Instruction for use: Sotalex

Active substance: Sotalol

ATX Code C07AA07 Sotalol

Pharmacotherapeutic group:

Beta-blockers

Structure and Composition

Tablets 1 tab.

sotalol hydrochloride 160 mg

Excipients: lactose monohydrate; stearic acid; magnesium stearate; corn starch; Colloidal anhydrous silica; MCC

Blister of 10 pcs .; in box 3 blisters.

Pharmacological Properties
Pharmachologic effect

antiarrhythmic.

Dosing and Administration

Inside for 1-2 hours before eating.

At the beginning of treatment is recommended to take 160 mg per day in 2 divided doses (approximately 12 hours). This dose can be increased if necessary after appropriate clinical evaluation of the patient, or 320 to 240 mg per day. In most patients, therapeutic response is achieved at a total daily dose of 160-320 mg, divided into 2 doses. Some patients with life-threatening refractory ventricular arrhythmias may require up to 480-640 mg per day; However, such doses may be administered only if the potential benefit outweighs the increased risk of side effects, especially proaritmogennoe Action, patients with cardiomyopathy or congestive heart failure with angina, hypertension, conditions after myocardial infarction is recommended to begin treatment in the hospital. The starting dose is 160 mg daily in 1 or 2 divided doses. After a week at the dose can be increased to 80 mg / day, if necessary (see Table 1.2. 160 mg) at weekly intervals. The rate of increase in the dose depends on the tolerability of the drug in patients who, in particular, was evaluated by the degree of induced bradycardia, and clinical response. Due to the relatively prolonged T1 / 2 for most patients, Sotaleks® effective when administered one time per day. Dose interval - 160-320 mg / day.

Use in patients with impaired renal function. Since sotalol excreted primarily in the urine, and its T1 / 2 is increased in the presence of renal failure, the dosage should be reduced if the level of serum creatinine over 120 mmol / l

Storage conditions

At a temperature of 15-25 ° C.

Keep out of the reach of children.

shelf life

3 years.

Do not use beyond the expiration date printed on the package.