Instruction for use: Interferon alfa-2b + Taurine + Benzocaine

Trade name of the drug – Genferon

The Latin name of the substance Interferon alfa-2b + Taurine + Benzocaine

Interferonum alpha-2b + Taurinum + Benzocainum (genus. Interferoni alpha-2b + Taurini + Benzocaini)

Pharmacological groups:

Antiviral drugs (except HIV) in combination

Interferons in combinations

The nosological classification (ICD-10)

A56 Other chlamydial diseases, sexually transmitted infections: Chlamydial infections; Chlamydia; Tropical bubo

A59 Trichomoniasis: Trichomonas infection; Trichomoniasis; Recurrent trichomoniasis in women; Chronic trichomoniasis; Acute trichomoniasis; Chronic complicated multifocal trichomoniasis

A60 Anogenital herpetic viral infection [herpes simplex]: Herpes simplex genitalis; Banal recurrent genital herpes; Secondary genital herpes; Genital herpesvirus infection; Genital herpetic infections; Genital herpes; Herpes genitalia; Genital herpes; Herpes simplex organs; Herpetic lesions of the mucocutaneous urinary organs; Herpetic lesions of the genitals; Primary genital herpes; Primary herpes simplex; Simple herpes extragenital and genital localization; Recurrent genital herpes; Recurrent herpes of genital organs; Herpes of the lips and genitals

B37.3 Candidiasis of the vulva and vagina (N77.1 *): Vaginal candidiasis; Vaginal candidiasis; Vulval candidiasis; Vulvovaginal candidiasis; Vulvovaginal candidiasis; Vulvovaginitis candidiasis; Mycotic vulvovaginitis; Fungal vaginitis; Candidiasis of the vagina; Candidiasis of internal organs; Candidiasis of the urogenital; Candidiasis of the urogenital organs in women; Candidiasis with lesions of the skin and mucous membranes; Candidiasis of the mucous membranes; Candidiasis of mucous membranes and skin; Candidiasis of the vaginitis; Candidiasis vulvitis; Candidiasis vulvovaginitis; Colpitis of fungal etiology; Vaginal yeast infection; Moniliasis vulvovaginitis; Acute vaginal candidiasis; Acute mycosis of the vagina; Superficial candidiasis of the genital mucosa; Recurrent vaginal candidiasis; Recurrent vaginal candidiasis; Urogenital Candidiasis; Chronic vaginal candidiasis; Chronic candidiasis of mucous membranes; Chronic recurrent vaginal candidiasis

N34 Urethritis and urethral syndrome: Urethral buzhirovanie; Gonococcal urethritis; Urethrocystitis; Gonorrheic urethritis; Urethritis; Non-gonococcal urethritis; Negative urethritis; Lesion of the urethra; Acute gonococcal urethritis; Acute gonorrhea urethritis; Acute urethritis; Infection of the urethra; Bacterial nonspecific urethritis; Bacterial urethritis

N39.8 Other specified diseases of the urinary system: Inflammation of the urinary tract

N41 Inflammatory diseases of the prostate: Prostatitis; Disease of the prostate; Infection of the genitals; Chronic non-specific prostatitis

N48.1 Balanoposthitis: Non-specific balanoposthitis

N48.6 Balanitis: Balanitis dry obliterating; Fungal balanitis

N70 Salpingitis and oophoritis: Adnexitis; Inflammatory diseases of female genitalia; Inflammatory diseases of female genital organs; Infection of the genitals; Oophoritis; Acute adnexitis; Salpingitis; Salpingo-oophoritis; Chronic inflammatory diseases of the ovaries; Inflammation of the ovaries

N72 Inflammatory diseases of the cervix: Muco-purulent cervicitis; Inflammatory diseases of female genitalia; Inflammatory diseases of female genital organs; Gonococcal cervicitis; Gonorrheal cervicitis; Infection of the genitals; Non-gonorrhal cervicitis; Uncomplicated cervicitis; Nonspecific cervicovaginitis; Acute gonorrhea cervicitis; Cervicovaginitis; Cervicitis; Exocervicitis; Endocervicitis; Bacterial colpitis; Bacterial capsules

N74.4 Female pelvic inflammatory disease caused by chlamydia (A56.1 +): Chlamydial salpingitis; Chlamydial infections; Chlamydia

N75.8 Other bartholin gland diseases

N76.8 Other specified inflammatory diseases of the vagina and vulva: Genital infections; Vaginosis; Nonspecific vaginitis; Nonspecific vulvovaginitis

N86 Erosion and ectropion of the cervix: Ectopia of the cervix uteri; Ectropion of cervix uter; Vaginal erosion; Cervical erosion; Ulcers on the cervix; Cervical ectopia

Characteristics of the substance Interferon alfa-2b + Taurine + Benzocaine

Combined drug.

Pharmacology

Mode action - immunomodulating, locally anesthetic, regenerating, antimicrobial.

Interferon alfa-2 has antiviral, antimicrobial and immunomodulatory effects; Increases the activity of natural killers, T-helpers, phagocytes, as well as the intensity of differentiation of B-lymphocytes. Activation of leukocytes contained in the mucosa ensures their active participation in the elimination of primary pathological foci and provides recovery of secretory IgA production. Interferon alfa-2 also directly inhibits the replication and transcription of viruses and chlamydia.

Taurine has regenerative, reparative, membrane and hepatoprotective, antioxidant and anti-inflammatory effects.

Benzocaine is a local anesthetic; Reduces the permeability of the cell membrane for Na +. Prevents the appearance of painful impulses in the endings of the sensory nerves and their conduction along nerve fibers.

When intravaginal and rectal use, interferon alpha-2 is absorbed through the mucosa and enters the surrounding tissues, lymphatic system, providing systemic action. Due to the partial fixation on the cells of the mucous membrane has a local effect. Reduction of serum concentration of interferon alfa-2 is observed 12 hours after administration.

Application of the substance Interferon alfa-2b + Taurine + Benzocaine

Infectious and inflammatory diseases of the urogenital tract (as part of complex therapy): genital herpes, chlamydia, ureaplasmosis, mycoplasmosis, recurrent vaginal candidiasis, gardnerellez, trichomoniasis, papillomavirus infections, bacterial vaginosis, cervical erosion, cervicitis, vulvovaginitis, bartholinitis, adnexitis, prostatitis, Urethritis, balanitis, balanoposthitis.

Contraindications

Hypersensitivity, pregnancy (I-II trimester).

Restrictions

Aggravation of allergic and autoimmune diseases, pregnancy (III trimester), lactation.

Side effects of the substance Interferon alfa-2b + Taurine + Benzocaine

Allergic reactions (skin rash, itching), chills, hyperthermia, fatigue, loss of appetite, myalgia, arthralgia, headache, sweating; Leukopenia and thrombocytopenia - more often when applied at a dose exceeding 10 million units / day.

Interaction

Pharmacodynamically compatible with other drugs for the treatment of urogenital diseases (including antibiotics and other antimicrobial drugs). Vitamin E and ascorbic acid increase the effect of interferon. Non-narcotic analgesics strengthen the action of benzocaine. Benzocaine reduces the antibacterial activity of sulfonamides.

Routes of administration

Intravaginal, rectal.