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DR. DOPING

Instructions

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Instruction for use: Vaccine herpes

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Trade name of the drug – Vitaherpavac, Herpovax

The Latin name of the substance Vaccine herpes

Vaccinum ad prophylaxim herpetis (genus. Vaccini ad prophylaxim herpetis)

Pharmacological group:

Vaccines, serums, phages and toxoids

Model clinical-pharmacological article 1

Characteristic. The inactivated herpes simplex virus I and II antigenic types, obtained by reproduction in Vero B cell culture, lyophilized. Contains gentamycin sulfate not more than 40 μg / ml, stabilizer-sucrose in a final concentration of 0.075 g / ml and gelatin at a final concentration of 0.01 g / ml, formaldehyde at a final concentration of 200 μg / ml

Pharmacotherapy. Stimulates cellular mechanisms of resistance of the human body to the herpes simplex virus type I and II.

Indication. Prevention of recurrence of herpetic infection.

Contraindications. Hypersensitivity to gentamicin and other antibiotics of the aminoglycoside group, herpetic infection in the active stage (vaccination is given no earlier than 5 days after the disappearance of clinical manifestations, with ophthalmoherpes - no earlier than 1 month), acute (infectious and non-infectious) diseases , Chronic diseases in Art. Exacerbation or decompensation, malignant neoplasms, pregnancy.

Dosing. Intracutaneously the area of the inner surface of the forearm in a single dose of 0.2 ml (control - the formation of "lemon crust").

The course of vaccination for herpes infections of the skin and mucous membranes - 5 injections, which are carried out with an interval of 7 days.

Patients with complicated herpetic infection 2nd and subsequent injections are repeated with an interval of 10 days.

After 6 months, a second course of vaccination (5 injections) is performed.

The contents of the vial are dissolved in 0.3 ml of solvent (water for injection). To do this, the solvent is poured into the vial of the vaccine using a syringe with a needle, which is then shaken until the contents are completely dissolved.

Side effect. General: a slight increase in temperature, weakness.

Local reaction: skin hyperemia with a diameter of up to 2 cm during the first day and a slight short-term burning (normal reaction of the body to the introduction of the vaccine).

Special instructions. Vaccination is carried out in medical institutions (inpatient, dispensary, polyclinic) under the supervision of a doctor.

Vaccination is carried out in Art. Remission, no earlier than 5 days after the complete disappearance of clinical manifestations of herpetic infection. If more severe local and general reactions occur or the main process becomes aggravated, vaccination should be discontinued. Vaccination can be continued after the complete disappearance of clinical manifestations of the overall response to the introduction of the vaccine.

All cases of more pronounced local and general reactions in the patient should be examined by a physician and listed in the relevant document. Dissolved drug should be a slightly opalescent liquid pink.

The preparation is not suitable for use in vials with broken integrity, marking, when the color changes, with expired shelf life, if stored incorrectly. The dissolved vaccine is not subject to storage.

Opening of the vial, dissolution of the drug and the vaccination procedure are carried out with strict adherence to aseptic rules.

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