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Instruction for use: Tevacomb

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Active substance Salmeterol + Fluticasone

ATX Code R03AK06 Salmeterol + Fluticasone

Pharmacotherapeutic group:

Bronchodilator combination means (beta2-agonists selective glucocorticosteroid + local) [beta-adrenergic agonist in combination]

The nosological classification (ICD-10)

J44.9 Chronic obstructive pulmonary disease, unspecified

Obstructive pulmonary diseases, Bronchial obstruction, bronchial obstruction, Exacerbation of chronic obstructive pulmonary disease, reversible airflow obstruction, Reversible airway obstruction, panbronchiolitis, Panbronhit, COPD, Chronic pulmonary infection, Chronic infection of the lower respiratory tract, Chronic obstructive pulmonary disease, Chronic obstructive pneumonia, Chronic lung disease, Chronic obstructive pulmonary disease, Chronic bronchopulmonary disease, Chronic broncho-pulmonary diseases, Airway obstruction

J45 Asthma

Asthma physical effort, status asthmaticus, Bronchial asthma, Asthma lung flow, Bronchial asthma with obstruction of sputum discharge, Bronchial asthma heavy currents, Bronchial asthma physical effort, hypersecretory asthma, Hormone-dependent form of bronchial asthma, Relief of asthma attacks in bronchial asthma, Non-allergic asthma, nocturnal asthma, Exacerbation of asthma, Asthma attacks, Endogenous forms of asthma, Night asthma, Cough with bronchial asthma

Structure and Composition

Aerosol for inhalation dose 1 dose

active substance:

salmeterol (salmeterol xinafoate in the form) 0.025 / 0.025 / 0.025 mg

Fluticasone propionate 0.050 / 0.125 / 0.250 mg

Excipients: ethanol - 1,560 / 1,560 / 1,560 mg; Lecithin - 0.00001725 / 0.000032 / 0.00005726 mg; tetrafluoroethane - 76.354 / 76.279 / 76.154 mg

pharmachologic effect


Dosing and Administration


Bronchial asthma

Adults and adolescents over 12 years

Preparation Tevakomb 25 .mu.g / 50 .mu.g - 2 inhalation dose 2 times a day.

Preparation Tevakomb 25 g / 125 g - 2 inhalation dose 2 times a day.

Preparation Tevakomb 25 g / 250 g - 2 inhalation dose 2 times a day.

Children from 4 to 12 years

Preparation Tevakomb 25 .mu.g / 50 .mu.g - 2 inhalation dose 2 times a day.


Preparation Tevakomb 25 g / 125 g - 2 inhalation dose 2 times a day.

Preparation Tevakomb 25 g / 250 g - 2 inhalation dose 2 times a day.

The drug is prescribed in the smallest effective dose, which provides control of symptoms. In achieving the effect of the drug by 2 times daily dose is advisable to reduce to the minimum or effective to switch to a lower dosage, frequency of application - 1 time per day. The amount of fluticasone in your chosen form must match the severity of the disease.

the drug is used regularly for optimum effect, even in the absence of symptoms of asthma and COPD. The course of treatment and the dose the doctor sets individually.

There is no need for dose adjustment in elderly patients and in patients with liver disease or kidney disease.

Terms of use inhaler

The drug Tevakomb placed in an aluminum bottle with a metering valve, fitted with inhalation device with a protective cap. The inhalation device may comprise a dose counter.

1. Remove the inhalation device with protective cap and ensure that the output tube inhalation device clean. Hold the inhalation device between the index finger and thumb in a vertical position, with the thumb should be placed on the bottom of the inhalation device, and the index finger - on the bottom of an aluminum can.

2. Shake the aluminum cylinder up and down. (In the case where the inhalation device includes a dose counter, before first use, to locate it away from the face and make two pressing in air to release the 2 doses. Counter doses show the number "120" - the number of units, located in the cylinder. Now inhaler ready for further use).

3. Take a deep breath through your mouth. Firmly pinch the outlet tube of the inhalation device.

4. Make a slow, deep breath. The inhalation time press the index finger on the bottom of an aluminum cylinder, releasing a dose of the drug Tevakomb, continue to slowly inhale.

5. Remove the inhalation device from the mouth and hold your breath for 10 seconds or at a time that does not cause the patient discomfort. Slowly exhale.

6. After inhalation, rinse your mouth with water, being careful not to swallow the spray, which fell during inhalation on oral mucosa.

7. If you want to enter more than one dose, wait 1 minute and repeat all the steps, starting with the 2nd step, the finishing step 6.

8. Close the inhalation device protective cap.

In steps 3 and 4 should not be rushed. At the time of release dose medication is important to breathe in as slowly as possible. Which should be trained about the mirror. If there was a noticeable "steam" coming from the top of a container or out of the corners of the mouth, it is necessary to start again from step 2.

Cleaning the inhaler

The inhalation device should be cleaned at least once a week.

The inhalation device without a counter doses

Remove the aluminum cylinder of the inhalation device. Carefully rinse the inhalation device and a protective cap with warm water. Do not use hot water! Shake the inhalation device and a protective cap to remove the remaining water and dry them without the use of heating devices.

Do not immerse the aluminum cylinder in the water!

Inhaler device with a dose counter

Remove the protective cap from the inhalation device, but do not remove the aluminum can out of it! Wipe clean with a dry cloth inside and outside of the inhalation device and its outlet pipe. Put back the protective cap.

Warning: Do not wash or rinse in water or one part of the inhaler!

Information about the dose counter. Dose counter displays the number of doses in the canister. In use of the inhaler, the counter digit decrease, and the counter indicates the number of doses remaining in the canister. When the cylinder is 40 doses, the color of the counter changes from green to red. This shows that the cylinder is not much and the patient doses should think about a new inhaler. When the dose counter displays the digit "0", it means that the bottle is no longer of the drug and the patient needs a new inhaler. It may seem that the tank is not yet empty, but its further use the patient does not receive the correct amount of medication.

release Form

Aerosol for inhalation dose, 25/50 mg / dose, 25/125 mg / dose, 25/250 mg / dose. At doses of 120 aluminum cylinder with a dosing valve, with the inhalation device fitted with a protective cap 120 doses or an aluminum canister with a metering valve provided with inhalation device with a dose counter and a protective cap.

On 1 cylinder in a carton box. To control the first opening each pack can be wrapped in a transparent polyethylene film having a tear tape.

Storage conditions

The temperature is not above 30 C (do not freeze).

Keep out of the reach of children.

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