Instruction for use: Tonocardin

Trade name of the drug –Tonocardin

Active substance: Doxazosinum

Dosage Form: tablets

Composition (per tablet): active substance: doxazosin mesylate 2.43 mg; 4.86 mg (Equivalent to 2 mg of doxazosin and 4, respectively)

Excipients: sodium carboxymethyl - 1.2 / 2.4 mg; MCC - 75.17 / 150.34 mg; lactose - 40/80 mg; magnesium stearate - 1.08 / 2.16 mg; Sodium lauryl sulfate - 0.12 / 0.24 mg

Pharmacotherapeutic group: Alpha-blockers

Drugs affecting the metabolism of the prostate gland and correctors urodynamics

ATX C02CA04 Doxazosin

The nosological classification (ICD-10)

I10 Essential (primary) hypertension: hypertension; Arterial hypertension; Arterial hypertension crisis course; Essential Hypertension; Essential hypertension; Essential hypertension; Essential hypertension; Essential hypertension; Primary hypertension; Arterial hypertension, complications of diabetes; The sudden increase in blood pressure; Hypertensive disorders of blood circulation; hypertensive condition; hypertensive crises; arterial Hypertension; malignant Hypertension; Hypertonic disease; hypertensive crises; accelerated hypertension; malignant hypertension; The aggravation of hypertensive disease; Transient hypertension; Isolated systolic hypertension

I15 Secondary hypertension: Arterial hypertension, complications of diabetes; hypertension; The sudden increase in blood pressure; Hypertensive disorders of blood circulation; hypertensive condition; hypertensive crises; hypertension; arterial Hypertension; malignant Hypertension; hypertensive crises; accelerated hypertension; malignant hypertension; The aggravation of hypertensive disease; Transient hypertension; hypertension; Arterial hypertension; Arterial hypertension crisis course; renovascular hypertension; Hypertension symptomatic; Renal hypertension; Renovascular hypertension; renovascular hypertension; Symptomatic hypertension

N40 Hyperplasia of prostate gland: Prostate adenoma; BPH; Prostatauxe; prostate Hypertrophy; Dysuric disorders caused by benign prostatic hyperplasia; Dizuricheskie disorder with benign prostatic hyperplasia; Dysuria with prostate cancer; Benign prostatic giperpalaziya; Benign prostatic hyperplasia; Benign prostatic hyperplasia stages 1 and 2; Benign prostatic hyperplasia I degree; Benign prostatic hyperplasia II degree; Benign prostatic hypertrophy; The disease of the prostate gland; Acute urinary retention related to benign prostatic hyperplasia; Benign prostatic hyperplasia stages 1 and 2 in combination with prostatitis; paradoxical ischuria

Pharmacological Properties of Tonocardin

Pharmachologic effect - Mode of action - hypotensive.

Tonocardin Dosage and Administration

Inside, 1 time a day (morning or evening), regardless of the meal, not chewing and drinking plenty of water.

Benign prostatic hyperplasia

The initial dose is 1 mg / day, in order to minimize the possibility of orthostatic hypotension / or fainting. If necessary, depending on the performance and availability of urodynamics BPH symptoms increase the dose (1-2 week intervals) to 2.4 mg / day. The maximum permissible dose is 8 mg / day.

The recommended maintenance dose - 2-4 mg / day.

Arterial hypertension

The initial dose is 1 mg / day at bedtime. After the first dose the patient should be in bed for 6-8 hours. It is required in connection with the development of the first dose of the phenomenon, especially pronounced on the background of the previous diuretics.

When insufficient therapeutic effect daily dose can be increased to 2 mg every 1-2 weeks. Subsequently, every 1-2 weeks the dose can be increased to 2 mg. The vast majority of patients, the optimal therapeutic effect is achieved at a dose of 8 mg / day. The maximum daily dose of 16 mg / day should not be exceeded.

After reaching a stable therapeutic effect of the dose is usually reduced (the average therapeutic dose is usually 2-4 mg / day during maintenance therapy).

The drug Tonokardin take long. Duration of treatment is determined by the physician.

Release form

Tablets, 2 mg, 4 mg. According to Table 10. in a blister (PVC / PVDC / aluminum foil); 2 blisters in a carton box.

Manufacturer

Pliva Hrvatska d.o.o

Barun Filipovich Prilaz 25, 10000 Zagreb, Republic of Croatia.

Address for receipt of claims: 119049, Moscow, st. Shabolovka, 10, Bldg. 1.

Tel .: (495) 644-22-34; fax: (495) 644-22-35 / 36.

Storage conditions of Tonocardin

The temperature is not above 25 ° C.

Keep out of the reach of children.

Shelf life

4 years.

Do not use beyond the expiration date printed on the package.

Conditions of supply of pharmacies

On prescription.