Instruction for use: Ocupres-E

Active substance Timolol

ATX Code S01ED01 Timolol

Pharmacotherapeutic group:

Beta-blockers

Ophthalmic tools

The nosological classification (ICD-10)

H40 Glaucoma

glaucoma intervention., Afakicheskaya glaucoma, narrow-angle glaucoma, Chronic glaucoma, Chronic open-angle glaucoma, Wide-angle glaucoma

H40.1 Primary open-angle glaucoma

open-angle glaucoma, Open-angle glaucoma, Primary glaucoma, pseudoexfoliation glaucoma, Elevated IOP

Structure and Composition

1 ml of solution contains timolol 2.5 or 5.0 mg (as maleate); in bottles of 5 ml, in the box one bottle.

pharmachologic effect

antiglaucoma.

Beta-adrenoceptor blocking. Decreases production of intraocular fluid, normal and elevated intraocular pressure without affecting the size of the pupil and visual acuity.

Clinical pharmacology

Lowering the intraocular pressure observed after 30 minutes after a single instillation. The maximum effect is achieved after 1-2 hours and lasts for the next 24 hours. The effect in cases resistant to other antiglaucoma drugs. It reduces the symptoms of hypoglycemia in diabetes.

Indications

Glaucoma (open-chronic, afakicheskaya, secondary).

Contraindications

Bronchial asthma, chronic obstructive pulmonary disease, sinus bradycardia, AV block I and II degree, expressed heart failure, cardiogenic shock, severe rhinitis expressed degenerative corneal disease.

Side effects

Burning and slight eye irritation, blurred vision, keratitis, dizziness, sleep disturbances, depression, bradycardia, hypotension, AV block, heart failure, bronchospasm, and allergic reactions.

Interaction

Simpatolitikov, calcium antagonists and systemic administration of beta-blockers potentiate hypotension, bradycardia and AV conduction oppression. Enhances the effect of catecholamines, digitalis drugs. Increases miotikami, carbonic anhydrase inhibitors.

Dosing and Administration

Kongungualno. The recommended initial dose - 1 drop of 0.25% solution of 2 times / day. If the reaction is insufficient, using 0.5% solution. With the stabilization of intraocular pressure - 1 time / day.

Precautionary measures

To use caution in patients who have contraindications to systematically receive beta-blockers, bronchial spasms, chronic heart failure and other cardiac diseases. It is necessary to control intraocular pressure. When long-term therapy should be monitored for heart rate and blood pressure. When the need for intubation anesthesia with muscle relaxant drug must be administered within 48 hours.

Storage condition

In the dark place at a temperature no higher than 25 ° C.

Keep out of the reach of children.

Shelf life

2 years.

Do not use beyond the expiration date printed on the package.