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Instruction for use: Ketanest

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Dosage form: solution for intravenous and intramuscular injection

Active substance: Ketamine*


N01AX03 Ketamine

Pharmacological group:

Anesthetic means

The nosological classification (ICD-10)

Z100.0 * Anesthesiology and premedication: Abdominal surgery; Adenomectomy; Amputation; Angioplasty of the coronary arteries; Carotid artery angioplasty; Antiseptic treatment of skin in wounds; Antiseptic treatment of hands; Appendectomy; Atheroctomy; Balloon coronary angioplasty; Vaginal hysterectomy; Venous bypass; Interventions on the vagina and cervix; Interventions on the bladder; Interference in the oral cavity; Reconstructive-reconstructive operations; Hand hygiene of medical personnel; Gynecological Surgery; Gynecological interventions; Gynecological operations; Hypovolemic shock during surgery; Disinfection of purulent wounds; Disinfection of the edges of wounds; Diagnostic Interventions; Diagnostic procedures; Diathermocoagulation of the cervix; Long-term surgeries; Replacement of fistulous catheters; Infection in orthopedic surgical interventions; Artificial heart valve; Kistectomy; Short-term outpatient surgery; Short-term operations; Short-term surgical procedures; Cryotyreotomy; Blood loss during surgical interventions; Bleeding during surgery and in the postoperative period; Laser coagulation Laserocoagulation; Laser retinopathy of the retina; Laparoscopy; Laparoscopy in gynecology; Likvornaya fistula; Small gynecological operations; Small surgical interventions; Mastectomy and subsequent plastic surgery; Mediastinotomy; Microsurgical operations on the ear; Mukinging operations; Suturing; Minor surgery; Neurosurgical operation; Eclipse of the eyeball in ophthalmic surgery; Orchiectomy; Pancreatectomy; Pericardectomy; The rehabilitation period after surgical operations; Reconvalence after surgical intervention; Percutaneous transluminal coronary angioplasty; Pleural Thoracocentesis; Pneumonia postoperative and post traumatic; Preparing for surgical procedures; Preparing for a surgical operation; Preparation of the surgeon's arms before surgery; Preparation of the colon for surgical interventions; Postoperative aspiration pneumonia in neurosurgical and thoracic operations; Postoperative nausea; Postoperative hemorrhage; Postoperative granuloma; Postoperative shock; Early postoperative period; Myocardial revascularization; Resection of the apex of the tooth root; Resection of the stomach; Bowel resection; Resection of the uterus; Liver resection; Small bowel resection; Resection of a part of the stomach; Reocclusion of the operated vessel; Gluing of tissues during surgical interventions; Suture removal; Condition after eye surgery; Condition after surgery in the nasal cavity; Condition after gastrectomy; Condition after resection of the small intestine; Condition after tonsillectomy; Condition after removal of duodenum; Condition after phlebectomy; Vascular Surgery; Splenectomy; Sterilization of surgical instrument; Sterilization of surgical instruments; Sternotomy; Dental surgery; Dental intervention on periodontal tissues; Strumectomy; Tonsillectomy; Thoracic surgery; Total gastrectomy; Transdermal intravascular coronary angioplasty; Transurethral resection; Turbinectomy; Removal of a tooth; Cataract removal; Removing Cysts; Removal of tonsils; Removal of myoma; Removal of mobile milk teeth; Removal of polyps; Removal of a broken tooth; Removal of the uterus; Removal of seams; Urethrotomy; Fistula of the luminal ducts; Frontoetmoidogamotomy; Surgical infection; Surgical treatment of chronic ulcers of extremities; Surgery; Surgery in the anus; Surgery on the large intestine; Surgical practice; Surgical procedure; Surgical interventions; Surgical interventions on the digestive tract; Surgical interventions on the urinary tract; Surgical interventions on the urinary system; Surgical interventions on the genitourinary system; Surgical intervention on the heart; Surgical procedures; Surgical operations; Surgical operations on veins; Surgical intervention; Vascular Surgery; Surgical treatment of thromboses; Cholecystectomy; Partial resection of the stomach; Extraperitoneal hysterectomy; Percutaneous transluminal coronary angioplasty; Percutaneous transluminal angioplasty; Coronary artery bypass grafting; Extirpation of the tooth; Extirpation of infant teeth; Extirpation of pulp; Extracorporeal circulation; Extraction of the tooth; Extraction of teeth; Extraction of cataracts; Electrocoagulation; Endourological interventions; Episiotomy; Ethmoidotomy; Complications after tooth extraction

Composition and release form

1 ml solution for injection contains ketamine hydrochloride 10 or 50 mg; in ampoules of 2 and 5 ml, in cardboard boxes 10 pcs. or in bottles of 20 and 10 ml, in cardboard boxes 5 and 1 pc. respectively.

Pharmachologic effect

Pharmacological action - analgesic, anesthetic.


Causes a pronounced analgesic effect, not enough to relax the skeletal muscles.

Clinical Pharmacology

After IV and / or injection, the effect develops in 30-60 seconds and 2-4 minutes (up to 6-8 minutes), respectively, and lasts 5-10 minutes (up to 15 minutes) or 12-25 minutes (up to 30-40 min.).

Indications of the drug Ketanest

Introductory and basic anesthesia; anesthesia with short-term surgical interventions, painful instrumental and diagnostic manipulations (including treatment of burn surface, transportation of patients, etc.).


Disorders of cerebral circulation; Arterial hypertension, angina pectoris, cardiovascular insufficiency in the stage of decompensation; preeclampsia and eclampsia, epilepsy in childhood.

Side effects

Increased pulse, increased blood pressure; rhythm disturbances (rarely - depression) of breathing; psychomotor agitation and hallucinations upon withdrawal from anesthesia, hypersalivation; soreness and congestion along the veins.


It is pharmaceutically incompatible with barbiturates (you can not inject it in one syringe).

Dosing and Administration

Parenterally, the dose is set individually. IV, jet, slowly (at least 60 seconds) - in the initial dose - 0.7-2 mg / kg body weight (the operation can begin no earlier than 30 seconds); IM - in an initial dose of 4-8 mg / kg or 3-5 mg / kg - when administered in several places (the operation starts after a few minutes); to prolong the effect, the administration is repeated iv or IM in a half or full dose. IV, drip - at a speed of 80-100 drops / min.


Stop breathing. Treatment - IVL.

Precautionary measures

With caution appoint with increased intracranial and spinal pressure, kidney disease.

Conditions for storing Ketanest

At room temperature.

Keep out of the reach of children.

Shelf life of Ketanest

3 years.

Do not use after the expiry date printed on the package.

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