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DR. DOPING

Instructions

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Instruction for use: Riboxin Pills

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Trade name of the drug Riboxin

International nonproprietary name: Inosine

Dosage Form: film-coated tablets,
Composition:

Each tablet contains:
Active ingredient: inosine (Riboxinum) - 200 mg
Excipients: potato starch, refined sugar (sucrose), povidone (polyvinylpyrrolidone or low-molecular weight clinical plasdon), stearic acid, magnesium stearate
film coating composition: hydroxypropylcellulose (giproloza), titanium dioxide, talc, polyethylene glycol (Macrogol 4000) tropeolin O (O tropeolin dye).

Description:
Tablets round shape, biconvex, film-coated, from light yellow to yellow-orange. The cross section shows two layers, the inner layer color - white.
Pharmacotherapeutic group:metabolic means

ATX Code 01EB

Pharmacological Properties

Pharmacodynamics.

Metabolic means a precursor of adenosine triphosphate; It provides anti-hypoxic, metabolic and antiarrhythmic action. Increases myocardial energy balance, improves coronary circulation, prevents the effects of intraoperative renal ischemia. Directly involved in the metabolism of glucose and helps to activate the metabolism in hypoxic conditions and in the absence of ATP. It activates the metabolism of pyruvic acid to ensure the normal process of tissue respiration, and promotes activation of xanthine dehydrogenase. It stimulates the synthesis of nucleotides, enhances the activity of some enzymes of the Krebs cycle. Penetrating the cells increases the energy level has a positive effect on metabolic processes in myocardium - heart rate increases strength and enhances the myocardial diastolic relaxation, thereby increasing the stroke volume. Reduces platelet aggregation activates the regeneration of tissues (especially myocardial mucosa and gastrointestinal tract).

Pharmacokinetics.

It is well absorbed in the gastrointestinal tract. It is metabolized in the liver with the formation of glucuronic acid and its subsequent oxidation. The small amount excreted in the urine.

Indications
Assign an adult in the treatment of coronary heart disease, myocardial dystrophy, myocardial infarction, cardiac arrhythmias associated with the use of cardiac glycosides. Assign with hepatitis, cirrhosis, fatty liver caused by alcohol or drugs.

Contraindications
Hypersensitivity to the drug, gout, hyperuricemia.Precautions - Renal Failure.

Dosing and Administration

Assign inside before a meal. The daily dose ingestion of 0.6-2.4 in the first days of treatment the daily dose is 0.6-0.8 g (200 mg 3-4 times a day). If the dose is increased tolerability (on day 2-3) and 1.2 g (400 mg 3 times daily), if necessary - up to 2.4 g per day. Duration - from 4 weeks to 1.5-3 months. When urokoproporfirii daily dose is 0.8 g (200 mg four times a day). The drug is taken daily for 1-3 months.

Side effects
Allergic reactions such as urticaria, pruritus, flushing of the skin (requires removal of the drug). Occasionally a drug for the treatment increases the concentration of uric acid in the blood and increase gout (with prolonged use).

Release Form
Tablets, film-coated 200 mg. 10 tablets in blisters of PVC film and aluminum foil. On 2, 3 or 5, the contour of cellular packaging along with instructions for use are placed in a pile of cardboard.

Storage conditions
Store in a dry, dark place at a temperature no higher than 25 C. Keep out of the reach of children.

Shelf life
3 years. Do not use after the expiration date printed on the package.
Conditions of supply at the pharmacy
On prescription.

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