Instruction for use: Medical antiseptic solution

Dosage form: solution for external use

Active substance: Ethanol

ATX

D08AX08 Ethanol

Pharmacological group:

Antiseptics and disinfectants

Composition

Active substance: ethanol (ethyl alcohol) 95% - 67.5 g;

Auxiliary substance: purified water up to 100.0 g.

Description of dosage form

Transparent colorless liquid with a characteristic smell of alcohol.

Pharmacological group

Antiseptic.

Pharmacodynamics

Antimicrobial, with local application has an antiseptic effect (denaturing proteins of microorganisms). It is active against gram-positive and gram-negative bacteria and viruses. Antiseptic activity increases with increasing ethanol concentration.

For disinfecting the skin, a 70% solution is used that penetrates deeper layers of the epidermis than a 95% solution that has a tanning effect on the skin and mucous membranes.

Pharmacokinetics

When used externally, it is absorbed from the surface of the skin and mucous membranes into the systemic circulation. Metabolised in the liver with the participation of the isoenzyme CYP2E1, the inducer of which is.

Indications

Treatment of the initial stages of diseases: furuncle, panaritium, mastitis; treatment of the hands of the surgeon (the methods of Fürbringer, Alfred), the operating field (including those with sensitivity to other antiseptics, in children and operations on areas with thin skin in adults - neck, face).

As a local irritant.

Contraindications

Hypersensitivity.

Carefully

Pregnancy, lactation, children's age.

Application in pregnancy and lactation

Special studies of the use of the drug during pregnancy and during breastfeeding were not carried out. In pregnancy and during breastfeeding apply only if the intended benefit to the mother exceeds the potential risk to the fetus and the baby.

Dosing and Administration

Outer, in the form of lotions, compresses, wipes.

To process the surgical field and pre-surgical disinfection of the hands of the surgeon, 70% solution is used, it is recommended to use a 40% solution for compresses and rubbing (to avoid burns).

70% solution must be diluted to the required concentration and used according to the indications.

Side effects

Allergic reactions, skin burns, hyperemia and soreness of the skin at the site of compression.

When used externally, it is partially absorbed through the skin and mucous membranes and may have a resorptive general toxicity (central nervous system depression).

Overdose

When the recommended dosages are increased, dose-dependent side effects may increase.

Treatment is symptomatic.

Interaction

When used concomitantly with topical preparations that contain organic compounds, it can cause denaturation of protein components.

Special instructions

In external application, ethanol is partially absorbed through the skin and mucous membranes, which must be taken into account when used in children, pregnant women and lactation.

Do not use near open flames.

Influence on ability to drive vehicles, mechanisms

A medicinal preparation used as a solution for external use does not affect the ability to drive vehicles and mechanisms. With prolonged use in large doses, it is possible to absorb into the systemic bloodstream, which can cause a decrease in psychomotor reactions, which should be taken into account when controlling vehicles and mechanisms.

Release form

Solution for external use [alcohol] 70%.

For 100 ml in bottles or in vials. Each bottle or bottle together with the instruction for use is placed in a pack of cardboard.

Storage conditions

At a temperature of 8 to 15 ° C, in a well-ukuporennoy container.

Keep out of the reach of children.

Shelf life

5 years. Do not use after the expiration date printed on the package.

Conditions of leave from pharmacies

On prescription.