Instruction for use: Prazosin

Trade name of the drug – Prazosin

Active substance: Prazosinum

Dosage Form: Tablets

Composition (per tablet):

Prazosin 1 tablet contains 0.5 mg or 1; Patients in the 30 pcs., in box 1 bottle.

Pharmacotherapeutic group:

Alpha-blockers

Drugs affecting the metabolism of the prostate gland and correctors urodynamics

ATX C02CA01 Prazosin

The nosological classification (ICD-10)

I10 Essential (primary) hypertension: hypertension; Arterial hypertension; Arterial hypertension crisis course; Essential Hypertension; Essential hypertension; Essential hypertension; Essential hypertension; Essential hypertension; Primary hypertension; Arterial hypertension, complications of diabetes; The sudden increase in blood pressure; Hypertensive disorders of blood circulation; hypertensive condition; hypertensive crises; arterial Hypertension; malignant Hypertension; Hypertonic disease; hypertensive crises; accelerated hypertension; malignant hypertension; The aggravation of hypertensive disease; Transient hypertension; Isolated systolic hypertension

I15 Secondary hypertension: Arterial hypertension, complications of diabetes; hypertension; The sudden increase in blood pressure; Hypertensive disorders of blood circulation; hypertensive condition; hypertensive crises; hypertension; arterial Hypertension; malignant Hypertension; hypertensive crises; accelerated hypertension; malignant hypertension; The aggravation of hypertensive disease; Transient hypertension; hypertension; Arterial hypertension; Arterial hypertension crisis course; renovascular hypertension; Hypertension symptomatic; Renal hypertension; Renovascular hypertension; renovascular hypertension; Symptomatic hypertension

I50 Heart failure: Exacerbation of chronic heart failure; Shortness of breath with acute heart failure; Acute heart failure; Acute heart failure; Heart failure on the background of intoxication; Heart failure on the background of infections; Acute Heart Failure; Chronic myocardial insufficiency; Cardiac dyspnea

Pharmacological Properties of Prazosin

Pharmachologic effect - Mode of action - vasodilator, antihypertensive.

Blocks postsynaptic alpha1-adrenergic receptors and inhibits vasoconstrictor influence of sympathetic innervation and catecholamines.

Indications for Prazosin

Arterial hypertension, congestive heart failure.

Contraindications for Prazosin

Hypersensitivity, hypotension, constrictive pericarditis, cardiac tamponade, valvular heart disease with reduced left ventricular filling pressure, pregnancy, lactation, children's age (12 years).

Prazosin Dosage and Administration

Inside, 0.5-1 mg 2-3 times a day with gradual increase in the dose - after 3 days. The maintenance dose of 3-20 mg per day in divided doses.

Side effect of Prazosin

Sudden hypotension; dizziness, headache, tachycardia, fatigue, nausea, dry mouth, increased diuresis, darkening of the eyes, allergic reactions.

Interaction

Incompatible with nifedipine. Effect increase diuretics, sympatholytic beta-blockers.

Storage conditions of Prazosin

In a dry, dark place at a temperature no higher than 25 ° C.

Keep out of the reach of children.

Shelf life

3 years

Do not use beyond the expiration date printed on the package.