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Instruction for use: Tramazoline (Tramazolinum)

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chemical name 4,5-Dihydro-N- (5,6,7,8-tetrahydro-1-naphthalenyl) -1H-imidazol-2-amine

Pharmacotherapeutic group:

Alpha-adrenoceptor agonists


The nosological classification (ICD-10)

H66.9 Otitis media, unspecified

Chronic otitis, Otitis, otitis media, middle ear infections, Otitis media in children

J01.9 Acute sinusitis, unspecified

Allergic sinusitis, Pain in sinusitis,Inflammation of the sinuses, catarrhal sinusitis, polypoid sinusitis, Sinusitis, acute sinusitis, genyantritis, purulent sinusitis

J30.1 Allergic rhinitis caused by the pollen

hay fever, Hypersensitivity to pollen, Polypoid allergic rhinosinusitis, Seasonal hay fever, rhinitis

J31.0 Chronic Rhinitis

Hyperplastic chronic Rhinitis, polypoid rhinosinusitis, Atrophic rhinitis with crusting, Hypertrophic rhinitis, Runny fetid, Rhinitis hyperplastic, chronic Rhinitis, Rhinitis chronic atrophic fetid, Rhinitis chronic atrophic simple, Rhinitis chronic hypertrophic, Exacerbation of chronic rhinitis, Chronic atrophic rhinitis, Dry rhinitis

J32.9 Chronic sinusitis, unspecified

polypoid rhinosinusitis, Inflammation of the sinuses, Inflammation of the lateral sinuses

CodeCAS 1082-57-1

Pharmacological Properties of TramazolinePharmachologic effect
alpha adrenostimuliruyuschee means; It has a vasoconstrictor effect. It reduces swelling of nasal mucosa, nasal congestion during "cold", and hay fever. Onset of action - 5 minutes, duration - 8-10 hours.

Indications for Tramazoline
Rhinitis, hay fever, sinusitis, otitis media with evstahiitom.

Contraindications for Tramazoline

Hypersensitivity, atrophic rhinitis, children's age (up to 6 years).


Angle-closure glaucoma, pregnancy, lactation.


Intranasal, up to 4 times a day in each nostril. The course of treatment - no more than 5-7 days.

Side effect

swelling of the nasal mucosa, burning, copious, nausea, dizziness, headache, disturbance of taste sensitivity, palpitations, increased blood pressure. With prolonged use - rhinitis, nasal congestion, mucosal atrophy.

Overdose of Tramazoline
Symptoms: fatigue, dizziness, nausea, insomnia, increased blood pressure, tachycardia, fever, shock, reflex bradycardia.


In combination with antidepressants and MAO inhibitors increases the risk of hypertension.

Special instructions

Avoid contact with eyes. If after 7 days of therapy, positive dynamics is not observed, you should seek medical advice. After removing the protective cap before use to make multiple injections into the air, until the spray cloud sustainable. Before injection clean the nose of the content, after extraction of the tip produces a normal breath through the nose.

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