Instruction for use: Neurol 0.25

Dosage form: tablets

Active substance: Alprazolam*

ATX

N05BA12 Alprazolam

Pharmacological group:

Anxiolytics

The nosological classification (ICD-10)

F32 Depressive episode: Adynamic subdepression; Astheno-adynamic subdepressive states; Asthenodepressive disorder; Astheno-depressive disorder; Asthenodepressive state; Astheno-depressive state; Major Depressive Disorder; Vyaloapatichesky depression with retardation; Double depression; Depressive pseudodement; Depressive illness; Depressive mood disorder; Depressive disorder; Depressive mood disorder; Depressive state; Depressive disorders; Depressive syndrome; Depressive syndrome larviated; Depressive syndrome with psychoses; Depressed masks; Depression; Depression Depletion; Depression with the phenomena of inhibition within the framework of cyclothymia; Depression is smiling; Involutional depression; Involutionary melancholy; Involutional depression; Manic-depressive disorder; Masked Depression; Melancholic Attack; Neurotic depression; Neurotic depression; Shallow Depression; Organic depression; Organic depressive syndrome; Simple depression; Simple melancholic syndrome; Psychogenic depression; Reactive depression; Reactive depression with moderate psychopathological symptoms; Reactive depressive states; Reactive depression; Recurrent depression; Seasonal depressive syndrome; Severostatic depression; Senile Depression; Senile Depression; Symptomatic Depression; Somatogenic depression; Cyclotymic depression; Exogenous Depression; Endogenous depression; Endogenous Depressive Conditions; Endogenous Depression; Endogenous depressive syndrome

F40.0 Agoraphobia: Fear of open space; Fear of being in a crowd

F41.0 Panic disorder [episodic paroxysmal anxiety]: Panic state; Panic attack; Panic; Panic disorder

F41.2 Mixed anxiety and depressive disorder: Depression with anxiety-depressive components; Mixed anxiety-depressive conditions; Anxiety Depression; Anxious and depressing mood; Anxiety-depressive state; Anxious-depressive conditions; Anxiety-depressive syndrome; Anxious-Neurotic Conditions

F48 Other neurotic disorders: Neurosis; Neurological diseases; Neurotic disorders; Neurotic condition; Psychoneurosis; Anxious-Neurotic Conditions; Chronic neurotic disorders; Emotional reactive disorders

F48.0 Neurasthenia: Asthenic form of neurasthenia; Asthenoneurotic disorder; Astheno-neurotic state; Flu of young workaholics; Influenza yuppie; Neurasthenic disorders; Neurasthenic conditions; Neurasthenic syndrome

R45.1 Anxiety and agitation: Agitation; Anxiety; Explosive excitability; Internal stimulation; Excitability; Excitation; Excitation acute; Psychomotor agitation; Hyperexcitability; Motor excitement; Cessation of psychomotor agitation; Nervous excitement; Restlessness; Night trouble; Acute stage of schizophrenia with excitation; Acute mental agitation; Paroxysm of excitation; Overexcitation; Increased excitability; Increased nervous excitability; Increased emotional and cardiac excitability; Increased agitation; Mental arousal; Psychomotor agitation; Psychomotor agitation in psychoses; Psychomotor agitation of an epileptic nature; Psychomotor paroxysm; Psychomotor fit; Symptoms of excitation; Symptoms of psychomotor agitation; The state of agitation; A state of anxiety; Excitation status; A state of heightened concern; The state of psychomotor agitation; Conditions of anxiety; Excitation conditions; The state of excitement in somatic diseases; Excitation level; Feelings of anxiety; Emotional arousal

R45.4 Irritability and anger: Neurosis with increased irritability; Outbursts of anger; Anger; Resentment; Increased irritability; Increased irritability of the nervous system; Irritability; Irritability in neuroses; Irritability in psychopathic disorders; Symptoms of irritability; Dysphoria

R45.7 Condition of emotional shock and stress, unspecified: Exposure to stress factors; Exposure to extreme situations; Neuropsychic stresses; Professional stress; Psychoemotional overload and stress; Psychoemotional stress; Stressful condition; Stress; Stress loading; Stressful condition; Stressful situations; Stress of everyday life; Chronic stress; Long-term emotional stress; Psychological stress in air flights; Psychoemotional stress in stressful situations

Composition and release form

1 tablet contains alprazolam 0.25 or 1 mg; In a contour blister box 15 pcs., In a cardboard bundle 2 packs.

Pharmachologic effect

Mode of action - antidepressant, anticonvulsant, anxiolytic, myorelaxing, sleeping pills.

Interacts with benzodiazepine receptors, enhances the inhibitory effect of GABA.

Indication of the drug Neurol 0.25

Neurosis, panic and anxiety-depressive state, phobia, depression (reactive, neurotic, endogenous, accompanied by anxiety), emotional disorders.

Contraindications

Hypersensitivity, myasthenia gravis, zakratougolnaya glaucoma, pregnancy, breast-feeding.

Application in pregnancy and breastfeeding

Contraindicated in pregnancy. At the time of treatment should stop breastfeeding.

Side effects

From the nervous system and sensory organs: increased fatigue, drowsiness, violation of concentration, slowing of mental and motor reactions; Visual impairment.

On the part of the digestive tract: dry mouth, dyspeptic phenomena, impaired liver function.

Other: arterial hypotension, disorders of urination, allergic reactions, drug dependence (with prolonged use).

Interaction

Strengthens the effect of drugs that depress the central nervous system, incl. Ethanol.

Dosing and Administration

Inside, most of the dose should be taken before bedtime. The dose is set individually and adjusted during the treatment. The initial dose is 0.25-0.5 mg 3 times a day. If necessary, the dose is gradually increased to 3-4 mg, with depressive states - up to 10 mg / day. Dose reduction is carried out gradually: every 3 days no more than 0.5 mg.

Precautionary measures

Patients elderly, with a violation of the liver and kidneys require a lower dose. With caution should be used for cerebrovascular disorders of the ischemic type, patients under 18 years of age. Do not use during work drivers of vehicles and people whose profession is associated with increased concentration of attention.

Storage conditions of the drug Neurol 0,25

In a dry, the dark place at a temperature of 10-25 ° C.

Keep out of the reach of children.

Shelf life of the drug Neurol 0,25

3 years.

Do not use after the expiry date printed on the package.