Instructions / Instruction for use: CoxibI want this, give me price
Active substance Celecoxib
ņ“’ M01AH01 Celecoxib
NSAIDs - Coxiba
Nosological classification (ICD-10)
M06.9 Other specified rheumatoid arthritis
Rheumatoid arthritis,Pain syndrome in rheumatic diseases, Pain in rheumatoid arthritis, Inflammation in rheumatoid arthritis, Degenerative forms of rheumatoid arthritis, Children's rheumatoid arthritis, Exacerbation of rheumatoid arthritis, Acute articular rheumatism, Rheumatic arthritis, Rheumatic polyarthritis, Rheumatoid arthritis, Rheumatic polyarthritis, Rheumatoid arthritis, Rheumatoid arthritis of active course, Rheumatoid arthritis, Rheumatoid polyarthritis, Acute rheumatoid arthritis, Acute rheumatism
Composition and form of release
1 capsule contains celecoxib 100 or 200 mg; in a contour acheive box 10 pcs., in a cardboard bundle 3 packs.
Pharmacological action - anti-inflammatory, analgesic.
Selectively inhibits cyclooxygenase-2 and blocks the formation of pro-inflammatory PG (in particular, prostaglandin E2). In therapeutic doses does not affect the activity of human cyclooxygenase-1 and thus does not disrupt normal physiological processes involving prostaglandins, particularly in the mucous membrane of the stomach, intestines and platelets.
In controlled clinical trials, it was noted that the incidence of gastrointestinal complications did not differ from placebo and was significantly lower than with non-specific cyclooxygenase inhibitors.
Deforming osteoarthritis, rheumatoid arthritis (symptomatic treatment of pain and inflammatory syndrome).
Hypersensitivity (including sulfanilamides), allergic reactions associated with taking acetylsalicylic acid and other NSAIDs, gastric ulcer and duodenal ulcer in the acute stage, I and III trimester of pregnancy, breastfeeding.
Abdominal pain, diarrhea, dyspepsia, flatulence, nausea, headache, dizziness, insomnia, pharyngitis, rhinitis, sinusitis, anemia, peripheral edema, leg cramps, allergic reactions in the form of skin rashes, itching.
Antacids reduce absorption from the gastrointestinal tract, fluconazole - the concentration of the drug in the plasma.
Simultaneous use with warfarin increases the risk of hemorrhagic complications.
Dosing and Administration
Inside. With deforming osteoarthritis, 200 mg once a day or 100 mg twice a day; if necessary, up to 400 mg / day in 2 divided doses; with rheumatoid arthritis - 200-400 mg / day in 2 divided doses.
Clinical data on the use of the drug in patients with severe impairment of liver and kidney function, as well as in people under 18 years of age are absent.
The drug is in the process of registration.
In a dry, the dark place at a temperature of no higher than 25 į C.
Keep out of the reach of children.
Do not use after the expiry date printed on the package.