Instruction for use: Solcoseryl Dental Adhesive Paste

Trade name of the drug – Solcoseryl dental adhesive paste

Dosage form: paste for local application

Composition.
Composition per 1 g
Active ingredients: Solcoseryl - deproteinized dialysate from the blood of healthy dairy calves (Bos Taurus),standardized chemically and biologically (In terms of dry matter) 2.125 mg
Polidocanol 10,000 600 mg
Preservatives
Methyl parahydroxybenzoate (E 218) 1.800 mg
Propyl parahydroxybenzoate (E 216) 0.200 mg
Excipients
22.875 mg Sodium carboxymethyl cellulose
Peppermint Oil 2,925 mg
Menthol 0,075 mg
The base paste
(Sodium carboxymethylcellulose, gelatin, pectin,
PE 350.000, liquid paraffin) 960,000 mg

Description
Pale beige granular homogeneous, easy to distribute mass with the smell of peppermint.

Pharmacotherapeutic group- The stimulator of tissue regeneration.
ATC code ÀÎ1AD11

Pharmacological Properties

Solcoseryl - chemically and biologically standardized deproteinized dialysate prepared from blood of healthy dairy calves ultrafiltration. Solkoseril contains a wide range of natural compounds of low molecular weight up to 5000 Daltons: glycolipids, nucleosides and nucleotides, amino acids, oligopeptides, trace elements, electrolytes, intermediate products of carbohydrate and fat metabolism. Solcoseryl activates the transport of oxygen and nutrients at the cellular level, oxygen consumption increases the cell and stimulates the ATP synthesis, enhances proliferation of reversibly injured cells, particularly under hypoxic conditions, thereby accelerating wound healing processes. Solcoseryl stimulates angiogenesis, promotes revascularization of ischemic tissues, and - the creation of favorable conditions for the synthesis of collagen and growth of fresh granulation tissue, accelerates re-epithelialization and wound closure. Solcoseryl also has membrane stabilizing and cytoprotective action.
Polidocanol 600 - local anesthetic; It is acting in the peripheral nerves, causing their reversible blocking. It provides a fast and long-lasting local anesthetic effect. After applying the paste to the oral mucosa pain docked 2-5 minutes; anesthesia is maintained for 3-5 hours.
Solcoseryl dental adhesive paste forms a protective layer on the therapeutic oral mucosa of the affected area of the mouth and protects it from mechanical and chemical damage for 3-5 hours, performing the function of medicinal bandage.

Pharmacokinetics
Not studied.

Indications
Solcoseryl dental adhesive paste used in patients of all age groups for the local acceleration of wound healing, pain relief and protect the wound surface for the following diseases and conditions:

• Gingivitis and periodontal disease, including after surgery, the implant, removal of tartar
• Pressure sores from dentures in adaptation to it
• Alveolitis
• Stomatitis
• Lesions of the oral mucosa with pemphigus
• Aphthae
• bridou

Contraindications
Individual sensitivity to any of the formulation components, including free parahydroxybenzoic acid (E 210), the presence of residual amounts of characteristics which is caused in the production process of the preparation.
Dosing and Administration
A preparation for topical application in the oral mucosa.
Mucous membrane surface must be pre-dried with a cotton or gauze swab. A strip of paste a length of about 0.5 cm to put, not rubbing, the mucous thin layer using a finger or a cotton swab, and then lightly moisten applying a paste with water. The procedure is repeated 3-5 times a day after meals and before bedtime. Treatment is carried out until symptoms disappear.
Solcoseryl dental adhesive paste forms a protective layer on the therapeutic oral mucosa of the affected area of the mouth and protects it from mechanical and chemical damage for 3-5 hours. When applying the paste to the unseasoned mucosa may decrease the duration of therapeutic effects.In the treatment of pressure sores from dentures paste is applied to a dry denture and moisten with water.
Recommended course dose of the drug - 1 tube (5 g).

Side effect
Change of taste sensations.
Allergic reactions (local edema), in which case the need to stop using the product and seek medical advice.

Overdose (intoxication) drug
For information about the effects of overdose are not available.

Special Instructions

Do not lay Solcoseryl dental adhesive paste in the wound cavity formed by the removal of molars, wisdom teeth, as well as - apicotomia (resection of apex) in the case of a tooth hole edges shrink, followed by suturing.
Solcoseryl dental adhesive paste contains not contain anti-infective components. In the case of an acute infection of the affected area of the mucous membranes of the mouth, which is to be treated with this drug, it is necessary to conduct preliminary medical treatment / processing of the affected area, to eliminate the symptoms of inflammation.
Use of the drug during pregnancy, lactation, children and the elderly.
There are no contraindications to the use of the drug Solcoseryl dental adhesive paste during pregnancy and lactation, although special controlled safety studies of the drug in women during pregnancy and lactation have not been conducted.
In respect of the children are not limitations of the preparation.
With regard to use of the drug in elderly patients there is no limit.

Interaction with other drugs
So far, no cases have been identified interaction Solcoseryl dental adhesive paste with other drugs.
When concomitant administration Solcoseryl dental adhesive paste and other drugs in the form of rinses, the paste should be applied after the application of these drugs.

Release Form
5 g aluminum tubes. Tuba, together with instructions for use can be embedded in a cardboard box.
Storage conditions
Store at temperatures below 30 ° C out of reach of children.
Granular-dryish paste consistency allows its optimal adhesive properties, and does not indicate a deterioration in the quality of the drug. With the opening of the tube can be released oil that also does not indicate a deterioration in the quality of the drug.
Shelf life
4 years. Do not use the drug after the expiry date stated on the package.
Conditions of supply of pharmacies
Without recipe.