Instruction for use: Plidol 100

Dosage form: tablets

Active substance: Acidum acetylsalicylicum

ATX

B01AC06 Acetylsalicylic acid

Pharmacological groups

Antiaggregants

NSAID - Salicylic acid derivatives

Nosological classification (ICD-10)

I20.0 Unstable angina: heberden disease; Angina pectoris; The attack of angina pectoris; recurrent angina; Spontaneous angina; Stable angina pectoris; Angina rest; Angina progressing; Angina mixed; Angina spontaneous; stable angina; Chronic stable angina; Angina Syndrome X

I21 Acute myocardial infarction: Myocardial infarction in the acute phase; Acute Myocardial Infarction; Myocardial infarction with pathologic Q wave and without; Myocardial infarction complicated by cardiogenic shock; Infarction left ventricular; Transmural myocardial infarction; Myocardial infarction netransmuralny (subendocardial); Netransmuralny myocardial infarction; Subendocardial myocardial infarction; The acute phase of myocardial infarction; Acute myocardial infarction;Sub-acute phase of myocardial infarction; Subacute phase of myocardial infarction; Thrombosis of the coronary arteries (the arteries); Threatened myocardial infarction; Myocardial infarction without Q wave

I25 Chronic ischemic heart disease: Coronary heart disease on the background of hypercholesterolemia; Coronary heart disease is a chronic; Coronary heart disease; Stable coronary artery disease; Percutaneous transluminal angioplasty; Myocardial ischemia, arteriosclerosis; Recurrent myocardial ischemia

I63 Cerebral infarction: ischemic Stroke; Ischemic brain disease; Ischemic stroke; Ischemic stroke and its consequences; Ischemic cerebral stroke; Ischemic cerebrovascular accident; Ischemic brain damage; Ischemic brain damage; ischemic conditions; Cerebral ischemia; Acute hypoxia brain; Acute cerebral ischemia; Acute ischemic cerebrovascular accident; Acute cerebral infarction; Acute ischemic stroke; Acute period of ischemic stroke; Focal cerebral ischemia; Ischemic stroke; recurrent stroke; The syndrome of Morgagni-Adams-Stokes; Chronic cerebral ischemia; cerebrovascular stroke; embolic stroke; Ischemic brain damage

I74 Embolism and arterial thrombosis: Thrombosis of effort (stress); Arterial thrombosis; Arteriothrombosis; Subacute and chronic arterial thrombosis; Subacute thrombosis of peripheral arteries; Postoperative thrombosis; Vascular thrombosis; Vascular embolism; Thrombosis of aortocoronary shunt; Arterial thrombosis; Thrombosis of arteries; Coronary artery thrombosis; Coronary thrombosis; Thrombosis of blood vessels; Thrombosis with ischemic stroke; Thrombosis with general surgical operations; Thrombosis in Oncology Operations; Vascular thrombosis; Thrombus formation in the postoperative period; Thrombotic complications; Thromboembolic diseases; Thromboembolic syndrome; Thromboembolic complication in the postoperative period; Thromboembolism of arteries; Partial vascular thrombosis; Embolism; Embolism of arteries

R07.2 Pain in the heart: neuroses of the heart; Myocardial ischemic pain; Pain syndrome in myocardial infarction; cardialgia; cardioneurosis; Cardiac syndrome; Pain in cardiac patients; Cardialgia on background dyshormonal myocardial dystrophy; Functional cardialgia; Psevdostenokardiya; pericardial pain

Structure and Composition

1 tablet contains 100 mg of acetylsalicylic acid; In the blister 10 pcs., In the box 2 blisters.

Pharmachologic effect

Mode of action - Antiaggregational.

It inhibits cyclooxygenase and reduces the synthesis of thromboxane A2, which has a pro-aggregation effect.

Pharmacokinetics

After taking 1 table. reliable concentrations are detected in the blood after 30 minutes, the maximum concentration is reached within 1-2 hours. It is quickly distributed to tissues and liquids, easily passes through the placental barrier, weakly penetrates into the cerebrospinal fluid. T1 / 2 - 2-3 hours. It is excreted by the kidneys, lactating mammary glands.

Indications for the drug Plidol 100

Prevention and treatment of conditions accompanied by increased platelet aggregation: acute myocardial infarction, cerebrovascular stroke; Treatment of unstable angina and transient attacks of IHD (additional therapy); Prophylaxis of aortocoronary shunt thrombosis.

Contraindications

Hypersensitivity (including to other salicylates), peptic ulcer of the stomach and duodenal ulcer (stage of exacerbation), hemorrhagic diathesis.

Side effects

Nausea, anorexia, pain in the epigastric region, erosive and ulcerative lesions and latent bleeding of the gastrointestinal tract, impaired hepatic and renal function, thrombocytopenia, allergic reactions.

Interaction

Strengthens the effect of anticoagulants and oral hypoglycemic agents, NSAID, side effects of methotrexate, reduces the effectiveness of antidotal drugs.

Dosing and Administration

Inside, the course and dose are set individually; In the usual dose - 100 mg daily.

Storage conditions of the drug Plidol 100

At a temperature of 15-25 ° C.

Keep out of the reach of children.

The shelf life of the drug Plidol 100

2 years.

Do not use beyond the expiration date printed on the package.