed onto the tube immediately before use. The drug is recommended to enter a few minutes before the start of diagnostic or therapeutic manipulation, as well as immediately after their completion.

The content of one tube is enough to fill the entire urethra, however in some cases the dose can be changed depending on the degree and intensity of the lesion and the effect required.

When carrying out endoscopic studies in proctology (sigmoidoscopy, colonoscopy): the gel is inserted into the anal canal 10-15 minutes before the procedure and again immediately before its beginning.

Infectious-inflammatory diseases of the lower urinary tract: the gel is injected into the urethra 1 or 2 times a day for 5-10 days.

Infectious and inflammatory diseases of the rectum: the gel is applied in the anus and is inserted into the anal canal using an extension (after bowel evacuation and hygienic procedures) 3 times a day for 10-14 days.

special instructions

Efficacy and safety Nefluan, like any other local anesthetic, depends on the correct dosage and techniques of its use.

To prevent side effects, it is necessary to strive to apply the minimum required amount of the drug, which is sufficient to achieve the desired effect. For complete anesthesia of the urethra, when carrying out any instrumental interventions, one Neubuana tube is usually sufficient.

The risk of side effects increases with very long or continuous use of the drug, the use of large doses or in the presence of extensive lesions of the mucous membranes.

Influence on ability to drive vehicles and mechanisms is not established.

storage Conditions

In the dark place at a temperature of 8-30 ° C.

Keep out of the reach of children.

Shelf life

2 years.

Do not use after the expiry date printed on the package.

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