Instruction for use: Lotriderm

Active substance Betamethasone + Clotrimazole

ATX code D07XC01 Betamethasone in combination with other drugs

Pharmacological group

Glucocorticosteroids in combinations

Nosological classification (ICD-10)

B35-B49 Mycoses

Fungal skin infections, Fungal lesions of skin folds, Fungal infection, Fungal skin lesions, Fungal lesions of the bronchial mucosa, Fungal lesions of the oral mucosa,Infections with fungi,Infections of the skin with fungal

B35.6 The inguinal epidermophytosis

Fungal lesions of skin folds, Dermatomycosis of the groin area and smooth skin, Mycosis of the inguinal region, Inguinal dermatophytosis, Inguinal epidermophytosis, Inguinal dermatomycosis, Mycosis of feet and large folds

B37.2 Skin and Nail Candidiasis

Fungal paronychia, Fungal Eczema, Fungal dermatosis, Fungal diseases of smooth skin, Fungal lesions of smooth skin, Fungal lesions of smooth skin of the body, Fungal nail infections, Yeast Infection of the Skin, Candidiasis of the skin, Candidiasis of skin and mucous membranes of mouth and mouth, Candidiasis of the skin of nail ridges, Candidiasis of nail rollers, Candidiasis of nails, Candidiasis with lesions of the skin and mucous membranes, Candidiasis of mucous membranes and skin, Candida paronychia, Candidomycosis of the skin, Cutaneous candidal infections, Cutaneous candidiasis, Interdigital fungal erosion, Mycotic dermatitis, Paronychia candida, Superficial form of skin candidiasis, Superficial candidiasis, Superficial candidiasis of nails, Superficial mycosis of the skin, Chronic candidiasis of the skin

Composition and form of release

1 g of cream contains clotrimazole 10 mg and betamethasone (in the form of dipropionate) 0.5 mg; In tubes of 15 and 30 g.

pharmachologic effect

Pharmacological action - anti-inflammatory, vasoconstrictive, antipruritic, antifungal broad spectrum.

Narrows the vessels, stabilizes the cell and lysosomal membranes, breaks the structure of the fungal wall (blocks the synthesis of sterols).

Pharmacodynamics

Clotrimazole is active against dermatophytes, yeast-like fungi, in particular Candida spp., As well as against trichomonads, staphylococci and streptococci.

Indications

Epidermofitiya stop, inguinal dermatomycosis, smooth skin dermatomycosis, Candidiasis caused by Candida albicans.

Contraindications

Hypersensitivity.

pregnancy and lactation

It is possible only on strict indications, if the benefits for women justify the potential risk to the fetus and baby.

Side effects

Paresthesia, maculopapular rash, burning, itching, irritation and dry skin, folliculitis, hypertrichosis, acne, hypopigmentation, perioral and allergic contact dermatitis, atrophic skin changes, maceration, striae, sweating, tingling sensation, hives, irritation and redness of the skin, puffiness , Secondary infection. In children: oppression of the hypothalamic-pituitary-adrenal system, Cushing's syndrome, increased intracranial pressure.

Dosing and Administration

Outwardly. Apply rubbing movements on the affected area and the surrounding skin 2 times a day (morning and evening); With inguinal dermatomycosis, microsporia of smooth skin and candidiasis, the duration of the course is 2 weeks, with epidermophyte stop - 4 weeks. The use of a cream for more than 4 weeks is not recommended.

Precautionary measures

Do not apply under an occlusive dressing. In the presence of bacterial infection is prescribed together with antibiotic therapy. Do not use in ophthalmology.

Storage Conditions

At a temperature of 2-30 ° C.

Keep out of the reach of children.

Shelf life

5 years.

Do not use after the expiry date printed on the package.