Instruction for use: Relief
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Trade name of the drug – Relief
Active substance: Phenylephrine
ATX code C05AX03 Drugs for the treatment of hemorrhoids and anal fissures in combination
Pharmacotherapeutic group:
Means the treatment of hemorrhoids [alpha agonists]
The nosological classification (ICD-10)
I84 Hemorrhoids
Painful hemorrhoids, External hemorrhoids, Internal hemorrhoids, Inflammation of hemorrhoids, Aggravation of hemorrhoids, Chronic bleeding hemorrhoids, Acute hemorrhoidal attack
K60 Fissure and fistula of anus and rectum
Anal fissure, Acute anal fissure, paraproctitis chronic, perianal crack, Surface anal fissure, Fistulas of the rectum, Crack rectum, Cracks anal area, Cracks anus, Cracks rectum, Chronic anal fissures, Chronic periproktit, Sentry bump
L29.0 anus Itching
Anal eczema, Anal itching, anogenital pruritus, Dermatitis and eczema in the anal area, Perianal dermatitis, anal Itching, Itching anogenital, Itching anorectal, Itching in the genital area and the anus, Itching in the anus, Eczema anal area, perianal dermatitis
Composition
Rectal Suppositories 1 supp.
active substance:
phenylephrine hydrochloride 5 mg
Other ingredients: cocoa bean oil - 1770 mg; corn starch - 224.2 mg; methyl parahydroxybenzoate - 0.4 mg; propyl parahydroxybenzoate - 0.4 mg
Ointment for rectal and external application of 1 g
active substance:
phenylephrine hydrochloride 2.5 mg (0.25%)
Excipients: mineral oil - 140 mg (14%); Petrolatum - 749 mg (74.9%); methyl parahydroxybenzoate - 2 mg (0.2%); propyl parahydroxybenzoate - 1 mg (0.1%); anhydrous lanolin - 23.5 mg (2.35%); benzoic acid - 2 mg (0.2%); Corn oil - 2 mg (0.2%); glycerol - 25 mg (2.5%); lanolin alcohol - 15 mg (1.5%); paraffin - 5 mg (0.5%); Purified water - 19 mg (1.9%); Thymus vulgaris oil grass - 1 mg (0.1%); vitamin E (alpha-tocopherol acetate) - 0.5 mg (0.05%); beeswax white - 12.5 mg (1.25%)
Description
Suppositories: opaque, from nearly white to pale yellow, torpedo-shaped.
Ointment: yellow uniform, free from contamination.
Pharmacological Properties of ReliefPharmachologic effect
vasoconstrictor, alpha-agonists
pharmacodynamics
Phenylephrine hydrochloride is an α-adrenoceptor agonists, has a local vasoconstrictor effect that reduces exudation, tissue swelling, itching in the anorectal region.
Indications of Relief
As a symptomatic treatment:
hemorrhoids;
anal fissures;
anal itching.
Contraindications
Increased individual sensitivity to the drug;
thromboembolic disease;
granulocytopenia;
Children up to age 12 years.
Precautions: hypertension, hyperthyroidism, diabetes, urinary retention (prostatic hypertrophy), pregnancy, lactation.
Side effects
Rarely - allergic reactions.
Interaction
Due to the content of phenylephrine reduced effect of antihypertensive drugs. When concomitant administration with antidepressants - MAO inhibitors - may develop a hypertensive crisis.
Dosage and Administration
rectal Suppositories
Rectal, after the hygiene procedures. 1 supp. in the morning and at night after each bowel movement, up to 4 times a day.
Ointment for rectal and topical
Topically, rectally, after hygiene. Remove the applicator cap, attach the applicator to a tube and squeeze a small amount of ointment to lubricate applicator.
Adults and children over 12 years - up to 4 times a day, morning, evening and after each bowel movement. Ointment gently applied through the applicator to the affected area or inside the anus and the skin in the anal region.
After each use, thoroughly rinse the applicator and place it in a protective cap.
special instructions
Do not use in children under the age of 12 years, during pregnancy and lactation without the consent of a doctor.
In case of bleeding, deterioration or no effect within 7 days you must stop using the product and consult a physician.
It should not be used in conjunction with antihypertensive drugs and MAO inhibitors.
release Form
rectal suppositories, 5 mg. The blister pack of opaque PVC foil, 6 pcs. 2 blisters in a carton box.
Rectal ointment for external use, and 2.5 mg (0.25%). The plastic tube with a polypropylene lid, 28.4 g Tube with applicator in a cardboard bundle.
Storage conditions of Relief
The temperature is not higher than 25 ° C.
Keep out of the reach of children.
Shelf life of Relief
2 years.
Do not use beyond the expiration date printed on the package.
Available without prescription.